Sixth Annual Aspen Brain Forum: The Addicted Brain and New Treatment Frontiers

第六届阿斯本大脑论坛：成瘾的大脑和新的治疗前沿

• 批准号: 9125695
• 负责人: Peter W Kalivas
• 金额: $ 2.5万
• 依托单位: NEW YORK ACADEMY OF SCIENCES
• 依托单位国家: 美国
• 财政年份: 2016
• 资助国家: 美国
• 起止时间: 2016-06-01 至 2017-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9125695
• 关键词: Academia; Academy; Addictive Behavior; Address; Adolescence; Adolescent; Alcohol or Other Drugs use; Area; Award; Behavior; Behavior Therapy; Behavior monitoring; Behavioral; Brain; Brain Diseases; Caring; Clinical; Clinical Data; Clinical Investigator; Collaborations; Communication; Communities; Congresses; Consensus; Criminal Justice; Cues; Deep Brain Stimulation; Development; Disabled Persons; Disease; Drug Industry; Economics; Educational workshop; Emotions; Environment; Event; Faculty; Fellowship; Female; Fostering; Foundations; Future; Genetic; Geographic state; Goals; Government; Health Services Accessibility; Health system; Healthcare Systems; Immune; Individual; Industry; International; Intervention; Journals; Knowledge; Laws; Life; Medical Research; Mentors; Methods; Minority; Mission; Molecular; Multimedia; Naltrexone; National Institute of Drug Abuse; Neurobiology; Neuronal Plasticity; Neurosciences; New York; New York City; Oral; Participant; Pathway interactions; Pharmaceutical Preparations; Pharmacogenetics; Pharmacologic Substance; Pharmacological Treatment; Physicians; Policies; Prevention; Process; Public Health; Public Policy; Publications; Publishing; Reporting; Research; Research Personnel; Science; Scientist; Societies; Specialist; Stimulus; Substance Addiction; Technical Expertise; Technology; Therapeutic; Translational Research; Translations; Travel; Underrepresented Minority; United States; United States Food and Drug Administration; Woman; abstracting; addiction; alcohol use disorder; base; brain circuitry; career; cocaine use; coping; cost; data exchange; discount; disturbance in affect; executive function; frontier; improved; individualized medicine; innovation; learned behavior; lectures; marijuana legalization; marijuana use disorder; meetings; methamphetamine use; minority investigator; negative mood; neural circuit; neurobiological mechanism; neurodevelopment; new therapeutic target; novel; novel therapeutics; open data; posters; public health relevance; racial minority; reduced substance abuse; repository; response; reward anticipation; social; socioeconomics; symposium; translational medicine; treatment strategy; varenicline

 DESCRIPTION: Although research advances in neural circuitry and behavior have improved our understanding of the processes underlying addiction, gaps remain in the development of new biologic or pharmacologic therapies, neuroscience-based behavioral treatment and monitoring methods, and access-to-care strategies. To address these unmet needs, the New York Academy of Sciences, together with the Aspen Brain Forum Foundation, and the journal Science Translational Medicine will present a 2.5-day conference titled, "Sixth Annual Aspen Brain Forum: The Addicted Brain and New Treatment Frontiers," on May 18 - 20, 2016, in New York City. This conference will convene approximately 250 attendees - including basic scientists and clinical investigators in academia, industry, and government; physicians and other addiction treatment specialists; pharmaceutical strategists; and lawmakers - in an effort to better understand the neurobiology of addiction. The event will include discussions on neuroplasticity, neurodevelopment, and socio-political issues, with the goals of developing new targets and improving current behavioral and pharmacological treatments. The three central aims of this conference are to: (i) provide a neutral forum through lectures, a keynote presentation, interactive debates, and networking activities for discussing the neurobiological landscape of addiction, therapeutic prospects, and the socio-political environment within which addiction persists; (ii) showcase and encourage the participation of early career, female, and underrepresented minority investigators via short talks, poster presentations, travel fellowships, career mentoring activities, and discounted registration; and (iii) foster collaboration among international investigators from all sectors to promote the translation of research into more effective addiction therapeutics. The conference goals align well with the mission of the National Institute on Drug Abuse (NIDA) to support the advancement of new knowledge on the neurobiological and behavioral processes underlying addictive behaviors, and the translation of information into interventions that may ultimately reduce substance abuse. In addition, NIDA's specific goal of disseminating information about addiction and advances in research will be met through the publication of a post-conference, enduring, open-access, Section 508- compliant Meeting Report in Annals of the New York Academy of Sciences and an online, multimedia report known as an eBriefing, which will distribute the scientific knowledge and ideas exchanged at the meeting to the global research and medical communities. This conference is especially timely given recent advances in neurobiology research and changes to substance laws (e.g., expanded legalization of marijuana usage within many U.S. states and efforts to reform drug criminalization policies). A collaborative examination of this new information among all addiction stakeholders is of significant value for guiding research forward in the field - particularly with respect to potential innovative therapeutic approaches.

 描述：尽管神经元电路和行为的研究进展提高了我们对成瘾过程的理解，但差距仍在开发新的生物学或药物治疗，基于神经科学的行为治疗和监测方法以及访问护理策略中。为了满足这些未满足的需求，纽约科学院与阿斯彭大脑论坛基金会以及《科学转化医学》杂志将于2016年5月18日至20日在纽约市举行2次为期2.5天的会议，标题为“第六届年度Aspen Brain Forum：上瘾的大脑和新治疗前沿”。这次会议将简短简短，包括250名与会者 - 包括学术界，工业和政府的基础科学家和临床研究人员；医师和其他成瘾治疗专家；药物策略；和立法者 - 为了更好地了解成瘾的神经生物学。该活动将包括有关神经塑性，神经发育和社会政治问题的讨论，以及开发新目标并改善当前行为和药物治疗的目标。这次会议的三个中心目的是：（i）通过讲座，主题演讲，互动辩论和网络活动提供中性论坛，以讨论成瘾的神经生物学格局，理论前景和社会政治环境的成瘾持续存在； （ii）通过简短的演讲，海报演示，旅行奖学金，职业心理活动和折扣注册来展示和鼓励早期职业，女性和代表性不足的少数民族调查员的参与； （iii）促进来自所有部门的国际研究人员之间的合作，以促进研究对更有效的成瘾疗法的翻译。会议目标与美国国家药物滥用研究所（NIDA）的使命相吻合，以支持关于神经生物学和行为过程的新知识的发展，并将信息转化为干预措施，这些干预措施最终可能会减少药物滥用。此外，NIDA通过在纽约科学院和在线，多媒体学院的年鉴中发表会议，持久的，持久的开放式，第508节的会议报告来实现有关成瘾和研究进展的信息的具体目标。鉴于神经生物学研究的最新进展和物质法律的变化（例如，美国许多州内大麻使用的扩展遗产以及改革药物犯罪政策的努力），这次会议尤其及时。在所有成瘾利益相关者中，对这些新信息的合作检查对于指导该领域的研究具有重要价值，尤其是在潜在的创新治疗方法方面。