Cancer Genetics Professional Education in a Global Community of Practice

全球实践社区中的癌症遗传学专业教育

• 批准号: 8727493
• 负责人: KATHLEEN R. BLAZER
• 金额: $ 31.25万
• 依托单位: BECKMAN RESEARCH INSTITUTE/CITY OF HOPE
• 依托单位国家: 美国
• 财政年份: 2013
• 资助国家: 美国
• 起止时间: 2013-09-01 至 2018-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8727493
• 关键词: Accountability; Action Research; Address; Behavior; Characteristics; Chicago; Cities; Clinical; Collaborations; Communities; Community Practice; Competence; Development; Distance Learning; E-learning; Educational Curriculum; Educational workshop; Environment; Evaluation; Evidence based practice; Exercise; Faculty; Fostering; Genetic; Genetic screening method; Genomics; Goals; Hereditary Malignant Neoplasm; Individual; International; Internet; Knowledge; Learning; Marketing; Mediating; Medicine; Modeling; Oncogenes; Online Systems; Outcome; Outcome Assessment; Participant; Patient Care; Patients; Prevention; Professional Education; Resources; Risk; Risk Assessment; Self Efficacy; Series; Services; Social Network; Technology; Training; Training and Education; Translating; Translations; United States; Universities; Work; base; cancer genetics; cancer genomics; cancer risk; cancer therapy; care delivery; case-based; clinical risk; community based service; comparative; design; evidence base; exome; experience; flexibility; high risk; innovation; medical specialties; novel; oncology; public health relevance; research clinical testing; screening; skills; symposium; tool

DESCRIPTION (provided by applicant): Rapidly evolving genetic/genomic technologies have revolutionized our approach to genetic cancer risk assessment (GCRA), screening, prevention and targeted cancer therapies, heralding the era of personalized medicine. Clinical testing is available for many hereditary cancer genes, and technologies are bringing whole exomes within reach. GCRA, an interdisciplinary practice, uses genetic/genomic tools and empiric risk models to identify high-risk individuals. Direct-to-consumer marketing has accelerated the demand for GCRA services from community-based clinicians, who are often inadequately prepared to select, apply and interpret genetic tests. An intensive GCRA training course was conducted to promote practitioner-level competence. The multimodal course included distance mediated didactics and face-to-face workshops, and enabled piloting of post-course professional development activities. There were significant pre-to-post increases among participants in GCRA knowledge, skills and professional self-efficacy (p<.001). Interestingly, some alumni continued to participate in professional development after fulfilling course requirements. Demand for the course [across the U.S. and internationally] exceeded capacity several-fold. These experiences and ongoing inquiries indicate a need to make GCRA training more accessible globally, and the curriculum needs to address clinical translation of new genomics. Action research identified the face-to-face component as a capacity barrier, and endorsed creation of all-distance and specialty GCRA training tracks. Comparative analysis indicated that a CME-accredited GCRA web conference series might provide effective case-based GCRA training. This project proposes the development of an innovative global Clinical Cancer Genetics Community of Practice (CCGCoP) to help address the demand for cancer genetics/genomics training and evidence-based patient care. Working from the theoretical framework of situated learning, the proposed project leverages the resources and expertise of the City of Hope, University of Chicago and U.S. Oncology Network to accomplish the following aims: Develop web-based tools, activities and collaborations to support the CCGCoP learning environment; enlist international thought leaders to create a new curriculum that includes rapidly-evolving cancer genetics/genomics content [and addresses domestic and global access issues]; develop full spectrum and all- distance subspecialty tracks as training options, and support integration of newly-trained participants into the CCGCoP through continuing professional development activities that promote GCRA skills development and evidence-based practice. The innovative design and evaluation plan encompasses longitudinal assessments of skills, practice change and patient outcomes, aligned with reformed standards of excellence in CME accountability. The ultimate goal of the CCGCoP is to increase the number of clinicians who are able to translate advances in genetics/genomics into personalized medicine globally.

描述(由申请人提供)：快速发展的遗传/基因组技术彻底改变了我们对遗传癌症风险评估(GCRA)、筛查、预防和靶向癌症治疗的方法，预示着个性化医学时代的到来。许多遗传性癌症基因的临床检测是可用的，技术正在使整个外显子变得触手可及。GCRA是一种跨学科实践，它使用遗传/基因组工具和经验风险模型来识别高危个体。直接面向消费者的营销加速了社区临床医生对GCRA服务的需求，他们往往没有足够的准备来选择、应用和解释基因测试。开展了GCRA强化培训课程，以促进从业者一级的能力。多模式课程包括远程授课和面对面讲习班，并能够试行课程后的专业发展活动。参与者在GCRA知识、技能和职业自我效能感方面有显著的提高(p&lt；.001)。有趣的是，一些校友在完成课程要求后继续参与专业发展。美国和国际上对该课程的需求超出了容量的几倍。这些经验和正在进行的调查表明，需要在全球范围内使GCRA培训更容易获得，课程需要解决新基因组学的临床翻译问题。行动研究确定面对面的内容是一种能力障碍，并赞同建立全程和专门的GCRA培训轨道。比较分析表明，经CME认可的GCRA网络会议系列可提供有效的基于案例的GCRA培训。该项目建议建立一个创新的全球临床癌症遗传学实践社区(CCGCoP)，以帮助满足癌症遗传学/基因组学培训和循证病人护理的需求。从情境学习的理论框架出发，拟议的项目利用希望城、芝加哥大学和美国肿瘤学网络的资源和专业知识来实现以下目标：开发基于网络的工具、活动和协作以支持CCGCoP的学习环境；招募国际思维领袖创建包括快速发展的癌症遗传学/基因组学内容[并解决国内和全球准入问题]的新课程；开发全光谱和全距离的子专业轨道作为培训选项，并支持整合 通过持续的专业发展活动，促进GCRA技能发展和循证实践，新培训的参与者进入CCGCoP。创新的设计和评估计划包括对技能、实践变化和患者结果的纵向评估，与改革后的继续医学教育责任卓越标准保持一致。CCGCoP的最终目标是增加能够在全球范围内将遗传学/基因组学的进步转化为个性化医学的临床医生数量。