Senior Research Career Scientist
Senior Research Career Scientist
批准号:
10672971
负责人:
RONALD J TRIOLO
金额:
$0.0万
依托单位国家:
美国
项目类别:
财政年份:
2021
资助国家:
美国
项目状态:
未结题
起止时间:
2021-10-01 至 2028-09-30
关键词:
AchievementAcuteAddressAdoptedAffectAmericanAmputationAmputeesAnimalsAnkleArchitectureArchivesAreaAwardBiomechanicsBiomedical EngineeringBook ChaptersCentral Nervous SystemChronicChronic DiseaseClinicalCollaborationsCommunitiesCommunity ParticipationContractsDedicationsDevelopmentDevicesDiabetes MellitusDisabled PersonsEducationElectrodesEmployeeEnvironmentEquilibriumEsthesiaEtiologyExerciseExhibitsFall preventionFatigueFemurFloorFundingGaitGait abnormalityHealthHealthcareHeartHospital CostsHumanImmobilizationImpairmentImplantIndividualInjuryInterventionIntuitionJointsJournalsKneeLaboratory StudyLegal patentLeisure ActivitiesLife StyleLimb ProsthesisLimb structureLocationLower ExtremityLungMalignant NeoplasmsManual wheelchairManualsManufacturerMechanicsMechanoreceptorsMediationMedicalMedical DeviceMedical StudentsMedical centerMedicineMentorsMethodsModalityMotionMotorMovementMulti-Institutional Clinical TrialMultiple SclerosisMuscleMuscle ContractionMusculoskeletal EquilibriumNamesNerveNeuromechanicsNeuromuscular DiseasesNeuronsOperative Surgical ProceduresOutputPaperParalysedParticipantPeer ReviewPelvisPerceptionPerformancePeripheralPeripheral NervesPersonal SatisfactionPhasePhysical MedicinePhysical RehabilitationPopulationPostdoctoral FellowPosturePreclinical TestingPrincipal InvestigatorProcessProductivityPsychophysicsPublicationsRampReactionRecurrenceRehabilitation therapyReportingResearchResearch PersonnelRiskSafetyScientistSelf-Help DevicesSeminalSensorySeriesServicesSiteSkinSocial isolationSpinal CordSpinal cord injuryStrokeSystemTechnologyTextbooksTissuesTranslationsTraumaUnited States Department of Veterans AffairsUnited States National Institutes of HealthUniversitiesVertebral columnVeteransVeterans Health AdministrationVisualWalkingWheelchair propulsionWheelchairsWorkbody systembonecareerclinical applicationclinical translationcomputerized toolscostdesigndiabeticdisabilityerectionexercise interventionexoskeletonexperiencefall injuryfallsfeasibility trialfirst-in-humanfootfunctional independencegraduate studentimprovedinnovationlimb lossneuralneural implantneural prosthesisneural stimulationneuroprosthesisnovelpreventprogramsrehabilitation researchresearch and developmentresidual limbsciatic nervesedentary lifestylesenior facultysocialspine bone structuresurgery outcometechnology platformtechnology/techniquetranslational frameworkunhealthy lifestylewalking speed
中文摘要
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英文摘要
Dr. Ronald J. Triolo is Senior Research Career Scientist with the Rehabilitation R&D Service, and a Tenured
Full Professor of Biomedical Engineering at Case Western Reserve University. He is Executive Director
of the VA RR&D Center for Advanced Platform Technology which develops novel medical devices and
assistive restorative technologies for individuals with sensorimotor impairments or limb loss. Dr. Triolo has
authored over 150 peer-reviewed publications and textbook chapters, and has mentored more than 40
graduate and medical students or post-doctoral trainees. He currently leads independent research programs
funded the VA, NIH, DoD and other agencies as Principal or Co-Principal Investigator. Dr. Triolo was inducted
into the American Institute for Medical and Biological Engineering, received the Paul B. Magnuson
Award for outstanding achievement in Rehabilitation Research and Development from the VA, and was
named the Outstanding Veterans Health Administration Employee (Honorable Mention) of 2020 by the
Disabled American Veterans (DAV). Dr. Triolo has devised, patented and evaluated assistive devices to
facilitate the sit-to-stand transition and negotiate stairs, ramps or other architectural barriers, and is in the
process of preparing novel interventions for exercising after spinal cord injury (SCI) for dissemination within the
VHA. His research program encompasses five main areas:
1. Implanted Neuroprostheses for Standing and Walking: Dr. Triolo leads an interdisciplinary team
dedicated to developing, deploying, and evaluating the clinical outcomes of surgically implanted motor system
neuroprostheses for lower extremity function after SCI. He quantifies their acute and chronic performances,
and explores novel methods of integrating stimulated and volitional muscle activity. His team creates new
computational tools to analyze the biomechanics of bipedal stance and stepping, and applies them to optimize
control systems for maintaining erect balance or facilitating efficient walking.
2. Seated Balance and Wheelchair Propulsion: This research explores methods to control the paralyzed
pelvis and spine to restore vertebral alignment, extend bimanual reach, provide active sitting balance, and
enhance mechanical efficiency of manual wheelchair propulsion. Dr. Triolo documents the effects of
modulating stiffness of the trunk on regulating upright posture to prevent falls from the wheelchair and expand
control over objects in the environment.
3. Selective Peripheral Nerve Interfaces: Dr. Triolo has designed and verified the safety and performance
of new, highly selective multicontact peripheral nerve electrodes capable of isolating functionally distinct
fascicular groups within a common nerve trunk. Selectivly activating of independent groups of neurons can
elicit multiple joint motions, or discrete sensations perceived as arising from the missing limb, from a common
surgical site on the proximal nerve, and alternating between synergistic motor unit pools can prolong force
output and delay onset of fatigue.
4. Natural Sensation for Lower Limb Amputees: This program applies selective multicontact nerve
electrodes to activate the sensory components of the sciatic nerve above the knee in the residual limbs of
amputees to induce sensations referred to the missing limb. Elicited sensory information is processed by the
CNS in a manner similar to input from intact mechanoreceptors, and can improve standing and ambulatory
ability after traumatic or diabetic limb loss, and is being integrating with motorized lower limb prostheses.
5. Neuromechanical Gait Assist Systems: Dr. Triolo develops novel exoskeletal systems to facilitate
bipedal mobility for individuals with SCI or other neuromuscular disorders. His innovative “muscle first”
approach integrates mechanical components with volitional or electrically activated muscle contractions to
maximize physical benefit and achieve the walking speeds required for community ambulation.
期刊论文(1)
专著(0)
科研奖励(0)
会议论文
Functional and Neuroprotective Effects of Restoring Lower Limb Sensation after Diabetic Peripheral Neuropathy
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批准号:10390351
-
项目类别:
-
资助金额:$0.0万
-
财政年份:2021
-
负责人:RONALD J TRIOLO
-
依托单位:
Functional and Neuroprotective Effects of Restoring Lower Limb Sensation after Diabetic Peripheral Neuropathy
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批准号:10599863
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项目类别:
-
资助金额:$0.0万
-
财政年份:2021
-
负责人:RONALD J TRIOLO
-
依托单位:
Functional and Neuroprotective Effects of Restoring Lower Limb Sensation after Diabetic Peripheral Neuropathy
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批准号:10184521
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项目类别:
-
资助金额:$0.0万
-
财政年份:2021
-
负责人:RONALD J TRIOLO
-
依托单位:
Senior Research Career Scientist
-
批准号:10315818
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项目类别:
-
资助金额:$0.0万
-
财政年份:2021
-
负责人:RONALD J TRIOLO
-
依托单位:
Senior Research Career Scientist
-
批准号:10507773
-
项目类别:
-
资助金额:$0.0万
-
财政年份:2021
-
负责人:RONALD J TRIOLO
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依托单位:
Stimulation combined with externally powered motorized orthoses for stroke
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批准号:10329995
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项目类别:
-
资助金额:$0.0万
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财政年份:2020
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负责人:RONALD J TRIOLO
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依托单位:
Stimulation combined with externally powered motorized orthoses for stroke
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批准号:10543078
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项目类别:
-
资助金额:$0.0万
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财政年份:2020
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负责人:RONALD J TRIOLO
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依托单位:
Hybrid neuroprosthesis with power assist for walking in SCI
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批准号:9768248
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项目类别:
-
资助金额:$0.0万
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财政年份:2016
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负责人:RONALD J TRIOLO
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依托单位:
A neuroprosthesis for seated posture and balance
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批准号:8486090
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项目类别:
-
资助金额:$0.0万
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财政年份:2013
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负责人:RONALD J TRIOLO
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依托单位:
Exploiting Selective Recruitment to Prolong Standing after SCI
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批准号:9525331
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项目类别:
-
资助金额:$0.0万
-
财政年份:2013
-
负责人:RONALD J TRIOLO
-
依托单位:
Exploiting Selective Recruitment to Prolong Standing after SCI
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批准号:9110739
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项目类别:
-
资助金额:$0.0万
-
财政年份:2013
-
负责人:RONALD J TRIOLO
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依托单位:
Exploiting Selective Recruitment to Prolong Standing after SCI
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批准号:8477853
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项目类别:
-
资助金额:$0.0万
-
财政年份:2013
-
负责人:RONALD J TRIOLO
-
依托单位:
A neuroprosthesis for seated posture and balance
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批准号:8990788
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项目类别:
-
资助金额:$0.0万
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财政年份:2013
-
负责人:RONALD J TRIOLO
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依托单位:
Long-term follow-up of implanted lower extremity neuroprostheses
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批准号:8196156
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项目类别:
-
资助金额:$0.0万
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财政年份:2012
-
负责人:RONALD J TRIOLO
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依托单位:
IMPLANTABLE NEUROPROSTHESIS FOR STANDING AND FUNCTIONAL MOBILITY IN SCI
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批准号:7378083
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项目类别:
-
资助金额:$3.41万
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财政年份:2006
-
负责人:RONALD J TRIOLO
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依托单位:
AMBULATION AFTER INCOMPLETE LOWER EXTREMITY PARALYSIS WITH FES
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批准号:7202733
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项目类别:
-
资助金额:$2.17万
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财政年份:2005
-
负责人:RONALD J TRIOLO
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依托单位:
IMPLANTABLE NEUROPROSTHESIS FOR STANDING AND FUNCTIONAL MOBILITY IN SCI
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批准号:7202806
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项目类别:
-
资助金额:$2.06万
-
财政年份:2005
-
负责人:RONALD J TRIOLO
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依托单位:
Implantable neuroprosthesis for standing and functional mobility in SCI
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批准号:6975012
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项目类别:
-
资助金额:$2.68万
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财政年份:2004
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负责人:RONALD J TRIOLO
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依托单位:
Tissue viability of paralyzed muscle using neuromuscular electrical stimulation
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批准号:6975015
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项目类别:
-
资助金额:$0.04万
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财政年份:2004
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负责人:RONALD J TRIOLO
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依托单位:
Enhancing Neuroprosthesis Performance with Nerve Cuff Electrodes
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批准号:7371648
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项目类别:
-
资助金额:$54.69万
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财政年份:2003
-
负责人:RONALD J TRIOLO
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依托单位:
海外基金