The Data Management and Statistical Core

数据管理和统计核心

• 批准号: 8883382
• 负责人: MOHAMMAD HOSSEIN RAHBAR
• 金额: $ 29.48万
• 依托单位: UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-08-01 至 2016-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8883382
• 关键词: Ankylosing spondylitis; Awareness; Bioinformatics; Biometry; Biostatistics Core; Clinical; Clinical Research; Clinical Sciences; Collaborations; Communication; Complex; Confidentiality; Data; Data Analyses; Data Collection; Data Quality; Data Storage and Retrieval; Databases; Development; Documentation; Ecology; Ensure; Epidemiologic Studies; Epidemiologist; Epidemiology; Faculty; Genetic; Genetic study; Growth; Health Sciences; Human Genetics; Human Resources; Individual; Instruction; Measures; Methodology; Monitor; Noise; Pathogenesis; Procedures; Process; Program Development; Program Research Project Grants; Public Health Schools; Publications; Quality Control; Reporting; Reproducibility; Research; Research Design; Research Personnel; Resources; Security; Solutions; Standardization; Statistical Data Interpretation; Study Subject; System; Techniques; Texas; Translational Research; Universities; clinical application; computer program; data management; database design; design; experience; innovation; programs; quality assurance; translational study

PROJECT SUMMARY (See instructions): Biostatistics, Epidemiology, and Research Design (BERD) expertise is essential to the successful conduct of clinical and translational (CT) studies. Due to extraordinary recent advancement in computational capabilities and data-driven decision processes, there has been significant growth in the number of statistical techniques and research design methodology for CT studies. The Data Management and Statistical Core (DSMC) will collaborate with the P01 investigators on the proposed projects by leveraging resources to provide study design, data management, and statistical support. DMSC specific aims include: 1. To provide research design and methodological support in the planning, conduct, and analysis of data from all proposed projects. 2. To establish and monitor systems for data collection, management, processing, quality control, data assurance, security, communication, documentation, and long term storage of data. 3. To provide statistical analysis support for researchers in this study and develop innovative study design solutions for complex study designs, encourage collaboration across studies, facilitate publications, and disseminate findings In achieving these aims, our DMSC will ensure timeliness and consistency across studies with respect to standardization of data collection forms, data entry, data cleaning, conducting data quality checks and setting up procedures for reporting and analyzing data. Our DMSC will be responsible for the overall data management, quality assurance procedures, study design and statistical analysis of the data as well as be the long-term repository of the data. Furthermore, the faculty in the DMSC will have an excellent opportunity to implement methodological improvements for conducting complex clinical and genetic studies. Database design and computer program development will be conducted in accordance with accepted best practices.

项目摘要（请参阅说明）： 生物统计学，流行病学和研究设计（BERD）专业知识对于成功进行临床和转化（CT）研究至关重要。由于计算能力和数据驱动决策过程的最新进展，统计技术和研究设计方法的数量已经显着增长。数据管理和统计核心（DSMC）将 通过利用资源提供研究设计，数据管理和统计支持，与P01调查人员在拟议项目上合作。 DMSC具体目的包括： 1。在计划，进行和分析所有提议的项目的数据中提供研究设计和方法学支持。 2。建立和监视系统，用于数据收集，管理，处理，质量控制，数据保证，安全性，通信，文档和长期存储数据。 3。为研究人员提供统计分析支持，并为复杂研究设计开发创新的研究设计解决方案，鼓励跨研究协作，促进出版物并传播发现结果 在实现这些目标时，我们的DMSC将确保有关数据收集表，数据输入，数据清洁，进行数据质量检查以及设置报告和分析数据的程序的及时性和一致性。我们的DMSC将负责数据管理的总体数据管理，质量保证程序，研究设计和数据的统计分析，并成为数据的长期存储库。此外，DMSC的教师将有一个极好的机会来实施方法学改进，以进行复杂的临床和遗传研究。数据库设计和计算机程序开发将根据公认的最佳实践进行。