2014 Cornea, Biology & Pathobiology Gordon Research Conference Gordon Research Se

2014 角膜，生物学

• 批准号: 8641527
• 负责人: WINSTON W KAO
• 金额: $ 3万
• 依托单位: GORDON RESEARCH CONFERENCES
• 依托单位国家: 美国
• 财政年份: 2014
• 资助国家: 美国
• 起止时间: 2014-01-01 至 2014-12-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8641527
• 关键词: Address; Area; Attention; Biochemistry; Biology; Blindness; California; Cell Differentiation process; Cell Lineage; Cells; Clinic; Clinical; Collaborations; Collection; Cornea; Corneal Diseases; Corneal Endothelium; Data; Development; Discipline; Disease; Endothelial Cells; Environment; Epithelial Cells; Epithelium; Event; Eye diseases; Eyelid structure; Faculty; Floor; Fostering; Future; Gland; Goals; Grant; Health; Hepatocyte; Homeostasis; Image; Immune; Knowledge; Lacrimal gland structure; Maintenance; Mesenchymal; Molecular; Molecular Genetics; Molecular and Cellular Biology; Morphogenesis; Natural regeneration; Neural Crest Cell; Ophthalmology; Pathogenesis; Pathology; Postdoctoral Fellow; Publishing; Request for Proposals; Research; Research Personnel; Scientist; Surface Ectoderm; Time; Tissue Engineering; Tissues; Translations; Treatment Protocols; Vision; Work; Writing; career; cell type; conjunctiva; corneal epithelium; data exchange; design; experience; graduate student; improved; innovation; meetings; meibomian gland; migration; novel; ocular surface; planetary Atmosphere; posters; programs; public health relevance; restoration; structural biology; symposium; tissue reconstruction; trend

DESCRIPTION (provided by applicant): This proposal requests partial support for the third Gordon Research Conference (GRC) and the first Gordon Research Seminar (GRS) on Cornea, the Biology and Pathobiology of, in Ventura, California, February, 16-21 (GRC), and February 15 -16 (GRS) 2014. The broad and long-term goal of this Cornea-GRC & GRS is to reduce corneal blindness by fostering innovation in corneal research. Researchers and trainees will be brought together to exchange data and educate one another in a GRC format (about 165 attendees including 50-60 GRS attendees) that enables cross-disciplinary discussions and collaborations. As a result, it will improve our understanding of corneal biology and pathobiology and foster development of new treatment regimens for diseases causing corneal blindness. The theme of the third GRC: Cornea, Biology and Pathobiology will be cutting edge research examining the cell lineage and cell fate of ocular surface tissues, e.g., cornea, conjunctiva, eyelid, lacrimal glands, and Meibomian glands, during development and pathogenesis. Morpho- genesis of ocular surface tissues during development involves two major cellular events: 1. the migration and differentiation of particular mesenchymal cells of neural crest origin for the formation of ocular tissue stromal, 2. differentiation of surface ectoderm into ocular surface epithelia and glands. A better understanding of the molecular and cellular mechanisms governing the orderly migration and differentiation of cells during development will aid in the design of treatment regimens for the restoration of tissue function lost by eye disease. Invited speakers represent a variety of scientific disciplines, including molecular and cellular biology, molecular genetics, biochemistry, structural biology, imaging, tissue engineering, tissue reconstruction and clinical ophthalmology. The Conference will bring together a collection of investigators who are at the forefront of ocular surface biology, and will provide opportunities fo young investigators including graduate students, post docs and early career researchers to present their work and exchange ideas with leaders in the field. Some poster presenters will be selected for short talks in GRC. The collegial atmosphere of this Conference, with programmed discussion sessions as well as opportunities for informal gatherings in the afternoons and evenings, provides an avenue for scientists from different disciplines to brainstorm and promotes cross- disciplinary collaborations in the various research areas represented. The GRS is targeted for graduate students, post-docs, early-career scientists and young faculty providing unique forum for young investigators to discuss their work in a less intimidating environment, however, in a GRC setting. The principal topic of the GRS is The Future Directions of Corneal Research which aims to give the young investigators a notion of the new trends and new directions of cornea/ocular surface tissue research to help them design and plan their future line of research. Moreover, the meeting will have a unique Session on "How to Write a Competitive Grant" followed by an open floor discussion, which is a vital step in a young investigators career.

描述（由申请人提供）：该提案要求对第三届戈登研究会议（GRC）和第一个戈登研究研讨会（GRS），关于角膜角膜，生物学和病理学，在加利福尼亚州文图拉的生物学和病理学，2月16日至21日（GRC）（GRC），以及2月15日（GRS）（GRS）（GRS）。角膜研究的创新。研究人员和学员将被召集在一起以交换数据并以GRC格式（包括50-60 GRS参与者在内的165名参与者）相互教育，以实现跨学科的讨论和合作。结果，它将提高我们对角膜生物学和病理生物学的理解，并促进引起角膜失明的疾病的新治疗方案的发展。第三GRC的主题：角膜，生物学和病理生物学将是研究眼表组织的细胞谱系和细胞命运的尖端研究，例如，在发育和病原体期间，例如角膜，结膜，眼睑，眼睑，泪腺和叶虫腺。发育过程中眼表组织的形态起源涉及两个主要的细胞事件：1。神经rest起源的特定间充质细胞的迁移和分化是为了形成眼组织基质的形成，2。表面外胚层分化为眼角表面上皮和腺体。更好地理解有关开发过程中细胞有序迁移和分化的分子和细胞机制，将有助于设计治疗方案，以恢复因眼病而失去的组织功能。受邀的说话者代表了各种科学学科，包括分子和细胞生物学，分子遗传学，生物化学，结构生物学，成像，组织工程，组织重建和临床眼科。该会议将汇集一系列在眼表面生物学最前沿的调查人员，并将为年轻的调查人员提供机会，包括研究生，邮政文档和早期职业研究人员，以与该领域的领导者介绍他们的工作和交流想法。一些海报演示者将被选中在GRC中进行简短谈判。本次会议的合作氛围，在下午和晚上进行了计划的讨论，以及在下午和晚上进行非正式聚会的机会，为从不同学科的科学家到头脑风暴，并在各种研究领域促进了交叉学科合作。 GRS的目标是研究生，培训后，职业学院科学家和年轻教师，为年轻的研究人员提供了独特的论坛，以在不那么恐吓的环境中讨论他们的工作，但是在GRC环境中。 GRS的主要主题是角膜研究的未来方向，旨在为年轻的研究人员提供有关角膜/眼表面组织研究的新趋势和新方向的概念，以帮助他们设计和计划未来的研究线。此外，这次会议将在“如何写竞争资助”之后进行独特的会议，然后进行开放式讨论，这是年轻调查人员职业生涯中至关重要的一步。