Mentored Clinical Scientist Research Career Development Award

指导临床科学家研究职业发展奖

基本信息

项目摘要

 DESCRIPTION (provided by applicant): The purpose of this application for a Mentored Clinical Scientist Research Career Development Award (K08) is to allow the applicant sufficient protected time to 1) develop the statistical and methodological skills necessary to perform high quality health services research, 2) develop additional skills in study design and implementation, and 3) further develop leadership and management skills to lead a productive research team. In the long term, Dr. Friedman hopes to: 1) identify areas of sub-optimal care and health care variation using administrative datasets and data from large clinical trials, 2) identify optimal cae improvement strategies within the context of comparative effectiveness research, and 3) perform clinical research to assess the validity and benefit of quality improvement initiatives. Specifically, Dr. Friedman's plan includes a focus on developing an expertise in causal inference methodology, a framework of analysis that will allow him uniquely poised to perform high-impact research in his field. Through formal biostatistical training, active participation in analysis of complex datasets, close mentorship by Dr. Cande Ananth and Dr. Jason Wright, attending lectures, journal clubs, conferences, and symposia, and performing the research analysis evaluating intrapartum care quality outlined in the application, Dr. Friedman hopes to substantially enhance his capabilities as a researcher. Dr. Friedman has identified Dr. Wright and Dr. Ananth because of their expertise in epidemiology, biostatistics, and health outcomes research as well as their long track record of successfully mentoring junior faculty. Dr. Ananth is an internationally renowned perinatal epidemiologist whose research work focuses on developing and applying innovative statistical approaches to studies in human reproduction. Dr. Jason Wright is a gynecologic oncologist, experienced clinical trialist, translational researcher, and epidemiologist. Dr. Wright and Dr. Ananth are both committed to working closely with Dr. Friedman. With increased knowledge of the complexities of biostatistics and research methodology, Dr. Friedman will gain the ability to independently perform high-quality health outcomes research. He has identified a senior advisory panel to oversee his progress and will meet quarterly with this group. The research strategy for this application is a novel population-based care quality study evaluating candidate measures for quality of intrapartum care. To summarize the study, Dr. Friedman notes that little is known about baseline adherence to obstetric practices that may be representative of care quality during labor and childbirth and how physician, provider, and patient factors influence adherence. Given that there is no agreement on how to best measure the quality of obstetric care, valid measures of intrapartum care quality are urgently needed. With his excellent mentorship team, Dr. Friedman's research plan may result in clinically relevant and useful findings that improve maternal care.
 描述(申请人提供):本申请的目的是获得指导临床科学家研究职业发展奖(K08),以使申请人有足够的受保护时间来1)发展进行高质量卫生服务研究所需的统计和方法技能,2)发展研究设计和实施方面的额外技能,以及3)进一步发展领导和管理技能,以领导一个富有成效的研究团队。从长远来看,弗里德曼博士希望:1)使用管理数据集和大型临床试验的数据来确定次优护理和医疗保健变化的领域,2)在比较有效性研究的背景下确定最佳的cae改进策略,以及3)进行临床研究以评估质量改进举措的有效性和益处。具体来说,弗里德曼博士的计划包括专注于发展因果推理方法的专业知识,这是一个分析框架,将使他能够在自己的领域进行具有高度影响力的研究。通过正式的生物统计培训、积极参与复杂数据集的分析、Cande Ananth博士和Jason Wright博士的密切指导、参加讲座、期刊俱乐部、会议和研讨会,以及进行评估产时护理质量的研究分析。弗里德曼博士希望大幅提高他作为研究人员的能力。Friedman博士已经确定了Wright博士和Ananth博士,因为他们在流行病学,生物统计学和健康结果研究方面的专业知识,以及他们成功指导初级教师的长期记录。Ananth博士是 一位国际知名的围产期流行病学家,其研究工作重点是开发和应用创新的统计方法来研究人类生殖。Jason Wright博士是一位妇科肿瘤学家、经验丰富的临床试验专家、翻译研究员和流行病学家。Wright博士和Ananth博士都致力于与Friedman博士密切合作。随着对生物统计学和研究方法的复杂性的了解的增加,弗里德曼博士将获得独立进行高质量健康结果研究的能力。他已经确定了一个高级顾问小组来监督他的进展,并将每季度与这个小组举行一次会议。本申请的研究策略是一项新的基于人群的护理质量研究,旨在评价产时护理质量的候选指标。Friedman博士指出,对产科实践的基线依从性知之甚少,这可能代表分娩和分娩期间的护理质量,以及医生,提供者和患者因素如何影响依从性。鉴于目前还没有就如何最好地衡量产科护理质量达成一致意见,迫切需要有效的分娩护理质量措施。弗里德曼博士的研究计划可能会导致临床相关和有用的发现,改善产妇护理。

项目成果

期刊论文数量(0)
专著数量(0)
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会议论文数量(0)
专利数量(0)

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Alexander M Friedman其他文献

Is it time for a large trial to evaluate aspirin for obstetric venous thromboembolism prophylaxis?
是时候进行一项大型试验来评估阿司匹林在产科静脉血栓栓塞预防中的作用了吗?
  • DOI:
    10.1016/s2352-3026(24)00374-0
  • 发表时间:
    2025-02-01
  • 期刊:
  • 影响因子:
    17.700
  • 作者:
    Alexander M Friedman
  • 通讯作者:
    Alexander M Friedman
Antenatal pyelonephritis hospitalisation trends, risk factors and associated adverse outcomes: A retrospective cohort study.
产前肾盂肾炎住院趋势、危险因素和相关不良结果:一项回顾性队列研究。
Cesarean hysterectomy for placenta accreta spectrum: Surgeon specialty-specific assessment.
侵入性胎盘的剖宫产子宫切除术:外科医生专业评估。
  • DOI:
  • 发表时间:
    2024
  • 期刊:
  • 影响因子:
    4.7
  • 作者:
    Koji Matsuo;Yongmei Huang;Shinya Matsuzaki;A. Vallejo;J. Ouzounian;Lynda D. Roman;F. Khoury‐Collado;Alexander M Friedman;J. Wright
  • 通讯作者:
    J. Wright
State-Level Indicators of Structural Racism and Severe Adverse Maternal Outcomes During Childbirth
结构性种族主义和分娩期间严重不良孕产妇结局的州级指标
  • DOI:
  • 发表时间:
    2023
  • 期刊:
  • 影响因子:
    2.3
  • 作者:
    J. Guglielminotti;G. Samari;Alexander M Friedman;R. Landau;Guohua Li
  • 通讯作者:
    Guohua Li
Peripartum cardiomyopathy delivery hospitalization and postpartum readmission trends, risk factors, and outcomes.
围产期心肌病分娩住院和产后再入院趋势、危险因素和结果。
  • DOI:
    10.1016/j.preghy.2023.11.004
  • 发表时间:
    2023
  • 期刊:
  • 影响因子:
    0
  • 作者:
    Hooman Azad;Timothy Wen;Natalie A. Bello;Whitney A. Booker;S. Purisch;M. D'alton;Alexander M Friedman
  • 通讯作者:
    Alexander M Friedman

Alexander M Friedman的其他文献

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{{ truncateString('Alexander M Friedman', 18)}}的其他基金

Modeling informatics data to track maternal risk and care quality
对信息学数据进行建模以跟踪孕产妇风险和护理质量
  • 批准号:
    10522536
  • 财政年份:
    2022
  • 资助金额:
    $ 13.07万
  • 项目类别:
Modeling informatics data to track maternal risk and care quality
对信息学数据进行建模以跟踪孕产妇风险和护理质量
  • 批准号:
    10701000
  • 财政年份:
    2022
  • 资助金额:
    $ 13.07万
  • 项目类别:
EnCoRe MOMS: Engaging Communities to Reduce Morbidity from Maternal Sepsis
EnCoRe MOMS:让社区参与降低孕产妇败血症的发病率
  • 批准号:
    10611196
  • 财政年份:
    2022
  • 资助金额:
    $ 13.07万
  • 项目类别:
EnCoRe MOMS: Engaging Communities to Reduce Morbidity from Maternal Sepsis
EnCoRe MOMS:让社区参与降低孕产妇败血症的发病率
  • 批准号:
    10927019
  • 财政年份:
    2022
  • 资助金额:
    $ 13.07万
  • 项目类别:
SCH: Prediction of Preterm Birth in Nulliparous Women
SCH:未产妇早产的预测
  • 批准号:
    9928205
  • 财政年份:
    2019
  • 资助金额:
    $ 13.07万
  • 项目类别:
SCH: Prediction of Preterm Birth in Nulliparous Women
SCH:未产妇早产的预测
  • 批准号:
    10459433
  • 财政年份:
    2019
  • 资助金额:
    $ 13.07万
  • 项目类别:
SCH: Prediction of Preterm Birth in Nulliparous Women
SCH:未产妇早产的预测
  • 批准号:
    10217258
  • 财政年份:
    2019
  • 资助金额:
    $ 13.07万
  • 项目类别:
SCH: Prediction of Preterm Birth in Nulliparous Women
SCH:未产妇早产的预测
  • 批准号:
    10018949
  • 财政年份:
    2019
  • 资助金额:
    $ 13.07万
  • 项目类别:
Mentored Clinical Scientist Research Career Development Award
指导临床科学家研究职业发展奖
  • 批准号:
    9517094
  • 财政年份:
    2015
  • 资助金额:
    $ 13.07万
  • 项目类别:

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