San Francisco Bay Clinical Trials Unit

描述（由申请人提供）：旧金山弗朗西斯科湾区经历了一场特别激烈的艾滋病毒流行病，男男性行为者（MSM），黑人和拉丁裔人口在该地区受到最严重的影响。Susan Buchbinder博士和Diane Havlir博士分别是艾滋病预防和治疗领域的科学领导者。他们将共同组成旧金山弗朗西斯科湾区临床试验单位（SFBay CTU），隶属于HVTN，HPTN，MTN和ACTG。这个综合研究组织将通过这些网络实现3个具体目标：1）通过科学领导推进预防和治疗科学及其交叉; 2）有效实施临床试验，并严格遵守方案， 让不同的社区参与; 3）培养新一代艾滋病毒预防和治疗科学的不同领导者。Buchbinder博士和Havlir博士加入了一个由才华横溢的研究人员组成的多元化人才库，他们在整个网络中提供领导，在许多科学领导委员会和工作组中任职，并主持一系列预防和治疗方案。3个临床研究中心（由Buchbinder领导的Bridge HIV、由Havlir领导的UCSF和由Zolopa领导的斯坦福大学）在招募、保留和遵守方案要求方面都有卓越的记录，并积极参与当地社区的研究。 相关性：新成立的弗朗西斯科湾临床试验单位将在旧金山弗朗西斯科、奥克兰、圣何塞及其周边社区进行艾滋病毒疫苗、预防和治疗试验。通过汇集领先的科学家和不同的社区在旧金山弗朗西斯科湾区，这个新的研究单位将开发方法，以预防和治疗艾滋病毒感染，并致力于一个有效的艾滋病毒疫苗和治疗。

DESCRIPTION (provided by applicant): The San Francisco Bay Area has experienced a particularly intense HIV epidemic, with men who have sex with men (MSM), Black, and Latino populations most heavily impacted in the region. Drs. Susan Buchbinder and Diane Havlir are scientific leaders in HIV prevention and treatment, respectively. Together they will form the San Francisco Bay Area Clinical Trials Unit (SFBay CTU), affiliated with the HVTN, HPTN, MTN, and ACTG. This integrated research organization will accomplish 3 specific aims through these Networks: 1) advance prevention and treatment science and their intersection through scientific leadership; 2) implement clinical trials efficiently and with excellent adherence to protocol while engaging diverse communities; and 3) develop a new generation of diverse leaders in HIV prevention and treatment science. Drs. Buchbinder and Havlir are joined by a diverse pool of talented investigators who have provided leadership across the Networks, serving on numerous scientific leadership committees and working groups and chairing a range of prevention and treatment protocols. The 3 Clinical Research Sites (Bridge HIV led by Buchbinder, UCSF led by Havlir, and Stanford led by Zolopa) all have a record of excellence in enrollment, retention, and adherence to protocol requirements, and actively engage local communities in their research. RELEVANCE: The newly formed San Francisco Bay Clinical Trials Unit will conduct HIV vaccine, prevention and treatment trials in San Francisco, Oakland, San Jose, and their surrounding communities. By bringing together leading scientists and a diverse community in the San Francisco Bay Area, this new research unit will develop ways to prevent and treat HIV infections and work towards an effective HIV vaccine and cure.