Sixth Annual Aspen Brain Forum: The Addicted Brain and New Treatment Frontiers

第六届阿斯本大脑论坛：成瘾的大脑和新的治疗前沿

• 批准号: 9125695
• 负责人: Peter W Kalivas
• 金额: $ 2.5万
• 依托单位: NEW YORK ACADEMY OF SCIENCES
• 依托单位国家: 美国
• 财政年份: 2016
• 资助国家: 美国
• 起止时间: 2016-06-01 至 2017-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9125695
• 关键词: Academia; Academy; Addictive Behavior; Address; Adolescence; Adolescent; Alcohol or Other Drugs use; Area; Award; Behavior; Behavior Therapy; Behavior monitoring; Behavioral; Brain; Brain Diseases; Caring; Clinical; Clinical Data; Clinical Investigator; Collaborations; Communication; Communities; Congresses; Consensus; Criminal Justice; Cues; Deep Brain Stimulation; Development; Disabled Persons; Disease; Drug Industry; Economics; Educational workshop; Emotions; Environment; Event; Faculty; Fellowship; Female; Fostering; Foundations; Future; Genetic; Geographic state; Goals; Government; Health Services Accessibility; Health system; Healthcare Systems; Immune; Individual; Industry; International; Intervention; Journals; Knowledge; Laws; Life; Medical Research; Mentors; Methods; Minority; Mission; Molecular; Multimedia; Naltrexone; National Institute of Drug Abuse; Neurobiology; Neuronal Plasticity; Neurosciences; New York; New York City; Oral; Participant; Pathway interactions; Pharmaceutical Preparations; Pharmacogenetics; Pharmacologic Substance; Pharmacological Treatment; Physicians; Policies; Prevention; Process; Public Health; Public Policy; Publications; Publishing; Reporting; Research; Research Personnel; Science; Scientist; Societies; Specialist; Stimulus; Substance Addiction; Technical Expertise; Technology; Therapeutic; Translational Research; Translations; Travel; Underrepresented Minority; United States; United States Food and Drug Administration; Woman; abstracting; addiction; alcohol use disorder; base; brain circuitry; career; cocaine use; coping; cost; data exchange; discount; disturbance in affect; executive function; frontier; improved; individualized medicine; innovation; learned behavior; lectures; marijuana legalization; marijuana use disorder; meetings; methamphetamine use; minority investigator; negative mood; neural circuit; neurobiological mechanism; neurodevelopment; new therapeutic target; novel; novel therapeutics; open data; posters; public health relevance; racial minority; reduced substance abuse; repository; response; reward anticipation; social; socioeconomics; symposium; translational medicine; treatment strategy; varenicline

 DESCRIPTION: Although research advances in neural circuitry and behavior have improved our understanding of the processes underlying addiction, gaps remain in the development of new biologic or pharmacologic therapies, neuroscience-based behavioral treatment and monitoring methods, and access-to-care strategies. To address these unmet needs, the New York Academy of Sciences, together with the Aspen Brain Forum Foundation, and the journal Science Translational Medicine will present a 2.5-day conference titled, "Sixth Annual Aspen Brain Forum: The Addicted Brain and New Treatment Frontiers," on May 18 - 20, 2016, in New York City. This conference will convene approximately 250 attendees - including basic scientists and clinical investigators in academia, industry, and government; physicians and other addiction treatment specialists; pharmaceutical strategists; and lawmakers - in an effort to better understand the neurobiology of addiction. The event will include discussions on neuroplasticity, neurodevelopment, and socio-political issues, with the goals of developing new targets and improving current behavioral and pharmacological treatments. The three central aims of this conference are to: (i) provide a neutral forum through lectures, a keynote presentation, interactive debates, and networking activities for discussing the neurobiological landscape of addiction, therapeutic prospects, and the socio-political environment within which addiction persists; (ii) showcase and encourage the participation of early career, female, and underrepresented minority investigators via short talks, poster presentations, travel fellowships, career mentoring activities, and discounted registration; and (iii) foster collaboration among international investigators from all sectors to promote the translation of research into more effective addiction therapeutics. The conference goals align well with the mission of the National Institute on Drug Abuse (NIDA) to support the advancement of new knowledge on the neurobiological and behavioral processes underlying addictive behaviors, and the translation of information into interventions that may ultimately reduce substance abuse. In addition, NIDA's specific goal of disseminating information about addiction and advances in research will be met through the publication of a post-conference, enduring, open-access, Section 508- compliant Meeting Report in Annals of the New York Academy of Sciences and an online, multimedia report known as an eBriefing, which will distribute the scientific knowledge and ideas exchanged at the meeting to the global research and medical communities. This conference is especially timely given recent advances in neurobiology research and changes to substance laws (e.g., expanded legalization of marijuana usage within many U.S. states and efforts to reform drug criminalization policies). A collaborative examination of this new information among all addiction stakeholders is of significant value for guiding research forward in the field - particularly with respect to potential innovative therapeutic approaches.

 描述：尽管神经回路和行为方面的研究进展提高了我们对成瘾背后过程的理解，但在新的生物或药物疗法、基于神经科学的行为治疗和监测方法以及获得护理策略的开发方面仍然存在差距。为了满足这些未满足的需求，纽约科学院与阿斯本大脑论坛基金会和《科学转化医学》杂志将于 2016 年 5 月 18 日至 20 日在纽约市举办为期 2.5 天的会议，题为“第六届年度阿斯本大脑论坛：成瘾大脑和新治疗前沿”。本次会议将召集约 250 名与会者，包括学术界、工业界和政府的基础科学家和临床研究人员；医生和其他成瘾治疗专家；医药策略师；和立法者 - 努力更好地理解成瘾的神经生物学。该活动将包括关于神经可塑性、神经发育和社会政治问题的讨论，目标是开发新的靶点并改进当前的行为和药物治疗。本次会议的三个中心目标是：（i）通过讲座、主题演讲、互动辩论和网络活动提供一个中立的论坛，讨论成瘾的神经生物学景观、治疗前景以及成瘾持续存在的社会政治环境； (ii) 通过简短演讲、海报展示、旅行奖学金、职业指导活动和折扣注册，展示并鼓励早期职业、女性和代表性不足的少数族裔调查员的参与； (iii) 促进各个部门的国际研究人员之间的合作，以促进研究成果转化为更有效的成瘾疗法。此次会议的目标与国家药物滥用研究所 (NIDA) 的使命高度契合，即支持推动成瘾行为背后的神经生物学和行为过程的新知识的发展，并将信息转化为最终可能减少药物滥用的干预措施。此外，NIDA 传播有关成瘾和研究进展的信息的具体目标将通过在《纽约科学院年鉴》中发布一份符合第 508 条规定的会后、持久、开放获取的会议报告和一份称为 eBriefing 的在线多媒体报告来实现，该报告将向全球研究和医学界分发会议上交流的科学知识和想法。鉴于神经生物学研究的最新进展和物质法的变化（例如，美国许多州扩大大麻使用合法化以及改革毒品刑事定罪政策的努力），这次会议显得尤为及时。所有成瘾利益相关者对这一新信息的合作检查对于指导该领域的研究具有重要价值 - 特别是在潜在的创新治疗方法方面。