Cell, Tissue, and Molecular Analysis
细胞、组织和分子分析
基本信息
- 批准号:8742733
- 负责人:
- 金额:$ 35.51万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2014
- 资助国家:美国
- 起止时间:2014-07-01 至 2019-04-30
- 项目状态:已结题
- 来源:
- 关键词:AdultApplications GrantsAreaBiochemistryBioinformaticsBiological AssayBiomedical EngineeringBiomedical ResearchBiophotonicsCell SeparationCellsCenters of Research ExcellenceCollaborationsCore FacilityDataDerivation procedureDevelopmentElectron MicroscopyEngineeringEnvironmentEquipmentFacultyFosteringFundingFutureGene ExpressionGenerationsGoalsGrantHistologyImageInstitutesInstitutionLaboratoriesLaboratory PersonnelLeadLearningLocationMentorsMicroscopyMolecularMolecular AnalysisMolecular BiologyMolecular Biology TechniquesNatural regenerationOrganellesOutcomeQualifyingRegenerative MedicineResearchResearch InfrastructureResearch PersonnelResearch SupportScientistServicesSignal TransductionSolutionsSouth CarolinaStem Cell ResearchStem cellsTechniquesTissue EngineeringTissuesTransfectionUnited States National Institutes of HealthUniversitiesadult stem cellbeneficiarycostexperiencein vivoinduced pluripotent stem cellmembernanoparticleprogramsprotein expressionranpirnaseresearch facilitystem cell biologytool
项目摘要
Project Summary: Cell, Tissue, and Molecular Analysis Core (CTMA core)
Cell, tissue and molecular biology techniques are the cornerstone of biomedical research. A major
hindrance for junior faculty in conducting this research is a lack of ultramodern facilities and specialized
expertise commonly found in states with major NIH funding. To advance the regenerative medicine research
potential within South Carolina, we have identified three thrust areas which will serve the needs of our SC
BioCRAFT COBRE projects: 1) molecular biology, 2) stem cell biology, and 3) histology and advanced
imaging.
Outstanding facilities and labs directed by experienced investigators with expertise in these three thrust
areas have been identified and brought together under the aegis of the Core to serve the needs of both
COBRE PIs, and other investigators statewide. To achieve the goals of the COBRE center, our core proposes
three specific aims: 1) to promote and facilitate advanced molecular biology research, 2) to enhance histology
and advanced imaging infrastructure and expertise and 3) augment adult and induced stem cell research
capabilities. The Core will be directed by experienced, NIH funded scientists with complementary expertise in
regenerative medicine, gene and protein expression and manipulation, adult and induced stem cells, and
advanced histology, electron microscopy and biophotonics.
Fully functional and generously equipped facilities in Clemson, Greenville, Spartanburg, and Charleston
SC will be joined to provide support for idea development, overcoming technical challenges and leading the
target projects towards significant outcomes. The core has an impressive potential and provides all the
necessary equipment and expertise to serve the SC investigators. Moreover, the core will foster a collaborative
mentoring environment that will serve to introduce the newest techniques available in regenerative medicine
research and greatly enhance the sustainability of our ongoing COBRE initiative.
项目概要:细胞、组织和分子分析核心(CTMA核心)
细胞、组织和分子生物学技术是生物医学研究的基石。一个主要
初级教师进行这项研究的障碍是缺乏超现代化的设施和专门的
在拥有NIH主要资金的州常见的专业知识。为了推进再生医学的研究
在南卡罗来纳州,我们已经确定了三个重点领域,这将满足我们的SC的需要
BioCRAFT COBRE项目:1)分子生物学,2)干细胞生物学,3)组织学和高级
显像
杰出的设施和实验室由经验丰富的研究人员指导,他们在这三个方面都有专业知识
已经确定了一些领域,并在核心小组的主持下汇集在一起,以满足双方的需要。
COBRE PI和全州其他调查人员。为了实现COBRE中心的目标,我们的核心建议
三个具体目标:1)促进和促进先进的分子生物学研究,2)提高组织学
先进的成像基础设施和专业知识,3)加强成人和诱导干细胞研究
能力的核心将由经验丰富的NIH资助的科学家指导,他们在以下方面具有互补的专业知识:
再生医学,基因和蛋白质表达和操作,成人和诱导干细胞,以及
高级组织学电子显微镜和生物光子学
在克莱姆森、格林维尔、斯帕坦堡和查尔斯顿提供功能齐全、设备齐全的设施
SC将加入,为创意开发提供支持,克服技术挑战,并领导
以取得重大成果为目标。核心具有令人印象深刻的潜力,并提供所有
必要的设备和专业知识,为SC调查人员服务。此外,核心将促进合作
指导环境,将有助于介绍再生医学中可用的最新技术
研究,并大大提高我们正在进行的COBRE计划的可持续性。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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Dan TEODOR Simionescu其他文献
Dan TEODOR Simionescu的其他文献
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{{ truncateString('Dan TEODOR Simionescu', 18)}}的其他基金
Elastin-derived Scaffolds for Tissue Engineered Small Diameter Vascular Grafts
用于组织工程小直径血管移植物的弹性蛋白支架
- 批准号:
8485708 - 财政年份:2011
- 资助金额:
$ 35.51万 - 项目类别:
Elastin-derived Scaffolds for Tissue Engineered Small Diameter Vascular Grafts
用于组织工程小直径血管移植物的弹性蛋白支架
- 批准号:
8274427 - 财政年份:2011
- 资助金额:
$ 35.51万 - 项目类别:
Elastin-derived Scaffolds for Tissue Engineered Small Diameter Vascular Grafts
用于组织工程小直径血管移植物的弹性蛋白支架
- 批准号:
8081205 - 财政年份:2011
- 资助金额:
$ 35.51万 - 项目类别:
Tissue Engineered Aortic Heart Valves: Scaffolds and Stem Cells
组织工程主动脉心脏瓣膜:支架和干细胞
- 批准号:
7785737 - 财政年份:2010
- 资助金额:
$ 35.51万 - 项目类别:
Tissue Engineered Aortic Heart Valves: Scaffolds and Stem Cells
组织工程主动脉心脏瓣膜:支架和干细胞
- 批准号:
8420506 - 财政年份:2010
- 资助金额:
$ 35.51万 - 项目类别:
Tissue Engineered Aortic Heart Valves: Scaffolds and Stem Cells
组织工程主动脉心脏瓣膜:支架和干细胞
- 批准号:
8215809 - 财政年份:2010
- 资助金额:
$ 35.51万 - 项目类别:
Tissue Engineered Aortic Heart Valves: Scaffolds and Stem Cells
组织工程主动脉心脏瓣膜:支架和干细胞
- 批准号:
8033770 - 财政年份:2010
- 资助金额:
$ 35.51万 - 项目类别: