A neuroprosthesis for seated posture and balance
用于坐姿和平衡的神经假体
基本信息
- 批准号:8486090
- 负责人:
- 金额:--
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2013
- 资助国家:美国
- 起止时间:2013-08-01 至 2017-07-31
- 项目状态:已结题
- 来源:
- 关键词:AbdomenAccelerationActivities of Daily LivingClinicalClinical TrialsCommunitiesConsciousDataDisabled PersonsEnvironmentEquilibriumFall preventionFlexorFutureGenerationsHealthHealthcare SystemsHip region structureHome environmentImplantInterventionLateralLeisure ActivitiesLifeLife StyleManual wheelchairMeasuresMechanicsMuscleParalysedPatternPerceptionPerformancePersonal SatisfactionPhasePopulationPosturePreparationProceduresRecruitment ActivitySafetySelf StimulationSignal TransductionSpecific qualifier valueSpeedSpinal cord injuryStimulusStrokeSurfaceSystemTelemetryVeteransWheelchair propulsionWheelchairsWireless TechnologyWorkbasefallsfear of fallingimplantable deviceimprovedneuroprosthesisnew technologyprogramspublic health relevancesensorskeletalsocialtelemetering
项目摘要
DESCRIPTION (provided by applicant):
Spinal cord injury (SCI) can result in paralysis of the core trunk and hip musculature which compromises the ability to stabilize the torso while reaching, resist disturbances to sitting balance, and efficiently propel a manual wheelchair. Constant stimulation of the trunk and hip extensor muscles can positively alter seated posture, extend bimanual reach, restore erect sitting, and improve wheelchair propulsion mechanics at slow speeds and on level surfaces. However, continuously activating the trunk and hip extensors is unresponsive to the dynamically changing demands of many activities of daily living and does not contribute to attaining forward leaning postures or resisting rearward directed disturbances. First-generation systems also require users to intentionally select a discrete pattern of stimulation for each desired function from a fixed menu of pre-programmed options. The purpose of this study is to expand the functional impact of neuroprostheses for seated posture and balance by a) incorporating the abdominal and hip flexor muscles to enhance trunk stiffness through co-contraction with the extensors, b) synchronizing stimulation with the stroke cycle to improve wheelchair propulsion efficiency, c) providing automatic righting actions to maintain upright posture, prevent falls and
extend forward reach, and d) integrating these approaches into an advanced sensor-driven trunk control system with currently available implantable devices in preparation for transitioning
to new technologies suitable for clinical dissemination. The implanted EMG telemetry and expanded channel count of our second-generation implanted stimulator-telemeter (IST) will be utilized to implement advanced neuroprostheses for seated function. Two channels of EMG data will detect transitions between contact and return phases of propulsion and switch between appropriate stimulus patterns without conscious effort by the user. Performance of continuous co-activation of the hip/trunk flexor and extensor muscles will be compared to phasic activation of the muscles in terms of propulsion mechanics, efficiency, and subjective perception of effort on level and inclined surfaces and at various speeds. Control systems based on an inexpensive commercially available wireless 3D accelerometer will be implemented to detect impending forward or lateral falls and appropriately modulate stimulation to restore upright posture and sitting balance. Efficacy will be evaluated in terms of forward reach, rejection of disturbances, independence and safety of transfers, and both patterns of usage and fear of falling in the home and community environments. Complementary information from upper body EMG and trunk accelerations will be combined into a single control system to automatically regulate stimulation for self-righting and propulsion over various surfaces and speeds without intentional intervention by the user. Ability to discriminate between dynamic activities such as starts, stops, bumpy or inclined terrain and obstacle collisions will be determined. Usage patterns and measures of independence in the home and community will document the effects of the comprehensive control system. This translational project will establish the feasibility of a new intervention fr maximizing seated stability, facilitating personal mobility and enhancing the safety and functional independence of veterans with SCI, and in so doing define the most effective implementation for future clinical trials and widespread distribution throughout the VA healthcare system.
PUBLIC HEALTH RELEVANCE:
Spinal cord injury (SCI) significantly restricts access to life opportunities and compromises the ability to work, engage in social or leisure activities, and assume an independent and productive lifestyle. Activating the paralyzed hip and trunk muscles can promote healthy skeletal alignment, restore and maintain erect sitting postures, extend bimanual reach and the ability manipulate objects, prevent falls, improve the efficiency of manual wheelchair propulsion and facilitate transfers and other activities of daily living. This project is important because it specifies a comprehensive control system for restoring sitting posture and balance that can improve seated function by stiffening the trunk in task-dependent manners without conscious effort by the user. It is directly applicable to the health and well-being of disabled veterans who
are over-represented in the SCI population.
描述(由申请人提供):
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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RONALD J TRIOLO其他文献
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{{ truncateString('RONALD J TRIOLO', 18)}}的其他基金
Functional and Neuroprotective Effects of Restoring Lower Limb Sensation after Diabetic Peripheral Neuropathy
糖尿病周围神经病变后恢复下肢感觉的功能和神经保护作用
- 批准号:
10390351 - 财政年份:2021
- 资助金额:
-- - 项目类别:
Functional and Neuroprotective Effects of Restoring Lower Limb Sensation after Diabetic Peripheral Neuropathy
糖尿病周围神经病变后恢复下肢感觉的功能和神经保护作用
- 批准号:
10599863 - 财政年份:2021
- 资助金额:
-- - 项目类别:
Functional and Neuroprotective Effects of Restoring Lower Limb Sensation after Diabetic Peripheral Neuropathy
糖尿病周围神经病变后恢复下肢感觉的功能和神经保护作用
- 批准号:
10184521 - 财政年份:2021
- 资助金额:
-- - 项目类别:
Stimulation combined with externally powered motorized orthoses for stroke
刺激结合外部动力电动矫形器治疗中风
- 批准号:
10329995 - 财政年份:2020
- 资助金额:
-- - 项目类别:
Stimulation combined with externally powered motorized orthoses for stroke
刺激结合外部动力电动矫形器治疗中风
- 批准号:
10543078 - 财政年份:2020
- 资助金额:
-- - 项目类别:
Hybrid neuroprosthesis with power assist for walking in SCI
用于 SCI 行走的混合神经假体
- 批准号:
9768248 - 财政年份:2016
- 资助金额:
-- - 项目类别:
Exploiting Selective Recruitment to Prolong Standing after SCI
利用选择性招募来延长 SCI 后的资格
- 批准号:
9525331 - 财政年份:2013
- 资助金额:
-- - 项目类别:
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