Video Information Provider for HIV-Associated Non-AIDS (VIP-HANA) Symptoms

HIV 相关非艾滋病 (VIP-HANA) 症状视频信息提供者

• 批准号: 9269103
• 负责人: Rebecca Schnall
• 金额: $ 47.42万
• 依托单位: COLUMBIA UNIVERSITY HEALTH SCIENCES
• 依托单位国家: 美国
• 财政年份: 2015
• 资助国家: 美国
• 起止时间: 2015-07-16 至 2020-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9269103
• 关键词: 20 year old; AIDS related cancer; AIDS/HIV problem; Activities of Daily Living; Acute; Address; Adherence; Affect; Age; Area; Asthma; Cardiovascular Diseases; Cessation of life; Chronic Disease; Chronic Obstructive Airway Disease; Collaborations; Development; Diabetes Mellitus; Disease; Emotional; Enabling Factors; Epidemic; Evaluation; Face; Focus Groups; Frequencies; Gender; Goals; HIV; HIV Seropositivity; Health; Health Care Visit; Individual; Intervention; Knowledge; Learning; Liver diseases; Manuals; Measures; Modeling; Morbidity - disease rate; Online Systems; Osteoporosis; Outcome; Outcome Measure; Paper; Participant; Patient-Focused Outcomes; Perception; Persons; Phenotype; Pilot Projects; Population; Predisposing Factor; Provider; Quality of life; Recruitment Activity; Reinforcing Factor; Reporting; Research; Self Care; Self Management; Severities; Surveys; Symptoms; System; Testing; Work; antiretroviral therapy; arm; associated symptom; base; comparative efficacy; disability; experience; frailty; immune health; improved; innovation; medication compliance; multiple chronic conditions; primary outcome; public health relevance; reduce symptoms; resilience; social networking website; symptom management; symptom self management; symptomatic improvement; therapy adherence; uptake; usability; web app

 DESCRIPTION (provided by applicant): Video Information Provider for HIV-Associated Non-AIDS (VIP-HANA) Symptoms AIDS-related malignancies and death were hallmark features of the HIV epidemic until the mid-1990s. Today, a 20-year-old HIV-positive non-injection drug user in the US can expect to live to age 65. As a result, people living with HIV/AIDS (PLWHA) face new challenges from HIV-Associated Non-AIDS (HANA) conditions such as cardiovascular disease, osteoporosis, COPD, and diabetes. Since treatment does not fully restore immune health and multi-morbidity is high, PLWHA, especially those with HANA conditions, often experience re- occurring symptoms from both the disease and its treatment, making long-term management of symptoms critical for improved health outcomes. An individual's ability to self-manage the symptoms of his or her HIV illness has been shown to decrease symptom severity, improve quality of life, reduce disability, increase medication adherence, and promote health. The proposed research expands upon our innovative pilot work that developed and tested a web-based symptom reporting and self-management system, Video Information Provider (VIP) for PLWHA. The goal of the work in this proposed study is to develop and test an intervention, the VIP-HANA system, a web application that delivers self-care strategies tailored to symptom reporting, HANA condition(s) and gender. To address the needs of the growing population of PLWHA with HANA conditions, the aims of our study are to: (1a) Identify the most prevalent symptoms and self-care strategies of PLWHA with HANA conditions in order to modify the VIP system into the VIP-HANA system; (1b) Evaluate the VIP-HANA system for violations of usability principles; (2) Compare the efficacy of VIP-HANA to a control arm for ameliorating symptom frequency and intensity and secondary health outcomes in 100 PLWHA with HANA conditions over 6 months; and (3) Understand PLWHA's perceptions of the predisposing, enabling, and reinforcing factors for VIP-HANA use with theoretically-guided focus group sessions. Our study activities are focused on identifying the symptom experience and self-care strategies for PLWHA with HANA conditions and enhancing an existing web application for HIV symptom self-management. The proposed project focuses on the development and evaluation of VIP-HANA, an intervention aimed at improving symptom status, enhancing quality of life, increasing functional capacity, and reducing frailty in PLWHA. The proposed study is consistent with FOA: PA 13-210 "development, adaptation, or testing interventions aimed at identifying and managing symptoms related to HIV-Associated Non-AIDS (HANA) conditions, specifically functional capacity and frailty and increasing self-care of HIV-infected persons with HANA conditions." Findings from this study will increase knowledge of HANA symptoms, self-care strategies used to manage these symptoms, and the usability and efficacy of the VIP-HANA system.

 描述（由申请人提供）：艾滋病毒相关非艾滋病（VIP-HANA）症状的视频信息提供者艾滋病相关的恶性肿瘤和死亡是艾滋病毒流行的标志性特征，直到20世纪90年代中期。今天，在美国，一个20岁的艾滋病毒阳性非注射毒品使用者可以预期活到65岁。因此，艾滋病毒/艾滋病（PLWHA）感染者面临着来自艾滋病毒相关非艾滋病（HANA）疾病的新挑战，如心血管疾病，骨质疏松症，COPD和糖尿病。由于治疗不能完全恢复免疫健康，多重发病率很高，艾滋病毒/艾滋病感染者，特别是那些患有艾滋病毒/艾滋病的人，往往会因疾病及其治疗而反复出现症状，因此长期管理症状对改善健康结果至关重要。一个人的自我管理他或她的艾滋病毒疾病的症状的能力已被证明可以降低症状的严重程度，提高生活质量，减少残疾，增加药物依从性，并促进健康。拟议的研究扩大了我们的创新试点工作，开发和测试了基于网络的症状报告和自我管理系统，视频信息提供者（VIP）的PLWHA。这项拟议研究的目标是开发和测试一种干预措施，即VIP-HANA系统，这是一种网络应用程序，可提供针对症状报告、HANA状况和性别的自我护理策略。为了满足日益增长的艾滋病毒/艾滋病感染者（PLWHA）的需求，我们的研究目的是：（1a）确定艾滋病毒/艾滋病感染者（PLWHA）最常见的症状和自我护理策略，以便将VIP系统修改为VIP-HANA系统;（1b）评估VIP-HANA系统是否违反可用性原则;（2）比较VIP-HANA与对照组在改善100例患有HANA病症的PLWHA的症状频率和强度以及次级健康结果方面的疗效;（3）通过理论指导的焦点小组会议，了解PLWHA对VIP-HANA使用的诱发因素、使能因素和强化因素的看法。我们的研究活动的重点是确定症状的经验和自我保健策略的艾滋病毒感染者与HANA条件，并加强现有的网络应用程序的艾滋病毒症状自我管理。拟议项目的重点是制定和评估VIP-HANA，这是一项旨在改善症状状况、提高生活质量、增强功能能力和减少艾滋病毒/艾滋病感染者脆弱性的干预措施。拟议的研究符合FOA：PA 13-210“开发、调整或测试干预措施，旨在识别和管理与HIV相关的非艾滋病（HANA）病症相关的症状，特别是功能能力和虚弱，并增加患有HANA病症的HIV感染者的自我护理。“这项研究的结果将增加对HANA症状的了解，用于管理这些症状的自我护理策略，以及VIP-HANA系统的可用性和有效性。