Killing infected cells as a mechanism to eradicate tuberculosis

杀死受感染的细胞作为根除结核病的机制

• 批准号: nhmrc : 1147010
• 负责人: Dr Nicholas West
• 金额: $ 72.4万
• 依托单位: The Walter and Eliza Hall Institute of Medical Research
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2018
• 资助国家: 澳大利亚
• 起止时间: 2018-01-01 至 2021-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/killing-infected-cells-eradicate-tuberculosis/1320778
• 关键词: Killing; infected; cells; mechanism; eradicate

Mycobacterium tuberculosis (Mtb), the causative agent of TB, is rapidly becoming resistant to all antibiotics and this disease kills more than one million people each year. This underscores the urgent need to develop new treatments for this disease. We are developing a therapy that kills Mtb infected cells and may help to eradicate infection. This highly novel approach to the treatment of TB would have profound implications for the 2 billion people infected with this pathogen.

结核分枝杆菌（Mycobacterium tuberculosis，Mtb）是结核病的病原体，其对所有抗生素的耐药性正在迅速增强，每年有超过100万人死于这种疾病。这表明迫切需要开发新的治疗方法。我们正在开发一种杀死结核杆菌感染细胞的疗法，可能有助于根除感染。这种治疗结核病的非常新颖的方法将对感染这种病原体的20亿人产生深远的影响。