Population Core (FSC)

核心人口 (FSC)

• 批准号: 8993752
• 负责人: Theresa M Bastain
• 金额: $ 26.78万
• 依托单位: UNIVERSITY OF SOUTHERN CALIFORNIA
• 依托单位国家: 美国
• 财政年份: 2015
• 资助国家: 美国
• 起止时间: 2015-09-01 至 2020-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8993752
• 关键词: Abdomen; Air Pollution; Birth; Birth Weight; Blood; California; Clip; Cohort Studies; Collaborations; Core Facility; Data; Data Collection; Development; Dietary intake; Enrollment; Ensure; Environmental Health; Environmental Risk Factor; Goals; Growth; Hair; Health; Height; Home visitation; House Call; Human Resources; Infant; Interview; Length; MRI Scans; Maintenance; Measures; Medical Records; Methodology; Monitor; Nail plate; National Institute of Environmental Health Sciences; Newborn Infant; Outcome; Physical activity; Population; Postpartum Period; Pregnancy; Pregnancy Outcome; Pregnant Women; Research; Research Infrastructure; Research Personnel; Resources; Saliva; Sampling; Spottings; Stress; Study Subject; System; Techniques; Telephone; Time; Training; Umbilical Cord Blood; Urine; Weight; Weight Gain; Woman; abdominal fat; career development; cohort; follow-up; health data; health disparity; postnatal; prenatal; programs; quality assurance; social; social stress; stressor

POPULATION CORE PROJECT SUMMARY In support of the underlying research objectives of the MADRES Center for Environmental Health Disparities, the Population Core will provide an efficient infrastructure to establish, maintain, and acquire health data from a cohort of pregnant women and their infants. The Population Core is central to the successful completion of the integrated program of research proposed in this application. Population Core activities support both Projects 1 and 2 to maximize coordination, integration and efficiency. This will be accomplished by centralizing all aspects of subject contact, health data collection and cohort maintenance for both projects. The Population Core will facilitate coordinated interactions with the Exposure Core in collecting and managing exposure data. Additionally, the Population Core will provide a centralized contact point for both projects and facilitate access to other facility core resources in other centers such as the NIEHS supported-Southern California Environmental Health Sciences Center. Specifically, the Population Core will enroll a cohort of 750 pregnant women and maintain the study cohort as a data resource; perform health data collection on the entire cohort of women during pregnancy and infants at birth; conduct follow-up data collection on the entire cohort of women and infants after birth; and facilitate the recruitment and data collection efforts for two sub-studies. The integrated coordination provided by the Population Core will reduce the need for repetitive subject contact required to accomplish the aims of both projects, establish a unified system for subject tracking, and facilitate streamlined interactions with study subjects—all of which are required for ensuring a successful approach to understanding the impacts of pre- and postnatal/postpartum environmental and social stress on infant growth and maternal weight gain and retention in an urban, environmentally- and health-disparate population.

人口核心项目概要 支持 MADRES 环境健康中心的基本研究目标 差异，核心人口将提供有效的基础设施来建立、维持和获得健康 来自一组孕妇及其婴儿的数据。核心人口是成功的关键 完成本申请中提出的综合研究计划。人口核心活动 支持项目 1 和 2，以最大限度地提高协调、整合和效率。这将实现 通过集中两个项目的受试者接触、健康数据收集和队列维护的所有方面。 人口核心将促进与曝光核心在收集和管理方面的协调互动 曝光数据。此外，人口核心将为项目和 促进访问其他中心的其他设施核心资源，例如 NIEHS 支持的南方中心 加州环境健康科学中心。具体来说，核心人口将招收 750 人 孕妇并维护研究队列作为数据资源；进行整体健康数据采集 怀孕期间的妇女和出生的婴儿的队列；对整个队列进行后续数据收集 妇女和婴儿出生后；并促进两项子研究的招募和数据收集工作。这 人口核心提供的综合协调将减少重复受试者接触的需要 需要实现两个项目的目标，建立统一的主题跟踪系统，并促进 简化与研究对象的互动——所有这些都是确保成功的方法所必需的 了解产前和产后/产后环境和社会压力对婴儿生长的影响 以及城市、环境和健康状况不同的人群中孕产妇体重的增加和保持。