Nebraska Center for Nanomedicine

内布拉斯加州纳米医学中心

基本信息

批准号：
8883588
负责人：
TATIANA K BRONICH
金额：
$ 223.15万
依托单位：
UNIVERSITY OF NEBRASKA MEDICAL CENTER
依托单位国家：
美国
项目类别：
财政年份：
2008
资助国家：
美国
起止时间：
2008-09-26 至 2016-05-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/8883588
关键词：
Address Adverse effects Area Benchmarking Biological Biological Sciences Biomedical Research Cancer Center Centers of Research Excellence Clinical Clinical Investigator Clinical Research Collaborations Communities Core Facility Development Devices Diagnosis Disease Drug Delivery Systems Early Diagnosis Environment Evolution Extramural Activities Faculty Fostering Funding Future Gene Delivery Goals Grant Growth Health Benefit Human Resources Individual Institutes International Legal patent Link Medical center Medicine Mentors Mentorship Methodology Mission Modality Nanotechnology Nebraska Pharmaceutical Preparations Pharmacologic Substance Pharmacy facility Phase Pilot Projects Productivity Publications Recombinant DNA Research Research Activity Research Infrastructure Research Personnel Research Project Grants Resources Science Scientist Societies Structure Techniques Training Translational Research Translations United States National Institutes of Health Universities Vision base bioimaging biomedical scientist career development college combat experience human disease improved innovation meetings member multidisciplinary nanomaterials nanomedicine nanoscale next generation novel novel diagnostics programs public health relevance research and development success therapeutic gene therapeutic protein tumor

项目摘要

DESCRIPTION (provided by applicant): The multidisciplinary Nebraska Center for Nanomedicine (NCN), established in 2008 with Center for Biomedical Research Excellence (COBRE) funding, is building a nationally and internationally recognized program of excellence in nanomedicine that combines broad expertise in material, pharmaceutical and biological sciences driven by innovative research. NCN has completed its original objectives and enhanced Nebraska's biomedical research capacity by creating a strategically linked infrastructure of strong collaborative research programs and by mentoring a cadre of talented junior faculty to independent success. 26 NCN members (all COBRE key personnel) have a total of 292 publications (including 86 by mentored junior faculty), 99 new patent applications along with 46 grants (16 related to nanomedicine). This NCN COBRE continuation proposal details our plan to continue building and to sustain a biomedical research center of national prominence and international recognition. The specific aims that move the NCN toward these goals over the next five years are: 1) continue to expand existing research strengths through the support of five thematically linked projects and mentorship of junior faculty into independent investigators; 2) grow research capacity through the pilot project program and the support of innovative projects by experienced researchers with a focus on expanding translational capabilities and clinical research collaborations; 3) continue targeted faculty recruitment to broaden the scope and expertise in the area of nanomedicine research; and 4) sustain the support of essential scientific core facilities, which serve as platforms to increase the capacity f NCN members to compete successfully for NIH funding. The realization of these aims will allow the NCN to emerge from Phase II funding as self-sustaining center of research excellence in nanomedicine, with an increased capacity to pursue programmatic support through individual and multi-investigator, program-wide research grants. Through the development and clinical translation of effective nanomedicines for diagnosis and therapy for human diseases, the NCN will ultimately provide significant benefits for the health of Nebraskans and society at large.

描述（由申请人提供）：纳米医学多学科的纳米医学中心（NCN）成立于2008年，由生物医学研究中心卓越基金（COBRE）资助建立，正在建立一项全国和国际认可的纳米医学卓越计划，在纳米医学方面，在纳米医学方面，在材料，药物，生物学史密斯研究中均与广泛的专业知识结合了纳米医学的卓越研究，并构建了一项综合。 NCN通过创建了策略性地联系起来的强大协作研究计划的基础架构，并指导一群才华横溢的初级教师来独立成功，从而完成了其最初的目标，并增强了内布拉斯加州的生物医学研究能力。 26名NCN成员（所有索伯尔密钥人员）共有292个出版物（包括由指导的初级教师组成的86名），99份新的专利申请以及46个赠款（16个与纳米医学有关）。这项NCN Cobre持续建议详细介绍了我们继续建立并维持国家突出和国际认可的生物医学研究中心的计划。在接下来的五年中，将NCN朝向这些目标的具体目的是：1）通过支持五个主题联系的项目和初级教师的指导，继续扩大现有的研究优势； 2）通过试点项目计划和经验丰富的研究人员对创新项目的支持增强研究能力，重点是扩大转化能力和临床研究合作； 3）继续有针对性的教师招聘，以扩大纳米医学研究领域的范围和专业知识； 4）维持基本科学核心设施的支持，该设施是提高FNCN成员成功竞争NIH资金的能力的平台。这些目标的实现将使NCN从第二阶段的资金中浮出水面，成为纳米医学卓越研究中心的自我维持的中心，并提高了通过个人和多投期计划范围内的计划范围内的研究赠款来寻求程序化支持的能力。通过对人类疾病诊断和治疗的有效纳米医学的开发和临床翻译，NCN最终将为内布拉斯加人和整个社会的健康提供重大利益。