Comparative Effectiveness Research & Cochrane Eyes and Vision (CEV)

项目概要/摘要 系统评价是比较有效性研究 (CER)，它使用明确的方法来识别、 评估并综合临床问题的可用证据。科克伦 (Cochrane) 是唯一一家国际 该组织的目标是综合并保持所有医疗保健领域的最新证据。 Cochrane Eyes and Vision (CEV) 旨在准备和促进干预措施的系统评价 用于预防或治疗眼部疾病和/或视力障碍，并帮助人们适应视力障碍 或失明。 12 年来，CEV 美国卫星 (CEV@US) 一直监督系统化生产 审查并为美国眼睛和视力领域的 CER 做出贡献。 CEV@US 的组织结构包括一个积极参与的顾问委员会、一个领导团队 由 PI 和两名高级联合研究员以及五个相互依赖的工作组组成，负责实施 与利益相关者合作伙伴的五个具体目标。 CEV@US 处于独特的地位，可以提供急需的、 持续为有关视力保健的明智决策做出贡献，从而对保护视力产生真正的影响 和预防失明。 我们的目标是让 CEV@US 继续作为美国眼睛和视力领域的 CER 中心。瞄准 1，我们将通过教育健康专业人员，在视觉科学领域建立一支 CER 劳动力队伍。我们的 教育灵活且量身定制，通过专业组织、临床机构在线和面对面提供 计划和一次性研讨会。在目标 2 中，我们将与个人（例如临床医生、患者）和 组织（例如，专业和专业协会、学术医疗中心、期刊）利益相关者 确保支撑临床实践的知识是可靠的、可用的和可应用的。我们的合作伙伴 策略是多维的、独特的和广泛的，并提供了支持临床医生作者的方法中心 和研究人员。目标 3：我们将准备系统审查，解决以下方面的优先问题： 与临床医生和方法学家合作，发布评论，并定期更新为新的 研究出现。我们将直接与临床医生合作，并应用最先进的方法来生产这些 评论。在目标 4 中，我们将开展与系统评价相关的基础方法学研究，以及 影响证据合成领域。在目标 5 中，我们将广泛传播我们的研究成果。 我们的传播策略旨在利用传统和电子手段产生影响。所有目标 总的来说，我们的方法将利用利益相关者合作伙伴的集体专业知识和观点 并领导建立 CER 社区。

PROEJCT SUMMARY/ABSTRACT Systematic reviews are comparative effectiveness research (CER) studies that use explicit methods to identify, appraise, and synthesize available evidence for a clinical question. Cochrane is the only international organization that has the goal of synthesizing and keeping up-to-date the evidence for all of healthcare. Cochrane Eyes and Vision (CEV) aims to prepare and promote access to systematic reviews of interventions used to prevent or treat eye conditions and/or visual impairment, and to help people adjust to visual impairment or blindness. For 12 years, CEV United States Satellite (CEV@US) has overseen production of systematic reviews and contributed to CER in eyes and vision in the US. The CEV@US's organizational structure comprises an engaged Advisory Board, a leadership team consisting of the PI and two senior Co-Investigators, and five interdependent workgroups who implement the five Specific Aims with stakeholder partners. CEV@US is in a unique position to make a much-needed, continued contribution to well-informed decisions about vision care, leading to real impact to preserving sight and prevention of blindness. Our objective is for CEV@US to continue to serve as the center for CER in eyes and vision in the US. In Aim 1, we will build a CER workforce within the field of vision science by educating health professionals. Our education is flexible and tailored, and is offered online and in-person, via professional organizations, clinical programs, and one-time workshops. In Aim 2, we will partner with individual (eg, clinicians, patients) and organizational (eg, professional and specialty societies, academic medical centers, journals) stakeholders to ensure that the knowledge underpinning clinical practice is reliable, available, and applied. Our partnership strategy is multidimensional, unique and extensive, and offers a methodologic hub supporting clinician-authors and researchers. In Aim 3: we will prepare systematic reviews that address prioritized questions in collaboration with clinicians and methodologists, publish the reviews, and regularly update them as new research emerges. We will work directly with clinicians and apply state-of-art methods in producing these reviews. In Aim 4, we will conduct foundational methodologic research related to systematic reviews, and influence the field of evidence synthesis. In Aim 5, we will disseminate the results of our research extensively. Our dissemination strategy is designed to having an impact, using traditional and electronic means. All aims taken together, our approach will leverage the collective expertise and perspectives of our stakeholder partners and lead the effort to build a CER community.