Integrative Health Sciences Facility Core

综合健康科学设施核心(IHSFC)摘要 IHSFC支持CEET中的所有人类研究。它是允许CEET实现其战略目标的实体 执行将影响患者、社区和公众的转化性环境健康研究的愿景。 它提供高度集中的跨学科服务，包括研究设计、受试者登记、数据 管理、获取生物样本、生物统计分析、结果解释和传播 通过社区外联和参与核心(COEC)向公众公布成果。在过去的四年里， IHSFC专门专注于提供五项具体服务，包括：人体研究、设计和 性能服务、人类暴露实验室、人类暴露服务、CEET虚拟 为非基因组学和基因组学研究提供生物信息库和生物统计学支持。每项服务都提供 CEET调查人员拥有独特的工具，可以将基础研究转化为个人和人类的进步 以人口为基础的队列，以推进精确环境医学(PREM)。在双向方式中， IHSFC与COEC沟通，将基于社区的问题和关切制定为具体的 对具有人口研究专长的研究人员的假设。IHSFC的一个重要目标是 推动环境健康科学核心中心(EHS CC)在人类学科方面的合作项目。完毕 在过去四年中，涉及EHS间CC试点项目或R01对应项目的五个互动项目 已启动。IHSFC与其他中心的互动极大地扩展了EHS CCS网络的专业知识，以 解决中心间的人类研究。正如战略远景中所述，IHSFC支持综合研究 超越亲缘关系群体的人类主题以及涉及到的翻译研究团队的形成 CEET调查人员和COEC成员解决基于社区的问题。

Integrative Health Sciences Facility Core (IHSFC) Abstract The IHSFC supports all human research in the CEET. It is the entity that permits the CEET to attain its Strategic Vision to perform translational environmental health research that will impact patients, communities, and the public. It provides highly focused transdisciplinary services including study design, enrollment of subjects, data management, access to biological samples, biostatistical analyses, interpretation of results and dissemination of results to the public through the Community Outreach and Engagement Core (COEC). Over the past four years, the IHSFC has uniquely focused on delivery of five specific services that include: human studies design and performance services, human exposure laboratories, human population exposure services, CEET virtual biorepositories, and biostatistics support for both non-genomics and genomics studies. Each service provides CEET investigators with unique tools to translate fundamental research into improvements in individual human and population-based cohorts to advance PREcision Environmental Medicine (PREEM). In a bi-directional manner, the IHSFC communicates with the COEC to formulate community-based questions and concerns into specific hypotheses for investigators with expertise in population-based studies. An important goal of the IHSFC is to promote inter-Environmental Health Science Core Center (EHS CC) collaborative projects in human subjects. Over the past four years, five interactive projects involving inter-EHS CC pilot projects or R01 equivalents have been initiated. The interaction of the IHSFC with other centers greatly extends the expertise to a network of EHS CCs to address inter-center human research. As described in the Strategic Vision, the IHSFC supports integrated research themes in humans that transcend affinity groups and the formation of translational research teams that involve CEET investigators and COEC members to address community-based questions.