SmarToyGym: Smart detection of atypical toy-oriented actions in at-risk infants

SmarToyGym：智能检测高危婴儿的非典型玩具导向行为

• 批准号: 9127310
• 负责人: MICHELLE J. JOHNSON
• 金额: $ 20.1万
• 依托单位: UNIVERSITY OF PENNSYLVANIA
• 依托单位国家: 美国
• 财政年份: 2015
• 资助国家: 美国
• 起止时间: 2015-08-14 至 2018-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9127310
• 关键词: 3 year old; Achievement; Age; Behavior; Body measure procedure; Child; Childhood; Clinical; Complex; Data; Detection; Development; Early Diagnosis; Early Intervention; Early treatment; Effectiveness; Effectiveness of Interventions; Environment; Evaluation; Future; Goals; Hand; Health; Home environment; Impaired cognition; Impairment; Infant; Infant Development; Intervention; Lead; Leg; Life; Literature; Longevity; Measurement; Measures; Methodology; Monitor; Motion; Motor; Movement; Outcome; Physicians; Play; Posture; Predictive Value; Primary Health Care; Recruitment Activity; Reporting; Reproducibility; Research; Risk; Survival Rate; System; Testing; Time; Toy; Treatment outcome; Weight; Wireless Technology; Work; arm; cost; design; disability; functional disability; functional outcomes; grasp; high risk; high risk infant; improved; inclusion criteria; infant monitoring; insight; kinematics; motor impairment; non-invasive monitor; novel; predictive tools; pressure; response; screening; sensor; tool

 DESCRIPTION (provided by applicant): Increased survival rates of medically fragile infants lead to an increased number of children with functional impairments later in life. There is a critical need for clinical tools that can provide non- invasive monitoring of these at-risk infantsin their natural settings and early detection of motor delays and impairments. Early detection of delay or impairment provides the opportunity for early treatment which improves health outcomes for them over the lifespan. Motor development can be evaluated by studying infant play behavior and interactions with toys. As such, our long-term goal is to develop an advanced play environment, SmarToyGym, through which we can objectively assess the motor development of at-risk infants and quantify the effects of future interventions. Our working hypothesis is that metrics derived from measuring body and arm/hand movements while infants play within this environment will identify infants with atypical motor behavior. Our first specific aim is to develop a SmarToyGym where sensorized, wireless toys are strategically hung and placed within reach of infants to elicit toy-oriented body and arm/hand movements. Each toy will be equipped with sensors capable of measuring the infant's grasping actions such as squeezing, pinching, and shaking/tilting. A low-cost 3D motion capture system will be used to collect video data and the infants' reaching and body kinematics in response to the toys. A pressure mat will be used to measure postural changes to detect weight shifts, rolling, crawling and other movements away from the initial posture. Our second specific aim is to conduct proof-of-concept testing of the SmarToyGym with atypical and typical developing infants. We will include 24 infants ages 3 to 11 months who are categorized as high-risk or low-risk using the Bayley Infant Neurodevelopmental Screener (BINS) discriminative tool. Inclusion criteria for atypical infants will be motor impairment and/or cognitive impairment as defined by sub-scores on Bayley Scale of Infant Development (BSID-III) evaluation tool. Twelve atypical and 12 typical infants will be observed playing within SmarToyGym with and without toys for 5 consecutive days. Using this study, we will 1) identify a battery of metrics that are able to discriminate between atypical and typical infants, 2) determine the reliability/reproducibility of the measurements, and 3) determine the best clustering of the most sensitive metrics into an easy to use home screening methodology. Results from this R21 will inform the design of a larger trial to refine the tool and explore the potential for expanding the tool for treatment applications. The potential impact of our work is world-wide and can alter the lives of thousands of children through earlier intervention and better long-term functional outcomes.

 描述（由申请人提供）：医学上脆弱的婴儿存活率增加，导致日后出现功能障碍的儿童数量增加。迫切需要能够在这些高危婴儿的自然环境中对他们进行非侵入性监测并早期检测运动延迟和损伤的临床工具。早期发现延迟或损伤提供了早期治疗的机会，从而改善了他们一生的健康结果。运动发育可以通过研究婴儿的游戏行为和与玩具的互动来评估。因此，我们的长期目标是开发一个先进的游戏环境，SmarToyGym，通过它，我们可以客观地评估高危婴儿的运动发育，并量化未来干预的效果。我们的工作假设是，来自测量身体和手臂/手的运动，而婴儿在这种环境中玩的指标将识别婴儿与非典型的运动行为。我们的第一个具体 我们的目标是开发一个SmarToyGym，其中传感器，无线玩具被战略性地悬挂并放置在婴儿可触及的范围内，以引发玩具导向的身体和手臂/手运动。每个玩具将配备传感器，能够测量婴儿的抓握动作，如挤压，捏，摇晃/倾斜。一个低成本的3D动作捕捉系统将被用来收集视频数据和婴儿的达到和身体运动学响应的玩具。压力垫将用于测量姿势变化，以检测体重变化、滚动、爬行和其他偏离初始姿势的运动。我们的第二个具体目标是对SmarToyGym在非典型和典型发育中的婴儿中进行概念验证测试。我们将纳入24名3至11个月大的婴儿，他们使用Bayley Infant Neurodevelopmental Screener（BINS）区分工具被归类为高风险或低风险。非典型婴儿的入选标准将是运动障碍和/或认知障碍，如贝利婴儿发育量表（BSID-III）评估工具的分项评分所定义。将观察12名非典型和12名典型婴儿连续5天在SmarToyGym内玩玩具和不玩玩具。使用本研究，我们将1）确定一组能够区分非典型和典型婴儿的指标，2）确定测量的可靠性/再现性，3）确定最敏感指标的最佳聚类，以便于使用家庭筛查方法。R21的结果将为更大规模的试验设计提供信息，以完善该工具并探索扩展该工具用于治疗应用的潜力。的 我们工作的潜在影响是世界性的，可以通过早期干预和更好的长期功能结果改变成千上万儿童的生活。

项目成果

Ailu: An Affordable Sensorized Toy for Detection of Neuro and Motor Delays in Infants.

• DOI: 10.1109/icorr.2019.8779523
• 发表时间: 2019-06
• 期刊: IEEE ... International Conference on Rehabilitation Robotics : [proceedings]
• 作者: Ho ES;Torres W;Prosser L;Johnson MJ
• 通讯作者: Johnson MJ

Design of pediatric robot to simulate infant biomechanics for neuro-developmental assessment in a sensorized gym.

设计儿科机器人来模拟婴儿生物力学，以在传感健身房中进行神经发育评估。

• DOI: 10.1109/biorob52689.2022.9925371
• 发表时间: 2022
• 期刊: Proceedings of the ... IEEE/RAS-EMBS International Conference on Biomedical Robotics and Biomechatronics. IEEE/RAS-EMBS International Conference on Biomedical Robotics and Biomechatronics
• 作者: Panchal,Jal;Sowande,OFrancis;Prosser,Laura;Johnson,MichelleJ
• 通讯作者: Johnson,MichelleJ

Stereo 3D tracking of infants in natural play conditions.

• DOI: 10.1109/icorr.2017.8009353
• 发表时间: 2017-07
• 期刊: IEEE ... International Conference on Rehabilitation Robotics : [proceedings]
• 作者: Shivakumar SS;Loeb H;Bogen DK;Shofer F;Bryant P;Prosser L;Johnson MJ
• 通讯作者: Johnson MJ

Infants at risk for physical disability may be identified by measures of postural control in supine.

• DOI: 10.1038/s41390-021-01617-0
• 发表时间: 2022-04
• 期刊: Pediatric research
• 影响因子: 3.6
• 作者: Prosser LA;Aguirre MO;Zhao S;Bogen DK;Pierce SR;Nilan KA;Zhang H;Shofer FS;Johnson MJ
• 通讯作者: Johnson MJ

Towards Automated Emotion Classification of Atypically and Typically Developing Infants.

• DOI: 10.1109/biorob49111.2020.9224271
• 发表时间: 2020-11
• 期刊: Proceedings of the ... IEEE/RAS-EMBS International Conference on Biomedical Robotics and Biomechatronics. IEEE/RAS-EMBS International Conference on Biomedical Robotics and Biomechatronics
• 作者: Lysenko S;Seethapathi N;Prosser L;Kording K;Johnson MJ
• 通讯作者: Johnson MJ