Transplant Surgery Scientist Training Program

描述（由申请人提供）：移植有望逆转数千名患有终末期器官疾病以及代谢疾病的美国人的临床病程。西北大学的移植项目在临床移植和移植相关研究方面都处于全国领先地位。近年来，从事移植相关研究的移植外科医生和内科医生的人数有所减少。缺乏从事研究相关职业的积极性的原因包括：1）研究培训的财政支持不足，2）临床专业和超专业培训与研究培训之间的冲突，3）严格的研究方法学教学不足，和4）的方法项目主任缺乏问责制，无法确保致力于临床研究职业的受训人员参与他们在研究培训期间的活动，提高他们的竞争力，以获得独立的资金，当他们成为教师。该培训补助金的具体目标是：1）为受训者提供津贴支持; 2）由初级、中级和高级研究人员与精通移植的学术临床医生合作提供指导; 3）保护受训者免受争夺其时间的临床活动的影响; 4）维持一个扩大候选人库的种族多样性和质量的行政结构; 5）提供培训机会， 从基础/转化科学到与临床移植交叉的临床/结果研究的范围;以及6）继续进行评估过程，以确定该计划是否符合其目标和目的。学员将接触到成功进行移植相关研究所需的学科的课堂学习的严格基础，同时接触到移植手术的其他各个方面。有两个不同的轨道学员可以选择：NUTORC（西北大学移植成果研究协作）和NUCTRIBE（西北大学免疫生物学和生物医学工程移植研究协作）。两者都提供密集，严格的培训，由多学科的高级，中级和初级导师，以及课堂教育。NUTORC学员可以选择卫生服务和成果研究的MS，临床研究的MS，流行病学和生物统计学的MS或医疗质量和患者安全的MS。NUCTRIBE学员可以选择与他们的研究相关的许多学科的课程，在咨询和他们的导师和执行委员会批准后选择。这两个轨道都需要采取课程在负责任的研究行为。这两个轨道独特的准备学员进行创新，在移植相关领域的最先进的研究。

DESCRIPTION (provided by applicant): Transplantation holds the promise of reversing the clinical course of thousands of Americans afflicted with end- stage organ disease, as well as metabolic diseases. Northwestern University's transplant program is a national leader in both clinical transplantation and transplantation-related research. The number of transplant surgeons and physicians engaged in transplantation-related research had decreased in recent years. Reasons given for the lack of enthusiasm in pursuing a research-related career include 1) insufficient financial support for research training, 2) conflict between clinical specialty and su-specialty training and research training, 3) inadequate teaching of rigorous research methodology, and 4) the lack of accountability on the part of program directors to ensure that trainees committed to careers in clinical investigation are engaged in activities during their research training that enhance their competitiveness to obtain independent funding when they become faculty members. The specific objectives of this training grant are to 1) provide stipend support for trainees; 2) provide mentorship by junior, mid-level, and senior investigators in collaboration with academic clinicians well versed in transplantation; 3) protect trainees from clinical activities that compete for their time; 4) sustain an administrative structure that expand the ethnic diversity and quality of the candidate pool; 5) provide training opportunities that span the spectrum from both basic/translational science to clinical/outcomes research at their intersection with clinical transplantation; and 6) continue an ongoing evaluation process for determining whether or not the program is meeting its goals and objectives. Trainees will be exposed to a rigorous base of classroom study in the disciplines necessary for successfully conducting transplant-related research, while being exposed to various other aspects of transplant surgery. There are two different tracks trainees can select from: NUTORC (the Northwestern University Transplant Outcomes Research Collaborative) and NUCTRIBE (the Northwestern University Collaborative for Transplant Research in Immunobiology and Biomedical Engineering). Both provide intensive, rigorous training by multidisciplinary senior, mid-level, and junior mentors, as well as classroom education. NUTORC trainees may choose between an MS in Health Services and Outcomes Research, an MS in Clinical Investigation, an MS in Epidemiology and Biostatistics or an MS in Healthcare Quality and Patient Safety. NUCTRIBE trainees may select coursework from many disciplines related to their research, chosen after consultation and approval by their mentors and the Executive Committee. Both tracks are required to take coursework in the responsible conduct of research. Both tracks uniquely prepare trainees to perform innovative, state-of-the-art research in transplant-related fields.