Microbiology and Immunology Training for HIV and HIV-Related Research in Uganda (MITHU)

 描述（由申请人提供）：这个新的培训计划，题为“微生物学和免疫学培训艾滋病毒和艾滋病毒相关的研究在乌干达”（MITHU）建立在凯斯西储大学（CWRU）的28年培训记录和合作伙伴在马凯雷雷大学（MU）和联合临床研究中心（JCRC）。MITHU的重点是基础微生物学和免疫学的生物医学培训，以应用于艾滋病毒和艾滋病毒/艾滋病相关疾病的研究。该计划旨在满足乌干达同事确定的最基本的培训需求，其长期目标是加强乌干达主要大学和医学院的生物医学研究能力。MITHU的具体目标是：1。通过支持在CWRU完成硕士水平培训的有才华的年轻乌干达科学家的微生物学和免疫学博士水平培训，加强乌干达在教师一级的生物医学研究能力。2.通过支持MU健康科学学院生物医学科学学院的硕士水平培训，加强乌干达生物医学科学的研究生教育。3.建立艾滋病毒及其并发症的区域专门知识，建立在基础设施和乌干达-CWRU研究合作（UCRC）正在进行的研究。4.通过乌干达卫生科学家协会（USHS）培养一种指导年轻和发展中的实验室科学家的文化。5.继续密切MITHU与JCRC和MU的实验室之间的合作，为乌干达的免疫学和微生物学研究提供先进的设施，用于培训和返回的受训人员。MITHU提出了一个全面的基础科学计划，强调培训，解决艾滋病毒流行病在乌干达造成的不断变化的情况。拟议的计划将平衡MU和CWRU之间的教育和培训经验，在乌干达进行硕士水平的培训，在美国进行博士培训。我们将在乌干达开设关于艾滋病毒和艾滋病毒/艾滋病相关感染的课程，重点是基础科学和技术的最新创新。本课程将作为硕士课程的核心课程，将由乌干达和CWRU的讲师团队授课，他们具有基础和临床病毒学，艾滋病毒的发病机制和耐药性，艾滋病毒/艾滋病并发症，特别是艾滋病毒/结核病，以及基础和临床免疫学的专业知识。随着乌干达青年生物医学科学家队伍的壮大，将需要乌干达导师。MITHU将与USHS组织导师培训，USHS是一个由前乌干达CWRU学员组织的社团。MITHU的研究培训将建立在由NIH，CDC，B&MGF，EDTCP等资助的UCRC项目的基础设施和研究活动上。他们为MU的硕士培训创造了一个强大的环境，并为CWRU的博士培训产生了生物医学假设。

 DESCRIPTION (provided by applicant): This new training program, entitled "Microbiology and Immunology Training for HIV and HIV-Related Research in Uganda" (MITHU) builds on the 28 year training record of Case Western Reserve University (CWRU) and partners at Makerere University (MU) and the Joint Clinical Research Center (JCRC). MITHU's focus is on biomedical training in basic microbiology and immunology to be applied to HIV and HIV/AIDS-related diseases research. The program has been designed to meet the most essential training needs identified by colleagues in Uganda with a long-term goal of strengthening the biomedical research capacity of major universities and medical schools in Uganda. MITHU's Specific Aims are: 1. To strengthen Ugandan biomedical research capacity at the faculty level by supporting PhD level training in microbiology and immunology at CWRU of talented young Ugandan scientists who have completed Master's level training at MU. 2. To strengthen graduate education in biomedical sciences in Uganda by supporting Master's level training in the School of Biomedical Sciences at MU's College of Health Sciences. 3. To establish regional expertise on HIV and its complications by building on the infrastructure and ongoing research of the Uganda-CWRU Research Collaboration (UCRC). 4. To develop a culture of mentoring young and developing laboratory scientists through the Uganda Society of Health Scientists (USHS). 5. To continue close collaborations between MITHU and laboratories at JCRC and MU to provide advanced facilities for immunology and microbiology research in Uganda for training and for returning trainees. MITHU proposes a comprehensive, basic science program emphasizing training that addresses the changing circumstances imposed by the HIV epidemic in Uganda. The proposed program will balance education and training experiences between MU and CWRU, with Master's level training in Uganda and PhD training in the US. We will offer a course in Uganda on HIV and HIV/AIDS-related infections focused on the latest innovations in basic science and technology. This course will serve as a Core Course for the Master's program and will be team-taught by lecturers in Uganda and CWRU with expertise in the basic and clinical virology, pathogenesis and drug resistance of HIV, complications of HIV/AIDS, particularly HIV/TB, and basic and clinical immunology. As the cadre of young biomedical scientists grows in Uganda, there will be a demand for Ugandan mentors. MITHU will organize mentor training with USHS, a society organized by former Ugandan CWRU trainees. Research training in MITHU will build on the infrastructure and research activities of UCRC projects funded by NIH, CDC, B&MGF, EDTCP, and others. They create a robust environment for Master's training at MU and generate biomedical hypotheses for PhD training at CWRU.