Behavioral Function Core

行为功能核心

• 批准号: 8894377
• 负责人: PATRICIO T HUERTA
• 金额: $ 35.05万
• 依托单位: FEINSTEIN INSTITUTE FOR MEDICAL RESEARCH
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/8894377
• 关键词: Behavior assessment; Behavioral; Brain; Cognition; Cognitive; Core Facility; Data Analyses; Data Storage and Retrieval; Ensure; Equipment; Exhibits; Human Resources; Immune; Impairment; Individual; Long-Term Potentiation; Memory; Modeling; Mouse Strains; Mus; Nervous System Physiology; Procedures; Process; Sepsis; Slice; Stimulus; Survivors; Technical Expertise; Testing; Training; behavior test; behavioral study; cognitive function; cognitive task

Behavioral Function - Core C Individuals surviving sepsis exhibit impaired cognitive function. We are modeling this process in mice. The Behavioral Function Core will subject mice to a battery of assessments of neurologic function including behavioral and cognitive tasks. In addition, the Core will assess long term potentiation in brain slices of mice. The use of a Core facility for these studies will ensure the involvement of trained personnel, standardized procedures, and standardized data analyses and so will facilitate comparability across all, projects. All Core personnel will have undergone the same training so all mice will be exposed to the same test, as well non test, stimuli.

行为功能-核心C 脓毒症幸存者表现出认知功能受损。我们正在小鼠中模拟这一过程。的 行为功能核心将对小鼠进行一系列神经功能评估，包括 行为和认知任务。此外，核心将评估脑切片中的长时程增强， 小鼠使用核心设施进行这些研究将确保训练有素的人员参与， 标准化的程序和标准化的数据分析，因此将促进所有方面的可比性， 项目所有核心人员将接受相同的培训，因此所有小鼠将暴露于相同的环境中。 测试，以及非测试，刺激。