Michigan Center on Lifestage Environmental Exposures and Disease

密歇根生命阶段环境暴露和疾病中心

• 批准号: 9058297
• 负责人: Rita K Loch-Caruso
• 金额: $ 63.72万
• 依托单位: UNIVERSITY OF MICHIGAN AT ANN ARBOR
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-04-15 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/9058297
• 关键词: Address; Administrator; Advisory Committees; Beryllium; Budgets; Collaborations; Communication; Communities; Community Outreach; Consultations; Core Facility; Data; Disease; Educational workshop; Endocrine; Ensure; Environmental Exposure; Environmental Hazards; Environmental Health; Evaluation; Event; Faculty; Feedback; Focus Groups; Fostering; Funding Opportunities; Genetic; Goals; Grant; Individual; Inflammation; Internet; Knowledge; Leadership; Life; Medical; Mentors; Metabolic; Michigan; Mission; National Institute of Environmental Health Sciences; Oxidative Stress; Performance; Pilot Projects; Program Evaluation; Publications; Records; Reporting; Research; Research Infrastructure; Research Personnel; Research Training; Science; Scientist; Services; Staging; Structure; Technology; Translations; Vision; Visit; Work; career; career development; efficacy evaluation; epigenetic regulation; human disease; improved; innovation; meetings; member; programs; public health intervention; response; skills; symposium; theories; tool

SUMMARY/ABSTRACT (Administrative Core) The Michigan Center on Lifestage Environmental Exposures and Disease (M-LEEaD) mission has two overarching goals: to accelerate research that defines and explains impacts of environmental exposures during vulnerable stages of life, and to promote translation of these findings to improve medical and public health interventions for the mitigation of human disease. We implement our mission through integrated research, training and community engagement overseen by the Administrative Core. The Administrative Core is led by the center director with assistance from the deputy director. This core is the administrative unit for the Pilot Project Program (led by the deputy director), Career Development Program (led by an Associate Director), and Research Engagement Program (led by an Associate Director). Three Research Teams (Inflammation & Oxidative Stress Team; Endocrine & Metabolic Disruption; and Genetics & Epigenetics Regulation) are elements of the Research Engagement Program with research team leaders included as members of the Administrative Core. The research teams are key mechanisms for members to explore new collaborations and for coordinating responses to funding opportunities. Inclusion of leadership of the Pilot Project Program, Career Development Program, and Research Engagement Program in the Administrative Core addresses the center objective that these programs operate in an integrative manner. Administrative Core Faculty will be assisted by an administrative assistant and web designer/administrator. The core works as collaborative team to provide an effective and efficient administrative infrastructure to achieve the mission of M-LEEaD. The core is responsible for organizing M-LEEaD activities such as meetings, retreats, consultant visits, symposia, seminars, and focus groups, and maintaining records of reports, minutes, and evaluation results from such events. In addition, the core provides fiduciary oversight of the budgets. The core obtains and considers input on emerging theories, paradigms, technologies, and discoveries in environmental health sciences and biomedicine at multiple levels, from research team reports to director meetings to Internal Advisory Committee meetings and including the External Advisory Board. The Administrative Core has responsibility for the Career Development Program and the Pilot Project Program, ensuring that these programs encourage innovative research for all members, but especially for early-stage investigators. The core ensures inclusion of input on opportunities for community engagement and fosters multi-directional dialogue among M-LEEaD scientists, community members, and regulatory stakeholders. The core coordinates responses to urgent environmental hazards and concerns, including interactions with other NIEHS Environmental Health Sciences Core Centers, the NIEHS, and other relevant organizations. Finally, the core is responsible for evaluation of the efficacy of the center programs, cores, and activities, taking corrective action as warranted.

摘要/摘要（行政核心） 密歇根生命阶段环境暴露和疾病中心（M-LEEaD）的使命有两个 总体目标：加速界定和解释环境暴露影响的研究， 生命的脆弱阶段，并促进这些发现的转化，以改善医疗和公共卫生 为减轻人类疾病而采取的干预措施。我们通过综合研究来实现我们的使命， 培训和社区参与由行政核心监督。行政核心由 中心主任在副主任的协助下。该核心是试点的行政单位 项目计划（由副主任领导），职业发展计划（由副主任领导），以及 研究参与计划（由副主任领导）。三个研究团队（炎症和 氧化应激团队;内分泌和代谢干扰;以及遗传学和表观遗传学调节） 研究参与计划的要素，包括研究团队领导人作为成员， 行政核心。研究小组是成员探索新合作的关键机制， 协调对筹资机会的反应。包括试点项目计划的领导，职业生涯 发展计划和研究参与计划在行政核心地址的中心 目标是这些方案以综合方式运作。行政核心教师将协助 行政助理和网页设计师/管理员。核心团队作为协作团队， 有效和高效的行政基础设施，以实现M-LEEaD的使命。核心是 负责组织M-LEEaD活动，如会议，务虚会，顾问访问，研讨会， 研讨会和焦点小组，并保存报告，会议记录和评估结果， 事件此外，核心小组还对预算进行信托监督。核心获取并考虑输入 关于环境健康科学的新兴理论、范式、技术和发现， 从研究团队报告到董事会议，再到内部咨询委员会， 会议，包括外部咨询委员会。行政核心负责职业生涯 发展计划和试点项目计划，确保这些计划鼓励创新 研究为所有成员，但特别是为早期阶段的调查人员。核心确保纳入关于 社区参与的机会，并促进M-LEEaD科学家之间的多方向对话， 社区成员和监管利益相关者。核心协调对紧急环境 危害和问题，包括与其他NIEHS环境健康科学核心中心的互动， NIEHS和其他相关组织。最后，核心负责评估 中心计划、核心和活动，采取必要的纠正措施。