Microbiology and Immunology Training for HIV and HIV-Related Research in Uganda (MITHU)

乌干达艾滋病毒和艾滋病毒相关研究微生物学和免疫学培训 (MITHU)

• 批准号: 10592269
• 负责人: W. Henry Boom
• 金额: $ 29.68万
• 依托单位: CASE WESTERN RESERVE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2016
• 资助国家: 美国
• 起止时间: 2016-05-01 至 2026-03-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10592269
• 关键词: Address; Biomedical Research; COVID-19 pandemic; Collaborations; Diagnosis; Distance Learning; Doctor of Philosophy; Educational workshop; Epidemic; Faculty; Funding; HIV; HIV/TB; Health Sciences; Immunology; Infection; Infrastructure; Institution; Internet; Journals; Mentors; Methods; Microbiology; Molecular; Prevention; Research; Research Personnel; Research Training; Rotation; Schools; Science; Scientist; Students; Training; Training Programs; Uganda; Universities; Work; college; doctoral student; faculty mentor; improved; lectures; meetings; next generation; pathogen; programs; research faculty; success

Abstract (450 words; 29 lines) This competing renewal builds on the success of the first 4 yrs. of the "Microbiology and Immunology Training for HIV and HIV-Related Research in Uganda” (MITHU) training program. MITHU addresses capacity building in basic/translational biomedical research on HIV and HIV-related complications in Uganda. Persistence of the HIV epidemic, compounded by the evolving SARS-CoV-2 (COVID-19) pandemic and other emerging infections, emphasizes the importance of lab-based research capacity in immunology and molecular microbiology for tracking, prevention, diagnosis and treatment. This capacity requires biomedical faculty at Makerere University (MU) and other institutions in Uganda to train the next generation of biomedical technicians, researchers and faculty. For this competing renewal, MITHU proposes the 5 New Aims. Aim 1. To continue MITHU's success in supporting biomedical MSc training at MU. We propose to continue MSc training as a primary Aim for this next funding cycle. The best MSc students will go on to biomedical PhD training. Aim 2. To expand Biomedical PhD Training at MU by starting a Sandwich PhD program in biomedical sciences with CWRU. We propose a Sandwich PhD where outstanding MSc students will be co-mentored by faculty from MU and CWRU, spend their first yr at CWRU for selected course work in immunology or molecular microbiology, to do lab rotations, and to select CWRU and MU mentors for their thesis project. Thesis research will begin at CWRU and will be completed at MU. This Sandwich PhD program is possible because there are now 9 biomedical research faculty in MU's School of Biomedical Sciences. Six of 9 were trained at CWRU, 2 trained at MU by the Uganda-CWRU Research Collaboration and 1 at Univ. of Wash. Aim 3. To continue mentoring of junior biomedical science faculty and providing re-entry support for returning PhD trainees as they establish themselves as biomedical faculty and researchers in Uganda. MITHU will continue to coordinate a mentoring program for junior and senior research scientists with the College of Health Sciences' NURTURE program. MITHU will also continue to provide re-entry support for PhD trainees returning to Uganda. Improved internet access has greatly improved distance-learning and intercontinental interactions, allowing for remote mentoring, lab meetings and journal clubs. Aim 4. To continue to sponsor the yearly short intensive course “Host- Pathogen interactions in HIV, TB and their complications. This popular course is attended by MU biomedical MSc, MMed and PhD students. This course is a mixture of lectures, journal clubs and workshops in which MU- and CWRU-sponsored scientists present the latest biomedical results and methods related to HIV and its complications. Aim 5. To continue to leverage for MITHU the Uganda-CWRU Research Collaboration's expertise and infrastructure for HIV and TB research for training in the biomedical sciences of HIV and its complications.

摘要(450字，29行) 这一竞争性续订建立在前4年的成功基础上。关于《微生物学与免疫学》的培训 乌干达艾滋病毒和艾滋病毒相关研究“(Mithu)培训方案。Mithu解决能力建设问题 在乌干达关于艾滋病毒和艾滋病毒相关并发症的基础/转化性生物医学研究。坚持不懈的 艾滋病毒流行，加上不断演变的SARS-CoV-2(新冠肺炎)大流行和其他新出现的 感染，强调以实验室为基础的免疫学和分子研究能力的重要性 用于跟踪、预防、诊断和治疗的微生物学。这一能力要求生物医学教师在 Makerere大学(MU)和乌干达其他机构培训下一代生物医学 技术人员、研究人员和教职员工。对于这种相互竞争的更新，米图提出了5个新目标。目标1.目标 延续Mithu在支持密歇根大学生物医学硕士培训方面的成功。我们建议继续进行硕士培训 作为下一个筹资周期的主要目标。最好的硕士学生将继续接受生物医学博士培训。目标 2.扩大墨尔本大学的生物医学博士培训，启动一个生物医学的三明治博士项目， CWRU。我们提出了一个三明治博士学位，在那里优秀的硕士学生将由密歇根大学的教师共同指导 和CWRU，在CWRU的第一年学习免疫学或分子微生物学的选定课程，以 做实验轮换，并为他们的论文项目选择CWRU和MU导师。论文研究将于 CWRU，并将在MU完成。这个三明治博士项目是可能的，因为现在有9个 慕尼黑大学生物医学科学学院的生物医学研究人员。9人中有6人在CWRU接受过培训，2人接受过培训 在MU被乌干达-CWRU研究合作和在大学1个。沃什。目标3.继续指导 初级生物医学教员，并为回国的博士生提供重新入学的支持 作为乌干达的生物医学教员和研究人员。Mithu将继续协调指导 与健康科学学院的培育计划一起为初级和高级研究科学家提供的计划。 米图还将继续为返回乌干达的博士生提供重新进入乌干达的支持。改进的互联网 Access极大地改进了远程学习和洲际互动，允许远程指导， 实验室会议和杂志俱乐部。目标4.继续赞助每年一度的短期强化课程“主持人- 艾滋病毒、结核病及其并发症中的病原体相互作用。这门受欢迎的课程由慕尼黑大学生物医学参加 硕士、医学硕士和博士生。这门课程混合了讲座、期刊俱乐部和研讨会，在这些课程中，MU- CWRU赞助的科学家展示了与艾滋病毒及其相关的最新生物医学结果和方法 并发症。目标5.继续利用乌干达-CWRU研究合作的Mithu 艾滋病毒和结核病研究的专门知识和基础设施，用于艾滋病毒和结核病的生物医学科学培训 并发症。