Wearable Breath Sensors with Chip Integrated Mid-Infrared Slow Light Enhanced Absorbance Spectroscopy on Conformal Flexible Substrates

共形柔性基板上具有芯片集成中红外慢光增强吸收光谱的可穿戴呼吸传感器

• 批准号: 9394236
• 负责人: Swapnajit Chakravarty
• 金额: $ 15万
• 依托单位: OMEGA OPTICS, INC.
• 依托单位国家: 美国
• 财政年份: 2017
• 资助国家: 美国
• 起止时间: 2017-09-15 至 2018-02-28
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9394236
• 关键词: Adhesives; Air; Alcohols; Blood alcohol level measurement; Budgets; Carbon Dioxide; Cellular Phone; Chemical Warfare; Clothing; Communicable Diseases; Contracts; Coupling; Crystallization; Detection; Devices; Elements; Equipment; Ethanol; Feedback; Fire - disasters; Gases; Industrialization; Ink; Lasers; Law Enforcement; Length; Light; Malignant Neoplasms; Measurement; Measures; Military Personnel; Monitor; Nature; Optics; Pattern; Phase; Printing; Procedures; Research; Risk; Sapphire; Schedule; Semiconductors; Signal Transduction; Silicon; Silicon Dioxide; Silver; Specificity; Spectrum Analysis; Structure; System; Techniques; Technology; Testing; Texas; Thick; Time; TimeLine; Transducers; Translating; Universities; Wireless Technology; Work; absorption; alcohol monitoring; austin; base; design; detector; drug abuser; fighting; flexibility; indexing; light intensity; optical sensor; photonics; quantum; sensor; success; technical report; telecom-wavelength; vapor

Omega Optics and the University of Texas, Austin, propose wearable breath alcohol monitoring with a wearable chip-integrated infrared (IR) optical sensor on flexible substrate. Smart sensing is achieved by integrating the devices on flexible substrates with personal clothing. Integrated with Bluetooth on the flexible printed circuit board, the system will enable real time, continuous, remote monitoring, as also personalized warning notifiers for at-risk drivers and drug abusers. The chip-integrated absorption sensing of gases comprises a quantum cascade laser (QCL) and quantum cascade detector (QCD) wafer bonded to silicon passive waveguides in silicon-on- sapphire (SoS) wafer. Enhanced optical absorbance by the guided light is achieved by using an experimentally demonstrated mid-IR holey slotted photonic crystal waveguide (HPCW) in SoS, previously used for detection of chemical warfare simulant triethylphosphate. The principle of enhanced absorption relies on the phenomenon of slow light unique to PCW structures and enhanced optical field intensities in low index narrow slots that combine to increase the effective path length traversed by the guided wave through the sensed gas. In contrast to conventional QCLs and QCDs that rely on bulky electronic drive circuits and benchtop biasing equipment, this proposal transfers experimentally demonstrated printed circuit board based drive elements to a flexible Kapton substrate via demonstrated ink-jet printing techniques. Distributed feedbacks (DFB) QCLs on chip emitting multiple discrete wavelengths centered on =3.4µm and =4.2µm will monitor both ethanol and carbon dioxide (CO2) in breath respectively. Each QCD, corresponding to a QCL, measures light intensity after transduction by the intermediate HPCW. The integrated signal from QCDs generates the absorption spectrum. Change in absorption spectrum identifies the gas qualitatively and quantitatively, notifying wirelessly via Bluetooth to cell phones or remote devices. Our wearable platform can easily detect ethanol with absorption cross-section 2×10-19cm2/molecule, with specificity via absorbance signatures down to 20 parts per billion detection limits, lower than the 100ppb in breath corresponding to 0.02% blood alcohol concentration (BAC) level. The proposed sensing platform together with its potential integration with smart clothing and smart jewelry and accessories, will enable applications beyond breath alcohol monitoring to the monitoring of cancers and infectious diseases, in civilian and industrial air quality monitoring on airborne platforms, and in military, law-enforcement and fire-fighting applications. Our system is readily scalable to other wavelengths that will enable monitoring of other gases and vapors.

欧米茄光学和德克萨斯大学奥斯汀分校，提案可穿戴酒精监测 具有可穿戴的芯片集成红外（IR）光学传感器的柔性基材。智能传感器 可以通过将设备与私人服装集成在柔性基材上。融合的 使用弹性打印电路板上的蓝牙，系统将实时实时，连续， 远程监控，以及针对高危驾驶员和吸毒者的个性化警告通知器。 气体的芯片集成抽象感应包括量子级联激光（QCL） 和量子级联检测器（QCD）摇动粘合到硅的硅被动波导 - 蓝宝石（SOS）下注。通过使用一个通过使用的光吸收来增强光学吸收 实验证明了SOS中的Mid-Ir孔插入光子晶体波导（HPCW）， 以前用于检测化学战模拟三乙基磷酸盐。原则 增强的虐待依赖于PCW结构独有的慢光现象和 低指数狭窄的插槽中增强的光场强度，结合有效 路径长度由引导波穿过感应的气体。与传统相反 依靠笨重的电子驱动电路和台式偏置设备的QCL和QCD， 该提案通过实验证明了基于印刷电路板的驱动元件的转移 通过演示的喷墨打印技术来柔韧的Kapton底物。分布式 芯片排放上的反馈（DFB）QCLs以= 3.4µm为中心的多个离散波长 = 4.2µm将分别监测呼吸中的乙醇和二氧化碳（CO2）。每个 QCD，对应于QCL，测量中间体翻译后的光强度 HPCW。来自QCD的集成信号会产生抽象谱。更改 吸收光谱在定性和定量上识别气体，通过无线通知 蓝牙到手机或远程设备。我们的可穿戴平台可以轻松检测乙醇 吸收横截面2×10-19cm2/分子，具有吸光度特征 降至十亿次检测限制的20份，低于100ppb的呼吸 0.02％的血液酒精浓度（BAC）水平。 提出的感应平台以及其潜在的与智能服装的整合 智能珠宝和配饰，将使呼吸酒精监测以外的应用 在平民和工业空气质量监测中监测癌症和传染病 空降平台以及军事，执法和消防应用。我们的系统是 容易扩展到其他波长，这些波长可以监测其他气体和蒸气。