(2/2) Howard University/Johns Hopkins Partnership in HPV-Related Cancer Research

(2/2) 霍华德大学/约翰·霍普金斯大学在 HPV 相关癌症研究方面的合作伙伴关系

• 批准号: 8930942
• 负责人: TZYY-CHOOU WU
• 金额: $ 19.02万
• 依托单位: JOHNS HOPKINS UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2014
• 资助国家: 美国
• 起止时间: 2014-09-20 至 2018-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8930942
• 关键词: Accounting; Address; African American; Applications Grants; Area; Attitude; Awareness; Baltimore; Cancer Center; Cancer Research Project; Caucasians; Collaborations; Communities; Comprehensive Cancer Center; Data; Dental; Dental Facilities; Dental Faculty; Dental Students; Dentistry; Dentists; Development; Diagnosis; District of Columbia; Education; Ensure; Epidemiologic Studies; Etiology; Face; Faculty; Funding; Funding Opportunities; Goals; Grant; Head and Neck Cancer; Health; Health education; Hispanics; Historically Black Colleges and Universities; Home environment; Human Papilloma Virus Vaccine; Human Papillomavirus; Human papillomavirus 16; Incidence; Institution; Knowledge; Lead; Learning; Malignant Neoplasms; Malignant Vaginal Neoplasm; Malignant neoplasm of anus; Malignant neoplasm of cervix uteri; Maryland; Medical; Medical Research; Medical Students; Medicine; Mentors; Mentorship; Minority; Minority-Serving Institution; Motivation; NCI-Designated Cancer Center; National Cancer Institute; Oropharyngeal; Participant; Patients; Pilot Projects; Population; Preparation; Prevention; Process; Publications; Research; Research Personnel; Research Project Grants; Research Training; Resources; Scientist; Services; Students; System; Training; Training and Education; Translational Research; Underrepresented Minority; Underserved Population; United States; United States National Institutes of Health; Universities; Washington; Woman; anticancer research; base; cancer diagnosis; cancer education; cancer health disparity; career; career development; cohort; college; health disparity; improved; malignant mouth neoplasm; malignant oropharynx neoplasm; metropolitan; mouse model; multidisciplinary; programs; public health relevance; reproductive; skills; socioeconomic disparity; undergraduate student; university student; vaccine development

 DESCRIPTION (provided by applicant): This proposal aims to improve the translational and community-based HPV-associated cancer research, education, and training at Howard University through collaborative projects and an effective long-term partnership with Johns Hopkins Medical Institutions Sidney Kimmel Comprehensive Cancer Center. Human papillomavirus (HPV) accounts for 5.2% of cancer cases worldwide. Several strains of HPV cause a variety of devastating reproductive and oropharyngeal cancers. In the United States, about 26,700 cases of HPV-associated cancers are diagnosed annually. African American women suffer from a significantly higher incidence rate of HPV-associated cervical, vaginal, and anal cancers compared to their Caucasian counterparts. Additionally, HPV-16 has been identified in approximately 20-30% of head and neck cancers and roughly 56% of oropharynx and oral cavity cancers. Howard University Medical Institutions have a historically Black student body, and its medical and dental facilities participate in direct service to minority populations. However, Howard University faces significant challenges in cancer research and health disparities efforts. Johns Hopkins is committed to providing mentorship and educational resources in cancer research to improve Howard's capacities. Howard is a leading minority-serving institution, while Johns Hopkins is a well-established NCI-designated Cancer Center. An educational effort that brings together Howard doctors and dentists who focus on minorities and Johns Hopkins researchers who study HPV-related cancers will help to address socioeconomic disparities and barriers to cancer health, health education, and health-related professions. Through a set of collaborative pilot projects that include HPV vaccine development in mice models, epidemiology research in a Washington D.C. community cohort, and an extensive mentoring network between the two universities, this collaboration will significantly enhance career development, education, and competitiveness in seeking funding opportunities for Howard students and educators. Specific aims will be: 1) to support collaborative cancer research projects between the Howard University Medical Institutions and the Sidney Kimmel Cancer Center at Johns Hopkins; 2) to provide collaborative training and mentoring programs for promoting Howard medical and dental students and faculty in cancer research, 3) to establish education programs that advance the knowledge of cancer research as it applies to etiology, prevention, diagnosis, and treatment of HPV-associated cancer in the context of minority-serving institutions.