Physiology as a Potential Predictor of Perception in Cochlear Implants
Physiology as a Potential Predictor of Perception in Cochlear Implants
批准号:
9810168
负责人:
Michelle L Hughes
金额:
$29.16万
依托单位国家:
美国
项目类别:
财政年份:
2018
资助国家:
美国
项目状态:
已结题
起止时间:
2018-11-01 至 2020-07-31
中文摘要
项目总结/文摘
英文摘要
PROJECT SUMMARY/ABSTRACT
Our research program is aimed at improving the use of physiological measures to predict perception with
a cochlear implant (CI). The long-term goal is to objectively determine optimal speech-processor settings on an
individual basis to improve speech understanding. Although some studies have shown modest correlations
between objective and behavioral measures, these relations are not sufficiently strong to support exclusive use
of physiological measures to predict behavioral outcomes. Recent studies have shown that the standard pulse
polarity (cathodic-leading) used for CI stimulation is not ideal (e.g., Carlyon et al. 2013; Undurraga et al., 2010,
2013). Rather, more effective stimulation has been demonstrated using the opposite (anodic-leading) polarity
for both physiological and perceptual measures. These findings raise significant questions about how to
interpret the existing body of research aimed at relating physiological and perceptual measures, which used
standard cathodic-leading pulses. Although the recent studies demonstrated greater effectiveness with anodic
stimulation for both perceptual (i.e., louder percepts for a fixed current level) and physiological (i.e., shorter
latencies, larger amplitudes, more effective masking) responses, no studies to date have examined polarity
effects using standard clinical pulses, nor have any studies examined the relation between physiology and
perception as a function of stimulus polarity. This is the goal of the present project. If polarity affects
physiological measures to a different degree than perceptual measures, then the predictability of objective
measures will be affected. In this project, we will examine the effect of stimulus polarity using clinically
standard pulse shapes to determine the extent to which polarity affects perceptual and physiological measures,
as well as the relation between the two. Examining the effects of stimulus polarity for standard pulse shapes
will allow us to better understand the underlying physiological contributors to perceptual measures with CIs,
and will have important implications for future clinical stimulation paradigms. Most importantly, results from this
study will determine whether current clinical stimulation modes should shift from cathodic- to anodic-leading
stimulation.
期刊论文(3)
专著(0)
科研奖励(0)
会议论文
DOI:
10.1080/14670100.2016.1225348
发表时间:
2016-09
期刊:
Cochlear implants international
影响因子:
--
作者:
[Thomas Roland J, Buchman C, Eisenberg L, Henderson L, He S, Firszt J, Francis H, Dunn C, Sladen D, Arndt S, May B, Zeitler D, Niparko JK, Emmett S, Tucci D, Chen J, McConkey Robbins A, Schwefler E, Geers A, Lederberg A, Hayes H, Hughes M, Bierer J, Schafer E, Sorkin D, Kozma-Spytek L, Childress T]
通讯作者:
Childress T
Characterizing Polarity Sensitivity in Cochlear Implant Recipients: Demographic Effects and Potential Implications for Estimating Neural Health.
表征人工耳蜗植入者的极性敏感性:人口统计影响和估计神经健康的潜在影响。
DOI:
10.1007/s10162-021-00824-0
发表时间:
2022
期刊:
Journal of the Association for Research in Otolaryngology : JARO
影响因子:
--
作者:
[Hughes,MichelleL]
通讯作者:
Hughes,MichelleL
DOI:
10.1097/mao.0b013e31827c9d71
发表时间:
2013-02
期刊:
Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology
影响因子:
--
作者:
[Goehring JL, Hughes ML, Baudhuin JL, Lusk RP]
通讯作者:
Lusk RP
TELEPRACTICE FOR COCHLEAR IMPLANTS
-
批准号:8995651
-
项目类别:
-
资助金额:$31.62万
-
财政年份:2014
-
负责人:Michelle L Hughes
-
依托单位:
TELEPRACTICE FOR COCHLEAR IMPLANTS
-
批准号:8693331
-
项目类别:
-
资助金额:$30.87万
-
财政年份:2014
-
负责人:Michelle L Hughes
-
依托单位:
TELEPRACTICE FOR COCHLEAR IMPLANTS
-
批准号:9204823
-
项目类别:
-
资助金额:$31.62万
-
财政年份:2014
-
负责人:Michelle L Hughes
-
依托单位:
PHYSIOLOGY AS A POTENTIAL PREDICTOR OF PERCEPTION IN COCHLEAR IMPLANTS
-
批准号:8012826
-
项目类别:
-
资助金额:$27.98万
-
财政年份:2009
-
负责人:Michelle L Hughes
-
依托单位:
PHYSIOLOGY AS A POTENTIAL PREDICTOR OF PERCEPTION IN COCHLEAR IMPLANTS
-
批准号:7766900
-
项目类别:
-
资助金额:$28.91万
-
财政年份:2009
-
负责人:Michelle L Hughes
-
依托单位:
PHYSIOLOGY AS A POTENTIAL PREDICTOR OF PERCEPTION IN COCHLEAR IMPLANTS
-
批准号:9119808
-
项目类别:
-
资助金额:$38.25万
-
财政年份:2009
-
负责人:Michelle L Hughes
-
依托单位:
PHYSIOLOGY AS A POTENTIAL PREDICTOR OF PERCEPTION IN COCHLEAR IMPLANTS
-
批准号:8960282
-
项目类别:
-
资助金额:$41.25万
-
财政年份:2009
-
负责人:Michelle L Hughes
-
依托单位:
PHYSIOLOGY AS A POTENTIAL PREDICTOR OF PERCEPTION IN COCHLEAR IMPLANTS
-
批准号:7651686
-
项目类别:
-
资助金额:$29.2万
-
财政年份:2009
-
负责人:Michelle L Hughes
-
依托单位:
PHYSIOLOGY AS A POTENTIAL PREDICTOR OF PERCEPTION IN COCHLEAR IMPLANTS
-
批准号:8413774
-
项目类别:
-
资助金额:$26.58万
-
财政年份:2009
-
负责人:Michelle L Hughes
-
依托单位:
PHYSIOLOGY AS A POTENTIAL PREDICTOR OF PERCEPTION IN COCHLEAR IMPLANTS
-
批准号:8213442
-
项目类别:
-
资助金额:$27.98万
-
财政年份:2009
-
负责人:Michelle L Hughes
-
依托单位:
PHYSIOLOGY AS A POTENTIAL PREDICTOR OF PERCEPTION IN COCHLEAR IMPLANTS
-
批准号:7850084
-
项目类别:
-
资助金额:$14.6万
-
财政年份:2009
-
负责人:Michelle L Hughes
-
依托单位:
Short-Term Research Training for AuD Students
-
批准号:9037510
-
项目类别:
-
资助金额:$3.72万
-
财政年份:2007
-
负责人:Michelle L Hughes
-
依托单位:
CHANNEL INTERACTION IN COCHLEAR IMPLANTS
-
批准号:6927538
-
项目类别:
-
资助金额:$7.2万
-
财政年份:2005
-
负责人:Michelle L Hughes
-
依托单位:
CHANNEL INTERACTION IN COCHLEAR IMPLANTS
-
批准号:7022192
-
项目类别:
-
资助金额:$7.03万
-
财政年份:2005
-
负责人:Michelle L Hughes
-
依托单位:
CHANNEL INTERACTION IN COCHLEAR IMPLANTS
-
批准号:7213294
-
项目类别:
-
资助金额:$6.83万
-
财政年份:2005
-
负责人:Michelle L Hughes
-
依托单位:
国内基金
海外基金
Transient Receptor Potential 通道 A1在膀胱过度活动症发病机制中的作用
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批准号:30801141
-
项目类别:青年科学基金项目
-
资助金额:28.0万元
-
批准年份:2008
-
负责人:都书琪
-
依托单位: