TB/MDR-TB Research Capacity Building in LMIC in Southeast Asia

 描述（申请人提供）：该培训项目的目标是加强结核病研究能力，特别是LMIC合作中心的结核病研究人力资源，即缅甸国家结核病计划;上缅甸和下缅甸医学研究部;泰国结核病局（BTB）;以及印度尼西亚北苏门答腊大学、西苏门答腊安达拉斯大学和亚齐西亚瓜拉大学。培训计划将侧重于耐多药结核病（MDR-TB），这是东南亚地区的一个主要问题。这将最终导致未来更好地控制结核病和其他全球传染病。该计划的目标是培训合作中心（LMIC-印度尼西亚，缅甸和泰国）的研究人员在宋卡王子大学获得流行病学硕士/博士学位，特别关注耐多药结核病研究，并为合作中心的各种研究人员提供结核病流行病学/生物统计学和结核病实验室科学的短期培训。培养6名博士和6名硕士毕业生的长期培训将在宋卡王子大学（EPI-PSU）流行病学单位进行，该单位在亚洲和非洲培养了130多名流行病学博士和硕士研究人员。这与在马希窦大学（MICRO-MU）微生物学系和在Yala区结核病中心12（ZTC 12）的结核病研究和结核病现场观察卓越中心的补充短期培训相结合。此外，还将在EPI-PSU进行短期培训，培训19名研究人员，并在MICRO-MU培训14名研究人员。所有受训人员将由缅甸、印度尼西亚和泰国的目标机构初步挑选，并由培训咨询小组审查。长期培训课程包括为期一年的课程（由博士和硕士课程共享），强调流行病学/生物统计学，研究方法，负责任的研究行为和数据分析。然后在受训人员的国内研究所收集与耐多药结核病有关的研究论文的数据（博士1年，硕士6个月）。最后，另外一年的博士和6个月的硕士学员将在EPI-PSU进行数据分析和报告撰写。除技术质素外，我们亦已作出安排，以确保学员足够多元化、最大限度地保留人才，以及在培训完成后继续进行研究事业发展。

 DESCRIPTION (provided by applicant): This training program's goal is to strengthen TB research capacity, especially human resources of TB research at LMIC collaborating centers, namely the National Tuberculosis Program of Myanmar; Department of Medical Research Upper and Lower Myanmar; Bureau of Tuberculosis of Thailand (BTB); and University of North Sumatra (USU), Andalas University of West Sumatra (UNAND), and Syiah Kuala University of Aceh (SKU), Indonesia. The training program will focus on multidrug-resistant TB (MDR-TB), which is a major problem in the Southeast Asia region. This will eventually lead to better future control of TB and other global infectious diseases. The program objectives are to train researchers from collaborating centers (LMIC-Indonesia, Myanmar and Thailand) to achieve MSc/PhD in Epidemiology at Prince of Songkla University, with a special focus on MDR-TB research, and to provide short course training in TB Epidemiology/Biostatistics and TB laboratory science to various researchers of the collaborating centers. The long-term training to produce 6 PhD and 6 MSc graduates will be based at the Epidemiology Unit, Prince of Songkla University (EPI-PSU), experienced in producing over 130 epidemiological Doctoral and Master researchers to Asia and Africa. This is incorporated with supplementary short-term training at the Departments of Microbiology at Siriraj Hospital and Faculty of Science of Mahidol University (MICRO-MU), and at a center of excellence for TB research and TB field observation at Zonal TB Center 12 Yala (ZTC12). In addition, short-term training will be conducted at EPI-PSU to train 19 researchers and at MICRO-MU to train 14 researchers. All trainees will be initially selected by the target institutes from Myanmar, Indonesia and Thailand, and reviewed by a Training Advisory Group (TAG). The long-term training curriculum consists of one year coursework (shared by PhD and MSc programs) emphasizing Epidemiology/Biostatistics, Research Methodology, Responsible Conduct of Research, and data analysis. This is followed by data collection for research thesis related to MDR-TB (1 year for PhD and 6 months for MSc) at home institutes of the trainees. Finally, another year for the PhD and 6 months for the MSc trainees will be spent on data analysis and report writing at EPI-PSU. Apart from technical quality, arrangement has been made to ensure enough diversity of trainees, maximum retention and continuation of research career development after the training has been completed.