2015 Salivary Glands and Exocrine Biology Gordon Research Conference

2015年唾液腺与外分泌生物学戈登研究会议

• 批准号: 8830753
• 负责人: Deborah J Andrew
• 金额: $ 2.2万
• 依托单位: GORDON RESEARCH CONFERENCES
• 依托单位国家: 美国
• 财政年份: 2015
• 资助国家: 美国
• 起止时间: 2015-01-01 至 2015-12-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8830753
• 关键词: Academy; Address; Affect; Animal Model; Animals; Anti-Bacterial Agents; Antifungal Agents; Area; Autoimmune Diseases; Automobile Driving; Bacterial Infections; Benign; Biological; Biological Models; Biology; Calcium; Calculi; Cells; Cellular biology; Clinical; Collaborations; Deglutition; Dental; Dental caries; Development; Digestion; Disease; Drosophila melanogaster; Duct (organ) structure; Electrolytes; Ensure; Environment; Epithelial; Etiology; Event; Exocrine Glands; Food Processing; Future; Gene Expression Profiling; Genes; Gland; Goals; Head and Neck Part; Head and neck structure; Health; Health Policy; Homeostasis; Human; Image; Individual; Invertebrates; Knowledge; Lacrimal gland structure; Lead; Learning; Lubrication; Lung; Maintenance; Malignant Neoplasms; Malignant neoplasm of salivary gland; Mammary gland; Mastication; Microbe; Mission; Modeling; Molecular; Morbidity - disease rate; Morphogenesis; Mucins; Mycoses; Natural regeneration; Oral; Oral cavity; Oral health; Organ; Pain; Pancreas; Parotid Gland; Pathway interactions; Physiological; Physiology; Postdoctoral Fellow; Primordium; Proteins; Quality of life; Radiation therapy; Request for Applications; Research; Research Personnel; Research Training; Risk; Role; Saliva; Salivary; Salivary Gland Diseases; Salivary Glands; Salivary duct structure; Schedule; Scientist; Secretory Cell; Secretory Vesicles; Sialadenitis; Sialolithiasis; Signal Transduction; Site; Sjogren' s Syndrome; Structure; Swelling; System; Technology; Texas; Time; Tissues; Tubular formation; Undifferentiated; Virus Diseases; Water; Work; abstracting; antimicrobial drug; career; cell type; craniofacial; cystatin As; design; experience; genome-wide; graduate student; histidine-rich proteins; improved; in vivo; insight; interest; intravital imaging; meetings; member; organ growth; posters; professor; programs; public health relevance; repaired; symposium

DESCRIPTION (provided by applicant): This application requests partial support for the tenth Gordon Research Conference on "Salivary Glands and Exocrine Biology" entitled "Development, homeostasis and repair of secretory organs: their microenvironments and the signals that control them" to be held February 15-20, 2015 at the Hotel Galvez, Galveston, TX. This meeting focuses on the formation, maintenance, function and repair of secretory organs. Talks will cover a range of model systems from invertebrate secretory glands to the professional secretory organs of higher animals, including the pancreas, gut, lungs, lacrimal, mammary, and salivary glands. Several exciting sessions are planned that will cover design principles underlying salivary gland and secretory organ development, recent advances in secretory cell biology, the role of mucins and other secretory cargo in epithelial organs, the machinery and circuitry regulating secretion, the role of secretion in host-microbe interactions, secretory organ diseases, and, finally, recent advances in the regeneration and repair of secretory organs. One session is dedicated to recent technological advances in imaging, gene editing and genome-wide approaches to understanding secretory biology. The meeting provides a unique setting bringing together basic scientists and clinicians from around the world working on the salivary gland and other exocrine organs. The relatively isolated meeting site at which all meals are shared will provide ample time to develop critical liaisons between experienced and new researches, between clinicians and basic scientists, and among individuals addressing a range of biological questions with a variety of approaches. Salivary function is essential to our abilityto process food, talk and protect our oral cavity from the bacterial and fungal infections that lead t tooth decay and other oral health problems. The goal of this meeting is to accelerate progress in research in salivary gland and exocrine gland biology with the ultimate goal of discovering better therapies for treating salivary gland and exocrine organ diseases. To achieve this goal, many experts in secretory organ biology have been invited to give oral presentations at this meeting and all attendees will be encouraged to present recent findings in afternoon poster sessions. The oral presentation schedule will also include shorter talks to be selected from the poster abstracts. This will ensure that recent exciting discoveries are presented at the meeting and that many younger people will be speaking. Overall, the goals of this meeting fit well with the NIDCR's mission to "improve oral, dental and craniofacial health through research, research training, and the dissemination of health information". In particular, this meeting will promote th sharing of knowledge obtained from recent studies in secretory organ biology to ultimately guide oral health policies and disease treatment.

申请者描述(申请人提供)：本申请请求部分支持将于2015年2月15-20日在德克萨斯州加尔维斯顿的加尔韦斯酒店举行的第十届戈登研究会议，主题为“唾液腺和外分泌生物学”，题为“分泌器官的发育、稳态和修复：它们的微环境和控制它们的信号”。本次会议重点讨论了分泌器官的形成、维持、功能和修复。讲座将涵盖一系列模型系统，从无脊椎动物的分泌腺到高等动物的专业分泌器官，包括胰腺、肠道、肺部、泪腺、乳房和唾液腺。几个令人兴奋的会议将包括唾液腺和分泌器官发育的基本设计原则，分泌细胞生物学的最新进展，粘蛋白和其他分泌物质在上皮器官中的作用，调节分泌的机制和电路，分泌在宿主-微生物相互作用中的作用，分泌器官 疾病，最后是分泌器官再生和修复方面的最新进展。其中一次会议致力于成像、基因编辑和全基因组方法方面的最新技术进步，以了解分泌生物学。这次会议提供了一个独特的环境，来自世界各地从事唾液腺和其他外分泌器官研究的基础科学家和临床医生汇聚一堂。相对孤立的会议地点共享所有的食物，这将为经验丰富的研究和新研究之间、临床医生和基础科学家之间以及通过各种方法解决一系列生物学问题的个人之间发展关键联系提供充足的时间。唾液功能对我们处理食物、说话和保护口腔免受细菌和真菌感染的能力至关重要，细菌和真菌感染会导致龋齿和其他口腔健康问题。本次会议的目标是加快唾液腺和外分泌腺生物学的研究进展，最终目标是找到更好的治疗唾液腺和外分泌器官疾病的方法。为了实现这一目标，许多分泌器官生物学的专家被邀请在这次会议上进行口头陈述，并将鼓励所有与会者在下午的海报会议上展示最新发现。口头报告的时间表还将包括从海报摘要中挑选出的较短的演讲。这将确保在会议上展示最近令人兴奋的发现，并确保许多年轻人将发言。总体而言，这次会议的目标与NIDCR的使命很好地契合，即“通过研究、研究培训和传播健康信息来改善口腔、牙齿和颅面健康”。特别是，这次会议将促进从最近的分泌器官生物学研究中获得的知识的分享，以最终指导口腔健康政策和疾病治疗。