Noninvasive Cardiovascular Imaging Research Training Program

描述(申请人提供)：心血管疾病的诊断和治疗依赖于非侵入性检测，以加强对高危患者的识别和优化管理策略。分子成像是改进风险评估和导致诊断和治疗疾病的更个性化方法的关键工具。我们的目标是培养具有临床和调查技能的心血管成像专家，以建立独立的职业生涯，指导其他人，并领导他们自己的心血管成像项目。我们设计了基于课程的多模式简历影像研究综合培训计划，其中包括：(1)由医学博士和/或博士科学家组成的多学科学院教授的为期两年的翻译研究培训计划；(2)由定向讲座组成的扩展教学临床和基础科学研究课程；基础分析和生物伦理学课程、高级课程作业(包括两个特定于项目的高级课程)；以及持续的学习机会；以及(3)有指导的临床或转化性研究经验，包括研究方法的正式培训，以及研究项目的开发，包括方案制定、实验执行、关键数据分析、口头陈述、手稿写作和拨款准备。我们寻求美国国立卫生研究院的支持，每年为2名研究员(医学博士或医学博士)提供成像科学研究培训。我们的计划向心脏病专家、放射科医生和其他影像专家开放。我们已经组建了一个由12名优秀的教师导师组成的小组，他们中的每一个人都在从事心脏成像科学的前沿研究。他们总共有50多项积极的校外资助，并在基础和临床心脏成像研究的各个方面指导了170多名博士后/博士后研究员。BWH、MGH和哈佛医学院社区的教职员工、实习生和其他研究人员之间的广泛合作，进一步增加了该计划的科学影响。我们预计，我们的实习生将实现我们的总体目标，我们的毕业生将传播简历成像培训，最终培养出一大批成像科学家，以满足我们人口的医疗保健需求。相关性(见说明)：严重缺乏训练有素的人员，他们拥有知识和技能，能够弥合成像技术与支持使用这种技术的证据之间的差距。由于心血管成像对成本的影响，拟议中的培训计划尤其有价值，因为它已经成为政策制定者的“热点”。

DESCRIPTION (provided by applicant): The diagnosis and management of CV disease relies on non-invasive testing to enhance the identification of high risk patients and optimize management strategies. Molecular imaging is a key tool to improve risk assessment and lead to more individualized approaches to diagnosing and treating disease. Our objective is to produce CV imaging specialists with the clinical and investigative skills to establish independent careers, mentor others, and lead their own CV Imaging programs. We designed a comprehensive curriculum-based training program in multi-modality CV Imaging research that includes: (1) a 2-year training program in translational research taught by a multidisciplinary faculty of MD and/or PhD scientists; (2) an extended didactic clinical and basic science research curriculum consisting of orientation lectures; basic analytic and bioethics courses, advanced course work (including two program-specific advanced courses); and ongoing learning opportunities; and (3) a mentored clinical or translational research experience that includes formal training in research methodology, and the development of a research project including protocol development, experimental execution, critical data analysis, oral presentation, manuscript writing, and grant preparation. We seek NIH support for research training in imaging science for 2 fellows (MD or MD PhD) annually. Our program is opened to cardiologists, radiologists and other imaging specialists. We have assembled a group of 12 outstanding faculty mentors, each of whom are pursuing research at the cutting-edge of cardiac imaging science. Collectively, they have over 50 active extramural grants and have mentored over 170 pre/post doctoral fellows in various aspects of basic and clinical cardiac imaging research. Extensive collaboration among the faculty, trainees, and other investigators throughout the BWH, MGH, and Harvard Medical School communities, further increase the Program's scientific impact. We anticipate that our trainees will fulfill our overall objectives and that our graduates will disseminate CV Imaging training, ultimately creating a critical mass of imaging scientists to meet the health care needs of our population. RELEVANCE (See instructions): There is a severe shortage of trained individuals with the knowledge and skills to bridge the gap between imaging technology and the evidence to support the use of such technology. The proposed training program is particularly valuable now that cardiovascular imaging has become the 'hot button' for policy makers because of its effect on costs.