Comparative Effectiveness Research & the Cochrane Eyes & Vision Group

描述(申请人提供)：导致视力障碍和失明的眼病是发病率的重要来源，降低了所有年龄段的人的生活质量，并给卫生保健资源带来了巨大的负担。眼睛护理专业人员诊断视力障碍并进行视力保护治疗，他们依靠比较有效性研究的结果来做出知情的医疗保健决策。尽管迫切需要更好的信息，但在美国，进行眼睛和视力系统评估的现有基础设施很少，只有一家，Cochrane Collaboration的Eyes and Vision Group。美国卫星(CEVG)是特定学科的、可持续的、提供教育和促进合作的，只要研究是高质量的，任何人都可以做出贡献。CEVG@US。它自1997年以来一直在进行审查。确保对重要的眼睛和视力系统审查主题进行优先排序、执行、传播并保持最新；它教育和建设一支进行高质量系统审查的队伍；并为美国研究人员提供一个论坛，让他们在开发比较有效性研究方法方面发挥重要作用。在CEVG以往经验和成就的基础上，这项建议的总体目标是作为比较有效性研究的协调中心，特别是Cochrane在美国的眼睛和视觉的系统评估。这一角色相当于临床试验或临床研究网络的协调中心。具体地说，目标是1)在比较有效性研究方面教育和建设一支可持续的视力科学队伍；2)确定需要证据的目标领域；3)准备并保持针对目标问题的最新系统审查；4)对确定证据差距的方法进行研究；5)建立基于研究的、可公开获得的视力试验登记册；6)在系统审查中进行方法学研究；7)传播我们的研究结果。这项拟议的研究由Cochrane合作的长期基础设施提供服务，并由一个训练有素的研究团队领导。 相关性：通过开展和支持比较有效性研究，培训眼科和视力从业者和研究人员，传播健康信息，拟议工作的成果将对预防或治疗眼病和/或视力障碍，以及提高所有年龄段的人的生活质量产生重大影响。

DESCRIPTION (provided by applicant): Eye diseases leading to visual impairment and blindness are an important source of morbidity, decrease the quality of life for people of all ages, and place a substantial burden on health care resources. Eye care professionals, who diagnose vision disorders and practice sight-saving treatments, rely on findings from comparative effectiveness research to make well-informed health care decisions. Despite the critical need for better information, there are few established infrastructures for performing eyes and vision systematic reviews in the US only one, the Cochrane Collaboration's Eyes and Vision Group. US Satellite (CEVG(gUS) is subject specific, sustainable, provides education and facilitates collaboration by allowing anyone to contribute, as long as the research is high quality. CEVG@US. which has been producing reviews since 1997. ensures important eyes and vision systematic review topics are prioritized, performed, disseminated, and kept up-to-date; it educates and builds a workforce that performs high quality systematic reviews; and provides a forum for US researchers to play an instrumental role in developing methods for comparative effectiveness research. Building on CEVG's previous experiences and achievements, the over-arching objective of this proposal is to serve as a coordinating center for comparative effectiveness research, and specifically Cochrane systematic reviews, in eyes and vision in the US. This role is comparable to that of a coordinating center for a clinical trial or clinical research network. Specifically, the aims are to 1) educate and build a sustainable vision science workforce in comparative effectiveness research; 2) identify targeted areas where evidence is needed; 3) prepare and keep up-to-date systematic reviews addressing targeted questions; 4) conduct research on methods to identify evidence gaps; 5) build a study-based, publicly available vision trials register; 6) conduct methodological research in systematic reviews; 7) disseminate the results of our research. The proposed research is served by the long standing infrastructure of the Cochrane Collaboration, and is led by a highly trained research team. RELEVANCE: By conducting and supporting comparative effectiveness research, training eyes and vision practitioners and researchers, disseminating health information, the outcome of the proposed work will have substantial impact on preventing or treating eye diseases and/or visual impairment, and improving the quality of life for people of all ages.