印第安纳大学痴呆症筛查试验：IU CHOICE 研究-猫眼课题宝

印第安纳大学痴呆症筛查试验：IU CHOICE 研究

批准号：

8705975

负责人：

MALAZ BOUSTANI

金额：

$53.47万

依托单位：

INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS

依托单位国家：

美国

项目类别：

财政年份：

2012

资助国家：

美国

项目状态：

已结题

起止时间：

2012-08-15 至 2017-06-30

来源：

https://reporter.nih.gov/project-details/8705975

关键词：

Advance Care Planning Advisory Committees Advocate Alzheimer&apos s Disease American Anxiety Anxiety Disorders Behavioral Caregivers Caring Clinic Clinical Trials Cognitive Control Groups Counseling Coupled Data Dementia Diagnosis Disease Early Diagnosis Early identification Early treatment Elderly Equipment and supply inventories Future Healthcare Healthcare Systems Indiana Influentials Institute of Medicine (U.S.)Institutes Intervention Lead Literature Measures Medicare Memory impairment Mental Depression Modeling Moods Patient Care Patients Performance Phase Population Heterogeneity Prevention Preventive Primary Health Care Procedures Process Protocols documentation Questionnaires Randomized Randomized Controlled Trials Relative (related person)Reporting Research Research Activity Research Design Research Personnel Resources Services Source Symptoms Syndrome Testing United States United States Centers for Medicare and Medicaid Services Universities Visit aged beneficiary biopsychosocial chronic care model collaborative care control trial cost depressive symptoms evidence base functional disability health care service utilization improved interest neuropsychiatry pressure primary care setting primary outcome programs psychologic public health relevance screening systematic review therapeutic target tool treatment as usual

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DESCRIPTION (provided by applicant): The United States Preventive Services Task Force (USPSTF) found no clinical trial that evaluated the efficacy of dementia screening in primary care. Pressures to institute screening of unproved benefit could divert much needed resources from health care systems and have an overall negative impact on care for patients with dementia and other illnesses, ultimately reducing current opportunities for dementia recognition. Using the framework of the chronic care model and evidence-based, comprehensive biopsychosocial dementia care protocols, our investigators developed and conducted a randomized controlled trial of a Collaborative Dementia Care Management program and found that such a program improves the behavioral and psychological symptoms related to dementia care and reduced the burden of dementia relative to usual care. Study Design: A two-phase randomized controlled dementia screening trial among 4,000 Americans aged 75 and older attending urban primary care clinics in Indianapolis, Indiana. Intervention: A dementia screening procedure followed by a Collaborative Dementia Care program. Controls: The study will have two control groups: "No Screening" and "Screening Only" groups. Primary Outcome of Potential Benefits: Behavioral and psychological symptoms related to dementia as measured by the Neuropsychiatric Inventory (NPI) at 18 months of randomization. Primary Outcome for Potential Harms: Mood and anxiety symptoms as measured by the PHQ-9 and GAD-7 at 18 months of randomization. Impact: The results of this study will help guide the United States Preventive Services Task Force in the decision to recommend for or against routine screening for dementia in primary care. In addition, the data generated by our proposed study could be used to model the impact of future pharmacological therapeutics targeting dementia but requiring early recognition of the syndrome as can occur if screening is done routinely among elders.

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