Training in Cardiovascular Imaging Research

心血管影像研究培训

• 批准号: 9278162
• 负责人: CHRISTOPHER M. KRAMER
• 金额: $ 9.1万
• 依托单位: UNIVERSITY OF VIRGINIA
• 依托单位国家: 美国
• 财政年份: 2004
• 资助国家: 美国
• 起止时间: 2004-07-01 至 2021-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9278162
• 关键词: Research; Training; cardiovascular imaging

 DESCRIPTION (provided by applicant): Cardiovascular disease is the major cause of morbidity and mortality in the United States. In fact, nearly 1 in 3 deaths in 2011 was due to cardiovascular disease (CVD), most of those due to coronary heart disease and 34% of the deaths occur before age 75. The need for improved noninvasive methods to detect early disease and to help manage patients with chronic disease has therefore never been as critical. Technical advances in noninvasive cardiovascular imaging have resulted in increasing use over recent years. Nuclear cardiology and echocardiography are mature technologies that are commonly used in clinical practice. Cardiovascular magnetic resonance imaging (CMR), computed tomographic angiography (CTA), and positron emission tomography (PET) are playing a growing role in the clinical assessment of CVD and are relatively new to cardiovascular training programs. The number of physicians who have in-depth expertise in the physics, engineering, and molecular applications in all 5 major cardiovascular imaging modalities remains limited. The University of Virginia (UVA) is one of a handful of centers in the U.S. that have high-level clinical, physics, engineering, and molecular expertise in all cardiovascular imaging modalities, as well as a track record of training physicians in research. Over the past decade, trainees have been highly productive in terms of publication and the majority have gone on to academic careers in outstanding institutions around the U.S. Two former trainees joined the UVA faculty and both are funded by K23 awards. The purpose of this grant renewal proposal is to continue and further develop the training program that provides comprehensive training in cardiovascular imaging research. The program provides trainees with outstanding opportunities to interact closely with imaging physicists and engineers who together offer the promise of improvements in both the clinical applications of these newer technologies and further development of and applications of translational imaging. Trainees have dual mentorship from a PhD imaging scientist and a MD clinician investigator. The goal of the training is to develop the next generation of academic investigators in cardiovascular imaging who can interact across disciplines. Trainees undergo a rigorous 2-year research training program following a 2-year clinical cardiovascular training program completed at the UVA or a 3-year program completed at another institution. Two fellows per year enter the program such that there are up to 4 fellows enrolled at any one time. A complete didactic program is offered including instruction in imaging physics and engineering, biostatistics, epidemiology, clinical research methodology, and medical ethics. Fellows receive training in clinical CMR, CTA, and PET. Research training is comprehensive and combines clinical and basic cardiovascular imaging research for each trainee with any of the modalities.

 描述（由申请人提供）：心血管疾病是美国发病率和死亡率的主要原因。事实上，2011年近三分之一的死亡是由于心血管疾病（CVD），其中大多数是由于冠心病，34%的死亡发生在75岁之前。因此，需要改进的非侵入性方法来检测早期疾病并帮助管理慢性病患者，这一点从未如此重要。近年来，无创心血管成像的技术进步导致了越来越多的使用。核心脏病学和超声心动图是临床实践中常用的成熟技术。心血管磁共振成像（CMR）、计算机断层扫描血管造影（CTA）和正电子发射断层扫描（PET）在心血管疾病的临床评估中发挥着越来越重要的作用，并且对于心血管训练计划来说是相对较新的。在所有5种主要心血管成像模式中具有物理学、工程学和分子应用方面深入专业知识的医生数量仍然有限。弗吉尼亚大学（UVA）是美国少数几个在所有心血管成像模式方面拥有高水平临床，物理，工程和分子专业知识的中心之一，以及在研究中培训医生的跟踪记录。在过去的十年中，学员在出版方面的工作效率很高，大多数人都在美国各地的优秀机构从事学术事业。这项资助更新提案的目的是继续并进一步发展提供心血管成像研究综合培训的培训计划。该计划为学员提供了与成像物理学家和工程师密切互动的绝佳机会，这些物理学家和工程师共同承诺改善这些新技术的临床应用以及平移成像的进一步发展和应用。学员有来自博士成像科学家和医学博士临床研究员的双重导师。培训的目标是培养下一代心血管成像领域的学术研究人员，他们可以跨学科进行互动。受训人员在UVA完成2年临床心血管培训计划或在另一家机构完成3年计划后，接受严格的2年研究培训计划。每年有两名研究员进入该计划，因此任何时候最多有4名研究员入学。一个完整的教学计划，包括成像物理和工程，生物统计学，流行病学，临床研究方法和医学伦理学的教学。研究员接受临床CMR，CTA和PET的培训。研究培训是全面的，并结合临床和基础心血管成像研究，为每个学员与任何形式。