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Prenatal Under Nutrition and Mortality Through Age 63 Project

Prenatal Under Nutrition and Mortality Through Age 63 Project
产前营养不足和 63 岁死亡率项目
批准号:
8816986
负责人:
L H LUMEY
金额:
$50.63万
依托单位国家:
美国
项目类别:
财政年份:
2008
资助国家:
美国
项目状态:
已结题
起止时间:
2008-04-01 至 2016-12-31

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DESCRIPTION (provided by applicant): The Dutch Famine ('Hunger Winter') of 1944-1945 provides a unique opportunity to identify early life determinants of life course health and well-being. To date, studies have concentrated on health and mortality outcomes in ~45,000 army recruits who were examined at age 18 in the early 1960s. Famine exposure in these men can be inferred from place and date of birth. Funding is now requested to link a wide variety of socio-economic outcomes (employment, wages, and disability benefits) from government sources to our studied population. The study is collaboration between epidemiologists and demographers and economists (Dr. Heckman, University of Chicago). The newly linked data will be analyzed with state-of-the-art epidemiologic and econometric approaches to reliably identify, estimate, and interpret the effects of an early life shock throughout the lifecycle. This work will integrate currently separated research traditions from the medical and social sciences and lead to a better understanding of 'fetal programming' and its implications.
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Prenatally induced DNA methylation profiles and disease risk at age 60
Prenatally induced DNA methylation profiles and disease risk at age 60
Prenatally induced DNA methylation profiles and disease risk at age 60
Exploring persistent epigenetic changes after prenatal famine exposure in humans
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