Phase IIB: Portable Device for Telecare Monitoring of Elderly People

第二阶段：用于老年人远程护理监控的便携式设备

• 批准号: 9118830
• 负责人: Joseph T Gwin
• 金额: $ 73.98万
• 依托单位: BIOSENSICS, LLC
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-04-15 至 2018-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9118830
• 关键词: Accelerometer; Age; Aging; Algorithms; Arizona; Assisted Living Facilities; Clinical; Clinical Research; Clinical Trials; Clinical effectiveness; Clinics and Hospitals; Collaborations; Communities; Computer software; Data; Detection; Devices; Diagnosis; Early Diagnosis; Early Intervention; Elderly; Engineering; Equilibrium; Evaluation; Fall prevention; Family member; Feedback; Gait; Goals; Gold; Health; Home environment; Hour; Internet; Intervention; Interview; Legal patent; Life; Longevity; Manuscripts; Marketing; Measurement; Measures; Medical; Methods; Mind; Monitor; Motion; Motor; Nature; Outcome; Pattern; Peer Review; Performance; Pharmaceutical Preparations; Pharmacologic Substance; Phase; Physical Function; Physical activity; Physiological; Population; Quality of life; Recruitment Activity; Rehabilitation therapy; Research; Risk; Risk Assessment; Safety; Sensitivity and Specificity; Small Business Technology Transfer Research; Syndrome; System; Technology; Testing; Titrations; Universities; Walking; Work; abstracting; age related; base; commercialization; comparative; consumer product; cost; design; environmental change; fall risk; falls; field study; frailty; improved; interest; loved ones; non-compliance; novel; peace; screening; sensor; signal processing; telecare; telehealth; tool; wearable technology

 DESCRIPTION (provided by applicant): We propose to further develop, field test, and commercialize a reliable and robust sensor technology that allows the objective assessment of daily physical activity, risk of falling, frailty, and activity organization among older adults in he home and community. This is a Phase IIB STTR application. During Phases I&II BioSensics, LLC, in collaboration with the Interdisciplinary Consortium on Advanced Motion Performance and the Arizona Center on Aging at the University of Arizona, developed and clinically validated sophisticated signal processing algorithms and associated sensor hardware to monitor physical activity and falls in older adults using a single motion sensor (tri-axial accelerometer) worn on the torso or as a pendant. Our Phase I/II work resulted in two commercially available products. PAMSys(tm) is a wearable sensor platform for long-term monitoring of activity related parameters that are of significant importance for objective assessment of physical activity, functioning, frailty, and fall risk of older adults. PAMSys(tm) is primarily a research tool with broad applicatons in pharmaceutical clinical trials and other comparative outcomes clinical research. ActivePERS(tm) is a low-cost medical alert pendant with automatic fall detection, activity monitoring, and non-compliance alerts. ActivePERS(tm) is a consumer product that has been commercialized through 9 on-going partnerships with companies in the telehealth and medical alert markets. With this Phase IIB project we propose to improve our ActivePERS(tm) technology to enable long-term remote monitoring of fall risk and frailty status. An objective method for earl diagnosis, intervention and remote monitoring of the risk of falling/frailty using physical activit telemonitoring and feedback has not yet been developed. Such technology could be used to identify patterns indicative of early changes allowing early diagnosis and intervention of at-risk elders. In addition, it will enable remote and continuous screening of the risk of falling/frailty during daily life, supporting autonomy and quality of life, and limiting the need for clinical intervention. Moreover, the technology can provide an objective tool to evaluate the effects of rehabilitation on motor function, and hence on reductions in the risk of falling/frailty based on te relative efficacy of different interventions. There is a significant commercialization potential fo the proposed technology due to 1) the size of the market, 2) the disruptive nature of our first-to-market technology, and 3) the ongoing national push towards increased efforts towards fall prevention. We will have a market-ready device by the completion of this project with plans for a market launch during Phase III.

 描述（由申请人提供）：我们建议进一步开发、现场测试和商业化一种可靠且稳健的传感器技术，该技术允许客观评估家中和社区中老年人的日常身体活动、跌倒风险、虚弱和活动组织。这是IIB期STTR申请。在第一阶段和第二阶段，BioSensics，LLC与跨学科先进运动性能联盟和亚利桑那大学亚利桑那老龄化中心合作，开发并临床验证了复杂的信号处理算法和相关的传感器硬件，以监测身体活动和老年人的福尔斯，使用单个运动传感器（三轴加速度计）佩戴在躯干上或作为吊坠。我们的I/II期工作产生了两种商业可用的产品。PAMSys（TM）是一种可穿戴传感器平台，用于长期监测活动相关参数，这些参数对于客观评估老年人的身体活动、功能、虚弱和跌倒风险至关重要。PAMSys（TM）主要是一种研究工具，在药物临床试验和其他比较结果临床研究中具有广泛的应用。ActivePERS（TM）是一种低成本的医疗警报挂件，具有自动跌倒检测、活动监测和违规警报功能。ActivePERS（TM）是一种消费产品，已通过9个正在进行的合作伙伴关系，在远程医疗和医疗警报市场的公司商业化。在这个IIB阶段项目中，我们建议改进我们的ActivePERS（TM）技术，以实现对跌倒风险和虚弱状态的长期远程监控。尚未开发出使用身体活动远程监测和反馈对跌倒/虚弱风险进行诊断、干预和远程监测的客观方法。这种技术可用于识别早期变化的模式，从而为高危老年人提供早期诊断和干预。此外，它还将实现日常生活中跌倒/虚弱风险的远程和连续筛查，支持自主性和生活质量，并限制临床干预的需求。此外，该技术可以提供一种客观的工具来评估康复对运动功能的影响，从而根据不同干预措施的相对疗效来评估跌倒/虚弱风险的降低。由于1）市场的规模，2）我们的第一个市场技术的破坏性，以及3）国家正在推动增加预防跌倒的努力，因此拟议技术具有巨大的商业化潜力。在本项目完成时，我们将拥有一种市场就绪的器械，并计划在第三阶段上市。