Emotion Dysregulation and Risky Behavior Among People Who Inject Drugs

注射毒品者的情绪失调和危险行为

• 批准号: 9271353
• 负责人: MARY ELLEN MACKESY-AMITI
• 金额: $ 0.85万
• 依托单位: UNIVERSITY OF ILLINOIS AT CHICAGO
• 依托单位国家: 美国
• 财政年份: 2015
• 资助国家: 美国
• 起止时间: 2015-07-01 至 2017-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9271353
• 关键词: Acquired Immunodeficiency Syndrome; Address; Affect; Alcohol consumption; Alcohol or Other Drugs use; Area; Behavior; Blood; Borderline Personality Disorder; Car Phone; Characteristics; Chicago; Communities; Complex; Cross-Sectional Studies; Data; Development; Disease; Drug user; Ecological momentary assessment; Electronics; Emotional; Emotions; Enrollment; Epidemic; Equipment; Event; Goals; HIV/HCV; Handheld Computers; Health; Hospitalization; Impulsivity; Injecting drug user; Injection of therapeutic agent; Intervention; Laboratory Study; Life; Major Depressive Disorder; Measures; Mediating; Mental Depression; Mental Health; Mental disorders; Methodology; Methods; Moods; Morbidity - disease rate; Needle Sharing; Participant; Persons; Preventive Intervention; Reporting; Research; Risk; Risk Behaviors; Risk Factors; Role; Sample Size; Sampling; Shares syringes; Social Network; Symptoms; Testing; Time; Variant; design; emotion dysregulation; emotion regulation; intervention program; meetings; metropolitan; negative affect; sex risk; transmission process

 DESCRIPTION: Sharing of syringes and other injection equipment among people who inject drugs (PWID) is a significant risk factor for transmission and acquisition of blood-borne diseases including HIV and hepatitis C. A recent study of young PWID in the Chicago metropolitan area found that over 40% used a shared syringe, and over 75% shared other injection equipment in the past six months. This study also found that substance- induced major depression (SIMD) and borderline personality disorder (BPD) were significantly associated with receptive syringe sharing. Emotion dysregulation is a hallmark symptom of BPD, and is implicated in major depressive disorders. These findings point to the possible role of negative affect and emotion regulation difficulties in perpetuating injection risk behavior. Prevention intervention programs for PWID may be able to help address these problems, however further research is needed to elucidate the mechanisms that drive the linkages between negative affect, emotion dysregulation and HIV/HCV risk behavior among young PWID. In order to more fully understand the relationship between emotion dysregulation and HIV/HCV risk behavior, we need to collect data in real-time, in the context of everyday activities. Ecological momentary assessment (EMA) is a method for collecting such data, commonly using a portable electronic device such as a handheld computer or mobile phone. This methodology greatly reduces biases associated with retrospective recall, and can capture the interplay of mood and behavior over time. We will use a stratified random time-sampling design to obtain a representative sample of PWID's emotional state, substance use, and injection behavior over a 2-week period. Baseline assessments will be conducted to evaluate mental health and emotion dysregulation. This study will test the acceptability and feasibility of ecological momentary assessment (EMA) to study mood and behavior in young people who inject drugs (PWID), and will gather preliminary data on emotion regulation, mood, and injection behavior among young PWID in the context of everyday activities. The results of this study will inform the development of a larger study to examine the associations among negative affect, emotion dysregulation, and injection risk behavior in PWID. This research will have implications for intervention practices for PWID with emotion regulation difficulties, to reduce risky injection behavior and to promote entry into treatment for substance use and mental health.

 产品说明：注射吸毒者之间共用注射器和其他注射器具是传播和获得包括艾滋病毒和丙型肝炎在内的血液传播疾病的一个重要风险因素。最近一项对芝加哥大都市地区年轻的PWID的研究发现，在过去的六个月里，超过40%的人使用共用注射器，超过75%的人共用其他注射设备。本研究还发现，物质诱发的重性抑郁症（SIMD）和边缘型人格障碍（BPD）与接受性共用注射器显著相关。情绪失调是BPD的标志性症状，并与重度抑郁症有关。这些发现指出了负面影响和情绪调节困难在延续注射风险行为中可能发挥的作用。针对PWID的预防干预计划可能有助于解决这些问题，但需要进一步的研究来阐明年轻PWID中负面影响，情绪失调和HIV/HCV风险行为之间联系的机制。为了更全面地了解情绪失调与HIV/HCV风险行为之间的关系，我们需要在日常活动的背景下实时收集数据。生态瞬时评估（EMA）是一种收集此类数据的方法，通常使用便携式电子设备，如手持计算机或移动的电话。这种方法大大减少了与回顾性回忆相关的偏差，并且可以捕捉情绪和行为随着时间的推移的相互作用。我们将使用分层随机时间抽样设计，以获得PWID的情绪状态，物质使用和注射行为在2周内的代表性样本。将进行基线评估，以评估心理健康和情绪失调。本研究将测试生态瞬时评估（EMA）的可接受性和可行性，以研究情绪和行为的年轻人谁注射毒品（PWID），并将收集初步数据的情绪调节，情绪和注射行为的年轻人在日常活动的背景下。本研究的结果将为更大规模的研究提供信息，以研究PWID中的负面影响，情绪失调和注射风险行为之间的关联。这项研究将对PWID情绪调节困难的干预实践产生影响，以减少危险的注射行为，并促进进入物质使用和心理健康的治疗。

项目成果

Negative affect, affect-related impulsivity, and receptive syringe sharing among people who inject drugs.

• DOI: 10.1037/adb0000590
• 发表时间: 2020-11
• 期刊: Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors
• 作者: Mackesy-Amiti ME;Boodram B;Donenberg G
• 通讯作者: Donenberg G

Feasibility of ecological momentary assessment to study mood and risk behavior among young people who inject drugs.

• DOI: 10.1016/j.drugalcdep.2018.03.016
• 发表时间: 2018-06-01
• 期刊: Drug and alcohol dependence
• 影响因子: 4.2
• 作者: Mackesy-Amiti ME;Boodram B
• 通讯作者: Boodram B