Developmental Pathways of Substance Use among Sexual Minority Women

性少数女性物质使用的发展途径

• 批准号: 8981939
• 负责人: Connor J McCabe
• 金额: $ 3.93万
• 依托单位: UNIVERSITY OF WASHINGTON
• 依托单位国家: 美国
• 财政年份: 2015
• 资助国家: 美国
• 起止时间: 2015-08-16 至 2018-08-15
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8981939
• 关键词: Accounting; Address; Adolescence; Adolescent; Affect; Age; Alcohol abuse; Alcohol or Other Drugs use; Bisexual; Buffers; Childhood; Data; Data Analyses; Data Set; Development; Disease; Drug abuse; Drug usage; Early identification; Elderly; Environmental Risk Factor; Epidemiologic Studies; Equation; Factor Analysis; Goals; Growth; Heterosexuals; Individual; Intervention; Lesbian; Lesbian Gay Bisexual; Life; Longevity; Measures; Mediating; Mediation; Mediator of activation protein; Mental Health; Minority; Modeling; National Institute of Drug Abuse; Parents; Pathway interactions; Population; Populations at Risk; Prevalence; Prevention program; Preventive Intervention; Process; Prospective Studies; Psyche structure; Public Health; Relative (related person); Reporting; Research; Risk; Risk Factors; Sampling; Sex Orientation; Sexual abuse; Social support; Source; Stress; Substance Use Disorder; Targeted Research; Testing; Time; United States; Woman; Women Status; Youth; age related; coping; deter alcohol use; early childhood; emotion dysregulation; experience; girls; health disparity; inner city; innovation; intervention program; member; peer; physical abuse; physical assault; prospective; psychologic; public health relevance; resilience; response; sexual minority; stressor; theories; young adult

 DESCRIPTION (provided by applicant): Alcohol and drug abuse among sexual minority women (SMW) is an increasingly recognized public health concern in the United States. Across a multitude of nationally-representative samples, SMW populations report higher rates of substance use and disorder (SU/D) across the lifespan, and further report greater levels of adversity in both childhood and adolescence as members of a stigmatized group.1,2 Although minority stress models suggest that higher levels of adversity may explain mental health disparity among sexual minority populations,3,4 few studies have examined the impact of adversity across development among SMW in predicting SU/D in later life; none have examined psychological mediators of this proposed pathway; and none have examined moderators of this developmental pathway. The goal of the present proposal is to examine the impact of adversity on psychological risk factors of SU/D across development and address protective factors that reduce risk for later SU/D among SMW. Specifically, the proposed study will test whether adversity and subsequent increases in emotion dysregulation (ED) among SMW in childhood and adolescence account for higher levels of SU/D through young adulthood, and will examine whether social support from peers and parents within adolescence buffers this proposed risk pathway. Data will be drawn from 2,278 heterosexual and 173 sexual minority women who participated in the Pittsburgh Girls Study. The Pittsburgh Girls Study is a large, diverse sample of inner-city girls followed prospectively from age 5 to age 23, and contains a large longitudinal sample of SMW ideal for addressing the proposed study aims. Factor analysis, latent growth curve modeling (LGM), and multi-group structural equation modeling (SEM) will be used to test 1) whether ED and adversity experiences in childhood and adolescence predict increases and higher levels of SU/D through young adulthood; 2) whether ED mediates the effects of adversity and SMW status on SU/D, and whether ED moderates the impact of adolescent adversity on SU/D; and 3) whether social support moderates the effect of ED and early and adolescent adversity on later SU/D across sexual orientation groups. Addressing these questions will inform both preventative and treatment intervention efforts to reduce the prevalence of substance disorder among lesbian, gay, and bisexual populations by informing the early identification of environmental risk factors associated with sexual minority status across development; by identifying target psychological processes that have a direct impact on substance use and disorder among lesbian, gay, and bisexual individuals; and by addressing risk and resilience in the context of social support within this at-risk population.

 描述（由申请人提供）：在美国，性少数群体妇女（SMW）中的酒精和药物滥用是一个日益被认识到的公共卫生问题。在众多具有全国代表性的样本中，法定最低工资人口在整个生命周期中报告了更高的物质使用和障碍（SU/D）率，并进一步报告了作为污名化群体成员的儿童和青少年时期的更高水平的逆境。4很少有研究探讨了逆境对SMW发展的影响，以预测以后的生活中的SU/D;没有人研究过这一拟议途径的心理介质;也没有人研究过这一发展途径的调节剂。本建议的目的是研究逆境对法定最低工资者在不同发展阶段出现工作困难/残疾的心理风险因素的影响，并探讨可减低日后出现工作困难/残疾的风险的保护因素。具体而言，拟议的研究将测试是否逆境和随后增加的情绪失调（艾德）SMW在童年和青春期的解释较高水平的SU/D通过青年成年，并将研究是否从青少年的同龄人和父母的社会支持缓冲这一拟议的风险途径。数据将来自参加匹兹堡女孩研究的2，278名异性恋和173名性少数女性。匹兹堡女孩研究是一个大的，不同的样本，从5岁到23岁的城市女孩前瞻性地跟踪，并包含一个大的纵向样本SMW理想的解决拟议的研究目标。因子分析、潜在增长曲线模型（LGM）和多组结构方程模型（SEM）将用于检验1）儿童期和青少年期的艾德和逆境经历是否预测了青年期SU/D的增加和更高水平; 2）艾德是否介导了逆境和SMW状态对SU/D的影响，以及艾德是否调节了青少年逆境对SU/D的影响;社会支持是否会调节艾德和早期及青少年逆境对性取向群体后期SU/D的影响。解决这些问题将为预防和治疗干预工作提供信息，以减少女同性恋者、男同性恋者和双性恋者群体中物质障碍的流行，方法是为早期识别与整个发展过程中的性少数地位相关的环境风险因素提供信息;确定对女同性恋者、男同性恋者和双性恋者的物质使用和障碍有直接影响的目标心理过程;并在社会支持的背景下，在这一高危人群中解决风险和复原力问题。