FASEB Science Research Conference on Skeletal Muscle Satellite and Stem Cells

FASEB 骨骼肌卫星和干细胞科学研究会议

• 批准号: 8719376
• 负责人: DAVID J GOLDHAMER
• 金额: $ 1.8万
• 依托单位: FEDERATION OF AMER SOC FOR EXPER BIOLOGY
• 依托单位国家: 美国
• 财政年份: 2014
• 资助国家: 美国
• 起止时间: 2014-06-01 至 2015-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8719376
• 关键词: Activities of Daily Living; Adult; Aging; American; Area; Basal lamina; Biology; Cell Communication; Cell Proliferation; Cell model; Cell physiology; Cells; Characteristics; Clinic; Collaborations; Colorado; Data; Developmental Process; Disease; Ensure; Environment; Evaluation; Fertilization; Fiber; Fostering; Functional disorder; Future; Goals; Growth; Heterogeneity; Homeostasis; Hypertrophy; Individual; Injury; Investigation; Knowledge; Location; Maintenance; Mammals; Mitotic; Molecular; Muscle; Muscle Fibers; Muscle function; Muscle satellite cell; Muscular Atrophy; Myopathy; Natural regeneration; Participant; Past Trends; Population; Process; Proliferating; Regulation; Research; Research Personnel; Role; Science; Signal Transduction; Skeletal Muscle; Skeletal Muscle Satellite Cells; Societies; Stem Cell Research; Stem cells; Stimulus; Students; Tissues; Translating; Underrepresented Minority; United States; Woman; Work; abstracting; age effect; age related; base; career development; cell behavior; interest; meetings; muscle degeneration; muscle regeneration; muscular structure; posters; programs; public health relevance; regenerative; response to injury; satellite cell; self-renewal; stem; stem cell biology; symposium; therapeutic development

DESCRIPTION (provided by applicant): This application seeks partial support for the upcoming Federation of American Societies of Experimental Biology (FASEB) conference entitled, "Skeletal Muscle Satellite and Stem Cells", which will be held July 20-25, 2014 in Steamboat Springs, Colorado. This will be the 8th conference focusing on satellite cell/stem cells and the 7th sponsored by FASEB. Based on trends from the past FASEB conferences held in the United States, we expect approximately 185 attendees from around the world (venue capacity for Steamboat Springs). The overall objectives of this biennial meeting include the following: 1) to provide a comprehensive analysis and integration of recent discoveries in the field with the goal of understanding the regulatory mechanisms controlling normal and abnormal functions of muscle stem cells in regeneration, muscle homeostasis, hypertrophy, aging and myopathic states; 2) to create and foster an interactive environment for the exchange of ideas and unpublished data to hasten discoveries and facilitate new and existing collaborations; 3) to provide opportunities for students and junior investigators to present their work and network with senior investigators to foster career development; 4) to facilitate career development of women and other underrepresented groups at all levels by ensuring appropriate representation in the planning, execution and participation in the conference program. No other scientific meeting has a primary focus on muscle satellite and stem cells. The need for a meeting with this focus is evidenced by the steady increase in attendance since the meeting's inception and the consistently excellent post-meeting evaluations by meeting attendees. In addition, this meeting attracts essentially all of the leading muscle stem cell researchers from around the world, further demonstrating the value of this meeting for established and future leaders in the field. The meeting will consist of eight platform sessions with a total of at least 44 speakers. A minimum of 16 speakers will be chosen from submitted abstracts based on the quality and impact of the work within the major themes of the conference, with inclusion of junior investigators being a priority in the selection process. The conference will also include three poster sessions, providing ample opportunity for students and junior investigators to present their work. Major themes will include transcriptional and posttranscriptional regulation of stem cells, satellite cel heterogeneity and potential, stem cell signaling and environmental interactions, satellite cell quiescence, activation and renewal, non-satellite stem cells, satellite cell proliferation, commitment and differentiation, muscle stem cells in growth and hypertrophy, and muscle stem cells in aging and disease. Collectively, this conference will provide a venue to present cutting edge research and promote collaborative interactions among all participants with the goal of advancing a fundamental understanding of muscle stem cell biology, and ultimately, translating this knowledge to the clinic.

描述（由申请人提供）：本申请寻求对即将于2014年7月20日至25日在科罗拉多的汽船泉举行的美国实验生物学学会联合会（FASEB）会议的部分支持，该会议题为“骨骼肌卫星和干细胞”。这将是第八届专注于卫星细胞/干细胞的会议，也是FASEB主办的第七届会议。根据过去在美国举行的FASEB会议的趋势，我们预计大约有185名来自世界各地的与会者（汽船泉的场地容量）。本次会议的总体目标包括：1）全面分析和整合该领域的最新发现，目的是了解肌肉干细胞在再生，肌肉稳态，肥大，衰老和肌病状态中控制正常和异常功能的调节机制; 2）创造和促进一个交流思想和未发表数据的互动环境，以加速发现并促进新的和现有的合作; 3）为学生和初级调查员提供机会，介绍他们的工作，并与高级调查员建立网络，以促进职业发展; 4）通过确保在会议方案的规划、执行和参与中有适当的代表性，促进妇女和其他代表性不足的群体在各级的职业发展。没有其他科学会议主要关注肌肉卫星和干细胞。自会议召开以来，与会者人数稳步增加，与会者在会后的评价一直很好，这证明有必要举行一次以此为重点的会议。此外，这次会议吸引了来自世界各地的所有领先的肌肉干细胞研究人员， 展示了本次会议对该领域现有和未来领导者的价值。会议将包括八场平台会议，总共至少有44名发言者。将根据会议主要专题范围内工作的质量和影响，从提交的摘要中选出至少16名发言者，在挑选过程中优先考虑包括初级调查员。会议还将包括三个海报会议，为学生和初级研究人员提供充分的机会来介绍他们的工作。主要主题将包括干细胞的转录和转录后调控，卫星细胞异质性和潜力，干细胞信号传导和环境相互作用，卫星细胞静止，激活和更新，非卫星干细胞，卫星细胞增殖，承诺和分化，肌肉干细胞生长和肥大，以及衰老和疾病中的肌肉干细胞。总的来说，这次会议将提供一个场地，展示前沿研究，促进所有参与者之间的协作互动，以推进对肌肉干细胞生物学的基本理解，并最终将这些知识转化为临床。