Scientific Information Management and Literature-Based Evaluations for the National Toxicology Program (NTP) – Support for the DNTP Office of Nomination and Selection

一项涉及止痛药的发育/生殖影响的项目正在进行中，以支持DNTP提名和选择办公室（ONS）；DNTP正在开发其他项目。国家统计局负责监督化学品、其他候选物质的正式提名、审查和选择过程，以及国家毒物控制计划要研究或审查的问题。为了支持这一进程，国家统计局管理研究或审查提名的背景审查和概念文件的发展，以促进项目发展，公众沟通，演示和国家NTP科学顾问委员会的审查。这些项目涉及科学和技术专门知识以及承包商的支持，以便汇编、审查和分析来自科学文献和其他来源的关于环境物质的影响和可能影响公众健康的其他问题的信息和数据。

A project involving developmental/reproductive effects of analgesics to support the DNTP Office of Nomination and Selection (ONS) is in progress; additional projects are under development by DNTP. The ONS oversees a formal nomination, review, and selection process for chemicals, other candidate substances, and issues to be studied or reviewed by the NTP. To support this process, the ONS manages the development of background review and concept documents on nominations for research or review to facilitate project development, public communication, presentation, and review by the NTP Board of Scientific Counselors. These projects involve scientific and technical expertise and support from the contractor to compile, review, and analyze information and data from the scientific literature and other sources regarding the effects of environmental substances and other issues that may impact public health. Keywords: Systematic review, toxicology, epidemiology, exposure, cancer, non-cancer effects