Noninvasive Cardiovascular Imaging Research Training Program

无创心血管影像研究培训计划

• 批准号: 9301342
• 负责人: Marcelo F DI CARLI
• 金额: $ 49.14万
• 依托单位: BRIGHAM AND WOMEN'S HOSPITAL
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-07-01 至 2020-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9301342
• 关键词: Research Training; Training Programs; cardiovascular imaging

 DESCRIPTION (provided by applicant): Cardiovascular (CV) disease is the leading cause of morbidity and mortality in the US and worldwide. Non-invasive imaging provides valuable information to assess differential diagnosis and to help formulate a management plan. Unfortunately, most existing training programs in CV imaging offer only fragmented and discipline-constrained training opportunities, and very few offer training that incorporates clinicl and translational research in imaging science. This is the first competing renewal application for Brigham and Women's Hospital noninvasive cardiovascular imaging T32 program. This program offers post-doctoral research training for individuals with an MD, or combined MD/PhD degrees, who have completed clinical training in cardiology, radiology, or cardiovascular imaging who are committed to pursuing an academic career in CV imaging science. Our objective is to provide a multidisciplinary research environment that integrates CV biology, pharmacology, and imaging technology, with which to train clinician-scientists in translational imaging science. All the fellws have presented their work at national meetings. In the first 3.5 years of this T32 grant, our trainees have authored 63 manuscripts (some currently under review) with more than 90% being original contributions. Importantly, those who completed training to date have obtained academic faculty positions and have already obtained or are actively pursuing independent funding opportunities, all strong indicators of program success. Our mentors are primarily comprised of cardiologists and radiologists, but also include faculty from Pulmonary Medicine, Pathology, Anesthesia, Endocrinology, and the Center for Systems Biology at MGH. All of the mentors have an extensive portfolio of collaborations. We offer research opportunities in seven primary areas of imaging research: (1) molecular imaging, (2) myocardial structure and function, (3) cell-based therapy, (4) genetics, (5) pulmonary hypertension, (6) vascular imaging, and (7) outcomes research. The proposed program supports 3 positions/year for two years of continued research training. With this renewal, we continue our primary goals of providing leadership in academic cardiovascular imaging and training future leaders in imaging science to improve outcomes in cardiovascular disease.

 描述(申请人提供)：心血管疾病是美国和世界范围内发病率和死亡率的主要原因。非侵入性成像提供了有价值的信息来评估鉴别诊断和帮助制定管理计划。不幸的是，大多数现有的心血管成像培训计划只提供零散和学科受限的培训机会，很少提供结合影像科学临床和转化性研究的培训。这是布里格姆和妇女医院非侵入性心血管成像T32计划的第一个竞争性续签申请。该计划为拥有医学博士学位或医学博士/博士学位的个人提供博士后研究培训，这些个人已完成心脏病学、放射学或心血管成像方面的临床培训，并致力于从事心血管成像科学的学术事业。我们的目标是提供一个整合心血管生物学、药理学和成像技术的多学科研究环境，用来培训临床医生和科学家翻译成像科学。所有的人都在全国会议上介绍了他们的工作。在T32助学金的头3.5年里，我们的学员已经撰写了63篇手稿(一些正在审查中)，其中90%以上是原创贡献。重要的是，那些到目前为止完成培训的人已经获得了学术教师的职位，并且已经获得或正在积极寻求独立的资助机会，这些都是项目成功的有力指标。我们的导师主要由心脏病专家和放射科医生组成，但也包括来自肺内科、病理学、麻醉学、内分泌学和麻省理工学院系统生物学中心的教员。所有的导师都有广泛的合作组合。我们提供影像研究的七个主要领域的研究机会：(1)分子成像、(2)心肌结构和功能、(3)基于细胞的治疗、(4)遗传学、(5)肺动脉高压、(6)血管成像和(7)结果研究。拟议的方案支持每年3个职位，为期两年的持续研究培训。通过这次更新，我们继续我们的主要目标，即在学术心血管成像领域提供领导地位，并培训成像科学的未来领导者，以改善心血管疾病的结果。