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Emotion Dysregulation and Risky Behavior Among People Who Inject Drugs

注射毒品者的情绪失调和危险行为

基本信息

批准号：
8845401
负责人：
MARY ELLEN MACKESY-AMITI
金额：
$ 23.87万
依托单位：
UNIVERSITY OF ILLINOIS AT CHICAGO
依托单位国家：
美国
项目类别：
财政年份：
2015
资助国家：
美国
起止时间：
2015-07-01 至 2017-06-30
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/8845401
关键词：
Acquired Immunodeficiency Syndrome Address Affect Alcohol consumption Alcohol or Other Drugs use Area Behavior Blood Borderline Personality Disorder Car Phone Characteristics Chicago Communities Complex Cross-Sectional Studies Data Development Devices Disease Drug user Ecological momentary assessment Electronics Emotional Emotions Enrollment Epidemic Equipment Event Goals HIV Handheld Computers Hepatitis C Hepatitis C virus Hospitalization Impulsivity Injection of therapeutic agent Intervention Laboratory Study Life Major Depressive Disorder Measures Mediating Mental Depression Mental Health Mental disorders Methodology Methods Moods Morbidity - disease rate Needle Sharing Participant Persons Pharmaceutical Preparations Preventive Intervention Reporting Research Risk Risk Behaviors Risk Factors Role Sample Size Sampling Shares syringes Social Network Symptoms Testing Time Variant design emotion dysregulation emotion regulation intervention program meetings metropolitan public health relevance sex risk transmission process

项目摘要

DESCRIPTION: Sharing of syringes and other injection equipment among people who inject drugs (PWID) is a significant risk factor for transmission and acquisition of blood-borne diseases including HIV and hepatitis C. A recent study of young PWID in the Chicago metropolitan area found that over 40% used a shared syringe, and over 75% shared other injection equipment in the past six months. This study also found that substance- induced major depression (SIMD) and borderline personality disorder (BPD) were significantly associated with receptive syringe sharing. Emotion dysregulation is a hallmark symptom of BPD, and is implicated in major depressive disorders. These findings point to the possible role of negative affect and emotion regulation difficulties in perpetuating injection risk behavior. Prevention intervention programs for PWID may be able to help address these problems, however further research is needed to elucidate the mechanisms that drive the linkages between negative affect, emotion dysregulation and HIV/HCV risk behavior among young PWID. In order to more fully understand the relationship between emotion dysregulation and HIV/HCV risk behavior, we need to collect data in real-time, in the context of everyday activities. Ecological momentary assessment (EMA) is a method for collecting such data, commonly using a portable electronic device such as a handheld computer or mobile phone. This methodology greatly reduces biases associated with retrospective recall, and can capture the interplay of mood and behavior over time. We will use a stratified random time-sampling design to obtain a representative sample of PWID's emotional state, substance use, and injection behavior over a 2-week period. Baseline assessments will be conducted to evaluate mental health and emotion dysregulation. This study will test the acceptability and feasibility of ecological momentary assessment (EMA) to study mood and behavior in young people who inject drugs (PWID), and will gather preliminary data on emotion regulation, mood, and injection behavior among young PWID in the context of everyday activities. The results of this study will inform the development of a larger study to examine the associations among negative affect, emotion dysregulation, and injection risk behavior in PWID. This research will have implications for intervention practices for PWID with emotion regulation difficulties, to reduce risky injection behavior and to promote entry into treatment for substance use and mental health.