Impact of drug use on HIV/STI risk across development among African American female adolescents: An integrative data analysis

吸毒对非洲裔美国女性青少年整个发展过程中艾滋病毒/性传播感染风险的影响：综合数据分析

• 批准号: 9320405
• 负责人: Andrea Swartzendruber
• 金额: $ 7.94万
• 依托单位: UNIVERSITY OF GEORGIA
• 依托单位国家: 美国
• 财政年份: 2015
• 资助国家: 美国
• 起止时间: 2015-09-01 至 2018-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9320405
• 关键词: Impact; drug; use; HIV; STI

 DESCRIPTION (provided by applicant): The overarching goal of the proposed research is to yield a more precise, developmental understanding of drug-related HIV and sexually transmitted infection (STI) risk among African American female adolescents in the Southern United States. The proposed study will use an integrative data analysis (IDA) approach to pool and harmonize existing data from 4 completed HIV/STI prevention trials conducted among African American female adolescents. IDA is a framework for conducting simultaneous analysis of data pooled from multiple studies. The study team will use an accelerated longitudinal design, a method for linking multiple cohorts by age, to assess developmental relationships between drug use and HIV/STI risk across adolescence. Specifically, the proposed research will 1) create a pooled data set with harmonized variables and corresponding codebook combining data from 4 HIV/STI prevention intervention trials conducted among African American female adolescents aged 14-24 years (N=2,243). The study will then use the pooled, harmonized dataset to: 2) examine the influence of drug use behaviors on the natural course of sexual risk behavior (e.g., multiple sexual partners, vaginal sex without a condom) across adolescent development; 3) examine the influence of drug use behaviors on the natural course of STI acquisition across adolescent development and 4) evaluate the extent to which HIV/STI prevention interventions reduce drug use behaviors across adolescent development. Findings from this research will be useful for advancing interventions to reduce drug-related HIV/STI risk among African American adolescent females in the South.



项目成果

Age-related associations between substance use and sexual risk behavior among high-risk young African American women in the South.

南方高危年轻非裔美国女性物质使用与性危险行为之间的年龄相关性。

• DOI: 10.1016/j.addbeh.2019.04.031
• 发表时间: 2019
• 期刊: Addictive behaviors
• 影响因子: 4.4
• 作者: Swartzendruber,Andrea;Brown,JenniferL;Sales,JessicaM;Windle,Michael;Haardörfer,Regine
• 通讯作者: Haardörfer,Regine

Developmental Changes in Sexual Risk and Substance Use Among African American Females: an Integrated Data Analysis Approach Using Time-varying Effect Models.

非裔美国女性性风险和药物使用的发展变化：使用时变效应模型的综合数据分析方法。

• DOI: 10.1007/s11121-019-01046-w
• 发表时间: 2020
• 期刊: Prevention science : the official journal of the Society for Prevention Research
• 作者: Swartzendruber,Andrea;Brown,JenniferL;Sales,JessicaM;DiClemente,RalphJ;Windle,Michael;Haardörfer,Regine
• 通讯作者: Haardörfer,Regine