Noninvasive Cardiovascular Imaging Research Training Program

描述（由申请人提供）：CV疾病的诊断和管理依赖于非侵入性检测，以加强高风险患者的识别并优化管理策略。分子影像学是改善风险评估的关键工具，并导致更个性化的诊断和治疗疾病的方法。我们的目标是培养具有临床和调查技能的CV成像专家，以建立独立的职业生涯，指导他人，并领导自己的CV成像计划。我们在多模态CV成像研究中设计了一个全面的基于课程的培训计划，其中包括：（1）由MD和/或PhD科学家的多学科教师讲授的为期2年的转化研究培训计划;（2）由定向讲座组成的扩展教学临床和基础科学研究课程;基础分析和生物伦理学课程，高级课程工作（包括两个针对具体方案的高级课程）;以及持续的学习机会;和（3）指导临床或转化研究经验，包括研究方法的正式培训，以及研究项目的开发，包括方案开发，实验执行，关键数据分析，口头报告，手稿撰写，和赠款准备。我们寻求美国国立卫生研究院的支持，在成像科学的研究培训2研究员（MD或MD博士）每年。我们的计划是开放给心脏病学家，放射科医生和其他成像专家。我们聚集了12名优秀的教师导师，他们每个人都在心脏成像科学的前沿进行研究。总的来说，他们有超过50个活跃的校外赠款，并指导了170多个前/博士后研究员在基础和临床心脏成像研究的各个方面。在整个BWH，MGH和哈佛医学院社区的教师，学员和其他研究人员之间的广泛合作，进一步增加了该计划的科学影响。我们预计，我们的学员将实现我们的总体目标，我们的毕业生将传播CV成像培训，最终创造成像科学家的临界质量，以满足我们人口的医疗保健需求。相关性（参见说明）：严重缺乏受过训练的人员，他们具备知识和技能，能够弥合成像技术与支持使用这种技术的证据之间的差距。由于心血管成像对成本的影响，它已成为政策制定者的“热点”，因此拟议的培训计划特别有价值。

DESCRIPTION (provided by applicant): The diagnosis and management of CV disease relies on non-invasive testing to enhance the identification of high risk patients and optimize management strategies. Molecular imaging is a key tool to improve risk assessment and lead to more individualized approaches to diagnosing and treating disease. Our objective is to produce CV imaging specialists with the clinical and investigative skills to establish independent careers, mentor others, and lead their own CV Imaging programs. We designed a comprehensive curriculum-based training program in multi-modality CV Imaging research that includes: (1) a 2-year training program in translational research taught by a multidisciplinary faculty of MD and/or PhD scientists; (2) an extended didactic clinical and basic science research curriculum consisting of orientation lectures; basic analytic and bioethics courses, advanced course work (including two program-specific advanced courses); and ongoing learning opportunities; and (3) a mentored clinical or translational research experience that includes formal training in research methodology, and the development of a research project including protocol development, experimental execution, critical data analysis, oral presentation, manuscript writing, and grant preparation. We seek NIH support for research training in imaging science for 2 fellows (MD or MD PhD) annually. Our program is opened to cardiologists, radiologists and other imaging specialists. We have assembled a group of 12 outstanding faculty mentors, each of whom are pursuing research at the cutting-edge of cardiac imaging science. Collectively, they have over 50 active extramural grants and have mentored over 170 pre/post doctoral fellows in various aspects of basic and clinical cardiac imaging research. Extensive collaboration among the faculty, trainees, and other investigators throughout the BWH, MGH, and Harvard Medical School communities, further increase the Program's scientific impact. We anticipate that our trainees will fulfill our overall objectives and that our graduates will disseminate CV Imaging training, ultimately creating a critical mass of imaging scientists to meet the health care needs of our population. RELEVANCE (See instructions): There is a severe shortage of trained individuals with the knowledge and skills to bridge the gap between imaging technology and the evidence to support the use of such technology. The proposed training program is particularly valuable now that cardiovascular imaging has become the 'hot button' for policy makers because of its effect on costs.