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12th and 13th International Symposia on Neurobiology and Neuroendocrinology of Ag

第12届和第13届银神经生物学和神经内分泌学国际研讨会

基本信息

批准号：
9058973
负责人：
HOLLY M. BROWN-BORG
金额：
$ 2.96万
依托单位：
UNIVERSITY OF NORTH DAKOTA
依托单位国家：
美国
项目类别：
财政年份：
2014
资助国家：
美国
起止时间：
2014-05-01 至 2017-04-30
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/9058973
关键词：
Address Aging Alzheimer&apos s Disease Area Austria Biology of Aging Cell Aging Cell Therapy Clinical Collaborations Communication Comorbidity DNA Damage Disease Environment Epigenetic Process Faculty Funding Geriatrics Gerontology HIV Health Hormonal Insulin-Like Growth Factor I International Left Leptin Longevity Mitochondria Modeling Molecular Biology Myocardium Nerve Degeneration Neuraxis Neurobiology Neurocognitive Deficit Neurodegenerative Disorders Neuroendocrinology Neurons Oral Participant Positioning Attribute Postdoctoral Fellow Publishing Request for Applications Request for Proposals Research Research Personnel Role Science Scientist Senior Scientist Skin Slide System Technology Time Training Translations United States abstracting age related body system graduate student humanized mouse immunosenescence interest lectures meetings neuroprotection novel posters student conference symposium

项目摘要

DESCRIPTION (provided by applicant): The Twelfth and Thirteenth International Symposia on Neurobiology and Neuroendocrinology Aging will be held in Bregenz, Austria July 27-August 1, 2014 and in July 2016. The purpose of these meetings is to bring together a group of investigators who made recent significant advances in the study of mechanisms of aging, with particular emphasis on CNS aging, neuroprotection and treatment of neurodegenerative disease. Specific topics will include the diverse roles of IGF-1 in health span and lifespan and the interplay of IGF-1 and leptin in neuroprotection. Several lectures focus on diverse aspects of neurodegeneration including cell- based therapies, the environment and epigenetics, DNA damage, and mitochondrial sensitivity plus one that merges multiple models to understand neurodegeneration. Four lectures will specifically address recent advances in cellular senescence and age-related disease. An exciting new area of aging will be the focus of a group of presentations on HIV. These talks will focus on HIV and neurocognitive impairment, comorbidities, immunosenescence and the humanized mouse system. Discussion of mechanisms specifically related to aging of organ systems (heart, muscle, skin) will occupy another set of lectures. We purposely include a wide range of topics and assemble a group of scientists that may not normally attend the same meeting. The format of the meeting is modeled after Gordon Research Conferences and encourages formal and informal discussions of the material presented. Proceedings will be published as a special issue of Experimental Gerontology as has been done for the last 11 Symposia. Participation of junior investigators, including graduate students and post-doctoral fellows is strongly encouraged and this proposal seeks funds for providing stipends to those US participants who are in training or are in junior faculty positions and who are planning to present their findings in the poster session. We are also seeking partial support for the expenses of invited speakers from the United States.

说明（由申请人提供）：第十二届和第十三届神经生物学和神经内分泌衰老国际研讨会将于 2014 年 7 月 27 日至 8 月 1 日和 2016 年 7 月在奥地利布雷根茨举行。这些会议的目的是汇集一组在衰老机制研究方面取得最新重大进展的研究人员，特别是中枢神经系统衰老、神经保护和治疗。神经退行性疾病。具体主题将包括 IGF-1 在健康寿命和寿命中的不同作用以及 IGF-1 和瘦素在神经保护中的相互作用。几场讲座重点关注神经退行性疾病的各个方面，包括基于细胞的疗法、环境和表观遗传学、DNA 损伤和线粒体敏感性，以及融合多种模型以理解神经退行性疾病的讲座。四场讲座将专门讨论细胞衰老和年龄相关疾病的最新进展。一个令人兴奋的老龄化新领域将成为一组有关艾滋病毒的演讲的焦点。这些演讲将重点关注艾滋病毒和神经认知障碍、合并症、免疫衰老和人源化小鼠系统。与器官系统（心脏、肌肉、皮肤）老化具体相关的机制的讨论将占据另一组讲座的时间。我们特意涵盖了广泛的主题，并聚集了一组通常不会参加同一会议的科学家。会议的形式模仿戈登研究会议，鼓励对所提交的材料进行正式和非正式的讨论。与过去 11 届研讨会一样，会议记录将作为实验老年学特刊出版。强烈鼓励包括研究生和博士后研究员在内的初级研究人员的参与，该提案寻求资金为那些正在接受培训或担任初级教职人员并计划在海报会议上展示其发现的美国参与者提供津贴。我们还寻求对来自美国的受邀演讲者的费用提供部分支持。