Development and Evaluation of a Preventive Intervention for Children with FASD

胎儿酒精谱系谱系障碍 (FASD) 儿童预防性干预措施的制定和评估

基本信息

批准号：
8883086
负责人：
CHRISTIE Lynn McGee Petrenko
金额：
$ 12.2万
依托单位：
UNIVERSITY OF ROCHESTER
依托单位国家：
美国
项目类别：
财政年份：
2011
资助国家：
美国
起止时间：
2011-07-20 至 2016-08-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/8883086
关键词：
Adolescence Adult Advocacy Affect Alcohol or Other Drugs use Area Attention Behavior Caregivers Child Child Rearing Communities Competence Development Development Plans Educational Curriculum Educational Intervention Ensure Etiology Evaluation Faculty Family Feasibility Studies Feedback Fetal Alcohol Exposure Fetal Alcohol Spectrum Disorder Fetal Alcohol Syndrome Focus Groups Fostering Foundations Goals Home environment Individual Intervention Intervention Studies K-Series Research Career Programs Knowledge Laws Mental Health Mentors Methodology Methods Outcome Participant Pathway interactions Population Prevention Preventive Intervention Probability Psychopathology Public Health Quality of life Randomized Controlled Trials Recording of previous events Research Research Personnel Resources Risk Risk Factors Schools Science Severities Sex Behavior Social Welfare Societies Solutions Stress Substance abuse problem Testing Training Training Activity Universities Work adverse outcome alcohol exposure burden of illness career development clinically significant cost cost effective design efficacy testing efficacy trial emotional behavior executive function experience follow-up implementation trial improved information processing interest life time cost multidisciplinary post intervention prevent programs service utilization skills social skills theories therapy design

项目摘要

DESCRIPTION (provided by applicant): Dr. Christie McGee Petrenko will be joining the faculty of the Mt. Hope Family Center at the University of Rochester in July 2011. Her long-term goal is to establish a productive program of research focusing on the prevention of adverse outcomes (e.g., mental health problems, trouble with the law, substance use) in children with prenatal alcohol exposure. As outlined in her Career Development Plan, a multidisciplinary team of experts will provide her with advanced training and mentoring in several areas, including: prevention science, developmental psychopathology, intervention design and implementation, randomized controlled trials, and longitudinal methodology. Advanced training in these areas will serve as an excellent foundation for Dr. Petrenko to continue her program of research and foster her development as an independent researcher. The proposed research will incorporate multiple methods to rigorously develop and evaluate a preventive intervention for children with prenatal alcohol exposure (grades K-2). The preliminary framework of the proposed intervention includes concurrent child and caregiver skills groups and individualized family advocacy. The intervention will target multiple short- and long-term outcomes, including mental health, school adjustment, social competence, delinquency, parenting, and home environment. Pre-intervention research will inform the content and framework of the preventive intervention. Specifically, focus groups will be conducted with key community stakeholders (caregivers and helping professionals) to evaluate perceived needs and the acceptability of the proposed intervention. Once a tailored intervention is developed, an implementation trial will be conducted to fine-tune the curriculum and ensure the preventive intervention is feasible and engaging for families. The intervention will then be piloted and evaluated through a randomized controlled trial. The proposed preventive intervention aims to improve competence and reduce risk factors for children with prenatal alcohol exposure and increase the likelihood that they will continue on an adaptive developmental trajectory. This intervention has the potential to improve the quality of life for children with FASD and their families and reduce the significant costs to society that accompany prenatal alcohol exposure. This research will also be applied more broadly to test current theories of developmental psychopathology and prevention science, which will improve our understanding of the etiology and malleability of maladaptive behaviors.

描述（由申请人提供）：Christie McGee Petrenko博士将于2011年7月加入罗切斯特大学希望家庭中心的教职员工。她的长期目标是建立一项富有成效的研究计划，以预防不良后果（例如，在法律上使用，有麻烦，药物的使用，药物使用）的儿童prenatatal酒精含量持续的研究（例如，精神健康问题）正如她的职业发展计划中概述的那样，一个多学科的专家团队将在多个领域为她提供高级培训和指导，包括：预防科学，发展心理病理学，干预设计和实施，随机对照试验和纵向方法论。这些领域的高级培训将为Petrenko博士继续她的研究计划并促进她作为独立研究人员的发展。拟议的研究将结合多种方法，以严格开发和评估针对产前酒精暴露儿童的预防性干预（K-2年级）。拟议的干预措施的初步框架包括并发的儿童和照料者技能群体以及个性化的家庭倡导。干预措施将针对多个短期和长期成果，包括心理健康，学校调整，社会能力，犯罪，育儿和家庭环境。干预前研究将为预防干预的内容和框架提供信息。具体来说，将与关键的社区利益相关者（护理人员和帮助专业人员）一起评估所感知的需求和拟议干预的可接受性。一旦制定了量身定制的干预措施，将进行实施试验，以微调课程，并确保预防性干预是可行的和对家庭的参与度。然后，将通过一项随机对照试验对干预进行试验和评估。拟议的预防性干预旨在提高能力并减少产前酒精暴露儿童的危险因素，并增加他们继续适应性发展轨迹的可能性。这种干预措施有可能改善FASD儿童及其家人的生活质量，并减少伴随产前酒精暴露的社会的巨大成本。这项研究还将更广泛地用于检验当前的发育心理病理学和预防科学理论，这将提高我们对适应不良行为的病因和锻造性的理解。