Training in Cardiovascular Imaging Research

心血管影像研究培训

• 批准号: 9278162
• 负责人: CHRISTOPHER M. KRAMER
• 金额: $ 9.1万
• 依托单位: UNIVERSITY OF VIRGINIA
• 依托单位国家: 美国
• 财政年份: 2004
• 资助国家: 美国
• 起止时间: 2004-07-01 至 2021-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9278162
• 关键词: Research; Training; cardiovascular imaging

 DESCRIPTION (provided by applicant): Cardiovascular disease is the major cause of morbidity and mortality in the United States. In fact, nearly 1 in 3 deaths in 2011 was due to cardiovascular disease (CVD), most of those due to coronary heart disease and 34% of the deaths occur before age 75. The need for improved noninvasive methods to detect early disease and to help manage patients with chronic disease has therefore never been as critical. Technical advances in noninvasive cardiovascular imaging have resulted in increasing use over recent years. Nuclear cardiology and echocardiography are mature technologies that are commonly used in clinical practice. Cardiovascular magnetic resonance imaging (CMR), computed tomographic angiography (CTA), and positron emission tomography (PET) are playing a growing role in the clinical assessment of CVD and are relatively new to cardiovascular training programs. The number of physicians who have in-depth expertise in the physics, engineering, and molecular applications in all 5 major cardiovascular imaging modalities remains limited. The University of Virginia (UVA) is one of a handful of centers in the U.S. that have high-level clinical, physics, engineering, and molecular expertise in all cardiovascular imaging modalities, as well as a track record of training physicians in research. Over the past decade, trainees have been highly productive in terms of publication and the majority have gone on to academic careers in outstanding institutions around the U.S. Two former trainees joined the UVA faculty and both are funded by K23 awards. The purpose of this grant renewal proposal is to continue and further develop the training program that provides comprehensive training in cardiovascular imaging research. The program provides trainees with outstanding opportunities to interact closely with imaging physicists and engineers who together offer the promise of improvements in both the clinical applications of these newer technologies and further development of and applications of translational imaging. Trainees have dual mentorship from a PhD imaging scientist and a MD clinician investigator. The goal of the training is to develop the next generation of academic investigators in cardiovascular imaging who can interact across disciplines. Trainees undergo a rigorous 2-year research training program following a 2-year clinical cardiovascular training program completed at the UVA or a 3-year program completed at another institution. Two fellows per year enter the program such that there are up to 4 fellows enrolled at any one time. A complete didactic program is offered including instruction in imaging physics and engineering, biostatistics, epidemiology, clinical research methodology, and medical ethics. Fellows receive training in clinical CMR, CTA, and PET. Research training is comprehensive and combines clinical and basic cardiovascular imaging research for each trainee with any of the modalities.

 描述（由适用提供）：心血管疾病是美国发病率和死亡率的主要原因。实际上，2011年的三分之一死亡归因于心血管疾病（CVD），大多数是由于冠心病引起的，而34％的死亡发生在75岁之前。需要改善非侵袭性方法以检测早期疾病并帮助治疗慢性病患者的早期疾病至关重要。近年来，无创心血管成像的技术进步导致使用越来越多。核心脏病学和超声心动图是临床实践中通常使用的成熟技术。心血管磁共振成像（CMR），计算机断层造影术（CTA）和正电子发射断层扫描（PET）在CVD的临床评估中起着越来越多的作用，并且对心血管训练计划的新手相对较新。在所有5种主要的心血管成像方式中具有深入的专业知识的医生数量仍然有限。弗吉尼亚大学（UVA）是美国少数几个中心之一，在所有心血管成像方式中都具有高级临床，物理，工程和分子专业知识，并且是研究培训医生的记录。在过去的十年中，学员在出版方面的生产力很高，大多数人都从美国各地的杰出机构的学术职业开始，两位前学员加入了UVA教职员工，两者都获得了K23奖。该赠款更新建议的目的是继续并进一步制定培训计划，该计划在心血管成像研究中提供全面的培训。该计划为受训者提供了与成像物理学家和工程师紧密互动的绝佳机会，他们共同提供了改进这些新技术的临床应用以及转化成像的进一步开发和应用的希望。受训者具有博士成像科学家和MD临床研究者的双重心态。培训的目的是发展可以跨学科互动的心血管成像中的下一代学术研究人员。在UVA完成了为期2年的临床心血管培训计划或在另一家机构完成的3年计划之后，受训人员接受了一项严格的2年研究培训计划。每年有两个研究员进入该计划，以至于任何一次都有多达4名研究员。提供了一个完整的教学计划，包括有关成像物理和工程，生物统计学，流行病学，临床研究方法论和医学伦理学的说明。研究员接受临床CMR，CTA和PET的培训。研究培训是全面的，将每个学员的临床和基本心血管成像研究与任何模式结合在一起。