Diet quality and cardiometabolic disparities among Latino ethnic subgroups

拉丁裔族群之间的饮食质量和心脏代谢差异

• 批准号: 9108165
• 负责人: JOSIEMER MATTEI
• 金额: $ 14.16万
• 依托单位: HARVARD SCHOOL OF PUBLIC HEALTH
• 依托单位国家: 美国
• 财政年份: 2014
• 资助国家: 美国
• 起止时间: 2014-08-15 至 2019-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9108165
• 关键词: Accounting; Adult; Advisory Committees; Affect; Ankle; Area; Attitude; Behavior Therapy; Belief; Blood Pressure; Boston; Cardiovascular Diseases; Cardiovascular system; Central American; Chronic Disease; Clinic; Collaborations; Communities; Community Health Centers; Community Trial; Cuban American; Data; Diet; Diet Habits; Dietary Intervention; Disease; Doctor of Philosophy; Educational Intervention; Epidemiologic Methods; Epidemiology; Ethnic Origin; Ethnic group; Faculty; Food; Funding; Goals; Grant; Growth; Health; Healthy Eating; High Prevalence; Hispanic Community Health Study/Study of Latinos; Hispanics; Inflammatory; Institution; Interleukin-6; Intervention; Island; K-Series Research Career Programs; Knowledge; Latin America; Latino; Leadership; Life; Lipids; Longitudinal Studies; Mentors; Metabolic; Metabolic Diseases; Metabolic syndrome; Methods; Mexican; Minority Groups; Monitor; National Heart, Lung, and Blood Institute; Non-Insulin-Dependent Diabetes Mellitus; Nutritional; Obesity; Outcome; Participant; Perception; Pilot Projects; Population; Positioning Attribute; Prevalence; Public Health; Public Health Schools; Puerto Rican; Puerto Rico; Recruitment Activity; Research; Research Personnel; Research Training; Resources; Risk; Risk Factors; Role; Shapes; Solid; South American; Structure; Study of Latinos; Subgroup; Surface; TNF gene; Training; Training Programs; Translating; Translations; United States; Variant; Work; abstracting; aged; base; burden of illness; cardiometabolic risk; cardiovascular disorder risk; cardiovascular health; career; career development; cohort; community intervention; design; health disparity; improved; indexing; metabolic profile; nutrition; nutrition education; nutritional epidemiology; pilot trial; programs; racial and ethnic disparities; tool

DESCRIPTION (provided by applicant): The overall goal for this application for a NHLBI-K01 Faculty Diversity Mentored Career Development Award is to provide the candidate, Josiemer Mattei, PhD, MPH, with indispensable training to become an independent researcher in nutrition and cardio-metabolic disparities in Latinos, through epidemiological and intervention projects. These have been constructed along a comprehensive training program facilitated by a team of expert mentors in nutritional epidemiology, cardiovascular health, and community interventions. Responding to the staggering prevalence of cardiovascular disease (CVD) and other chronic disease in Latinos living in the United States (US), and to the limited studies on the dietary habits and cultural beliefs that may contribute to those disparities, the research aims are to (1) to identify diet quality indices within Latino ethnic subgroups in the US and to evaluate associations of such indices with traditional and emerging CVD risk factors within ethnicity, (2) to contrast diet quality of Puerto Ricans in the mainland US versus the island, and assess how it is associated with long-term cardio-metabolic factors; and (3) to assess deep-cultural factors (core beliefs and influences) related to diet and disease and determine efficacy of a pilot intervention based on such components for Latino subgroups on improving diet quality. Analyses for the first two aims will be conducted using data from the national Hispanic Community Health Study/Study of Latinos, the Boston Puerto Rican Health Study, and the San Juan Obese Adult Longitudinal Study in Puerto Rico. Latino multiethnic adults will be recruited for the mixed-methods formative and pilot studies to be conducted at the South End Community Health Center in Boston, MA. To match the scope of the proposed scientific work, this proposal includes five career-development and training areas: (1) research expertise through the proposed aims, (2) coursework in advanced epidemiological methods, and behavioral and community intervention methods, (3) multiple career-building activities to acquire essential tools for leadership and professional growth, as well as dissemination and translation of findings, (4) continued mentoring and monitoring by an outstanding team of senior mentors and an advisory committee; and (5) a detailed plan to expand grant support and collaborations with various national institutions. This K01 project will compellingly impact public health by bridging the gap in knowledge of traditional diet quality of specific Latino groups and how these may shape racial and ethnic disparities in CVD risk factors. The work will provide preliminary data to support longitudinal studies on diet and disease, and full-scale community trials on improving diet quality to reduce disease burden among Latinos. The project builds upon exceptional resources and mentoring at the candidate's institution (Harvard School of Public Health) and partnering organizations, to train her in key new areas, bolster applications for competitive funding, disseminate findings among researchers and the wider community, augment faculty diversity, and attain research independence. (End of Abstract)

描述（由申请人提供）：申请 NHLBI-K01 教师多样性指导职业发展奖的总体目标是通过流行病学和干预项目为候选人 Josiemer Mattei 博士、公共卫生硕士提供不可或缺的培训，使其成为拉丁裔营养和心脏代谢差异方面的独立研究员。这些是根据营养流行病学、心血管健康和社区干预方面的专家导师团队推动的综合培训计划构建的。 针对居住在美国 (US) 的拉丁裔中心血管疾病 (CVD) 和其他慢性疾病的惊人患病率，以及对可能导致这些差异的饮食习惯和文化信仰的研究有限，该研究的目的是 (1) 确定美国拉丁裔种族亚群的饮食质量指数，并评估这些指数与美国传统和新兴 CVD 风险因素的关联。 种族，(2) 对比美国大陆和岛上波多黎各人的饮食质量，并评估其与长期心脏代谢因素的关系； (3) 评估与饮食和疾病相关的深层文化因素（核心信念和影响），并确定基于此类成分的试点干预措施对拉丁裔亚群体改善饮食质量的效果。前两个目标的分析将使用来自全国西班牙裔社区健康研究/拉丁裔研究、波士顿波多黎各健康研究和波多黎各圣胡安肥胖成人纵向研究的数据进行。将招募拉丁裔多民族成年人参加在马萨诸塞州波士顿南端社区健康中心进行的混合方法形成性和试点研究。为了与拟议的科学工作范围相匹配，该提案包括五个职业发展和培训领域：(1) 通过拟议目标的研究专业知识，(2) 高级流行病学方法以及行为和社区干预方法的课程作业，(3) 多项职业建设活动，以获得领导力和专业发展的重要工具，以及研究结果的传播和翻译，(4) 由优秀的高级导师团队和 咨询委员会； (5) 扩大赠款支持以及与各国家机构合作的详细计划。该 K01 项目将弥合特定拉丁裔群体传统饮食质量的知识差距，以及这些知识如何影响 CVD 风险因素的种族和民族差异，从而对公共健康产生重大影响。这项工作将为支持饮食和疾病的纵向研究以及改善饮食质量的全面社区试验提供初步数据 减少拉丁裔的疾病负担。该项目以候选人所在机构（哈佛大学公共卫生学院）和合作组织的卓越资源和指导为基础，对她进行关键新领域的培训，支持竞争性资金的申请，在研究人员和更广泛的社区中传播研究结果，增强教师多样性，并实现研究独立性。 （摘要完）