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Mentoring and Research in Self-Management for Health Promotion and Disease Prevention

健康促进和疾病预防自我管理的指导和研究

基本信息

批准号：
10380063
负责人：
Rebecca Schnall
金额：
$ 4.29万
依托单位：
COLUMBIA UNIVERSITY HEALTH SCIENCES
依托单位国家：
美国
项目类别：
财政年份：
2019
资助国家：
美国
起止时间：
2019-04-17 至 2022-08-15
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/10380063
关键词：
AIDS prevention AIDS/HIV problem Address Affect Age Area Award Behavioral Biological Biological Markers Bisexual Chronic Disease Chronic stress Collection Common Data Element Competence Data Collection Development Development Plans Discipline of Nursing Disease Epidemiology Etiology Evaluation Exercise Fatigue Frequencies Funding Gays Goals Grant HIV HIV prevention trial Hair Health Health Promotion Hormonal Human immunodeficiency virus test Hydrocortisone Hypothalamic structure Individual Inflammatory Informatics International Intervention Knowledge Laboratories Learning Measures Medical Mentors Mid-Career Clinical Scientist Award (K24)Minority Groups Modeling Molecular Genetics Monitor National Institute of Nursing Research Nature Needs Assessment Nurses Outcome Pain Pathway interactions Patient Outcomes Assessments Patient Self-Report Patients Persons Pharmaceutical Preparations Phase Pilot Projects Pituitary Gland Population Populations at Risk Principal Investigator Process Quality of life Randomized Clinical Trials Randomized Controlled Trials Regimen Reporting Research Research Personnel Risk Sample Size Sampling Science Scientist Self Management Stress Symptoms Syphilis Syphilis Serodiagnosis Testing Time Training Training Activity Training Programs Treatment Efficacy Viral Load result Work Writing Youth base behavioral health biobehavior career comorbidity cytokine design disorder prevention experience health disparity high risk improved innovation insight interdisciplinary collaboration international center knowledge base leadership development men mobile application mobile computing next generation patient oriented patient oriented research patient population peer point of care testing potential biomarker prevent programs research data dissemination response self testing skills skills training study population symptom management symptom science symptom self management tool young man

项目摘要

Project Summary This K24 application is from a mid-career patient-oriented researcher with a research program focused on understanding the information needs of vulnerable patient populations and developing informatics-based self- management tools to promote health and prevent disease. This K24 application will build on my current portfolio of successful HIV research and enable me to focus on long-term objectives to broaden the scope of my research in the next phase of my career and to provide the protected time to mentor the next generation of nurse scientists in patient-oriented research (POR). Career Objectives: 1) Become a national and international leader in combining bio-behavioral and informatics approaches for the management of chronic illness, largely focusing on HIV-related illnesses, as a model for other underserved chronic illness populations; 2) Gain expertise in molecular genetics in symptom science to advance my program of research on informatics strategies to improve bio-behavioral health outcomes; 3) Transform my laboratory into a local, regional, national, and international center of excellence for precision nursing, bio-behavioral health interventions, and self-management of chronic illness; and 4) Implement an outstanding training program in POR in self- management and informatics for the next generation of nurse scientists. Mentoring Plan: Using an individualized training approach, which includes a needs assessment of core research competencies and an ongoing intensive evaluation process, each mentee will monitor their progress through an Individual Development Plan (IDP). They will also participate in several training modules tailored to their individual needs, e.g., Didactics; Focused Skills Training; Applied, Hands-on Training & Team Management; Research Dissemination; and Grant Writing and Study Development. The Research Strategy of this proposal focuses on incorporating biomarkers into my existing studies to augment the pace and scope of two HIV self- management trials and two HIV prevention trials. My mentees and I will work to achieve the following specific aims. Aim 1: Determine the extent that inflammatory cytokines, which may serve as biomarkers, are related to symptom burden in persons living with HIV. Aim 2: Explore changes in cortisol concentrations in hair as a hormonal response to changes in chronic stress over time in youth who are at high-risk for HIV. Aim 3: Conduct a pilot study to assess the feasibility of the “mLab App Plus” which incorporates the use of the duplex HIV/syphilis point-of-care test. This research trajectory holds promise for enhancing behavioral health research by clarifying the influence of biomarkers as predictors of efficacy in our extant trials. Moreover, since HIV/AIDS research has recently been shown to yield dividends across medical fields, the proposed work with persons living with and at risk for HIV can easily be extended to other chronic illnesses, thus informing a wide array of learning opportunities for mentees. Through these aims, I will provide my mentees with practical experience in proposing, designing, and conducting POR in areas of self-management research that match their career goals.

项目总结