Comparative Effectiveness Research & the Cochrane Eyes & Vision Group

描述（由申请人提供）：导致视力损害和失明的眼部疾病是发病的重要来源，降低了所有年龄段人群的生活质量，并对医疗资源造成了巨大负担。眼科护理专业人员诊断视力障碍和实施挽救视力的治疗，依靠比较有效性研究的结果来做出明智的医疗保健决策。 尽管迫切需要更好的信息，但在美国几乎没有建立起进行眼睛和视力系统评价的基础设施，只有一个，即科克伦协作组织的眼睛和视力小组。美国卫星（CEVG（gUS））是针对特定主题的，可持续的，提供教育，并通过允许任何人做出贡献来促进合作，只要研究是高质量的。CEVG@US。自1997年以来一直在进行审查。确保重要的眼睛和视觉系统评价主题的优先级，执行，传播，并保持最新;它教育和建立一支执行高质量系统评价的工作队伍;并为美国研究人员提供一个论坛，在开发方法方面发挥重要作用比较有效性研究。 基于CEVG以前的经验和成就，本提案的总体目标是作为美国眼睛和视力比较有效性研究的协调中心，特别是科克伦系统评价。这一角色相当于临床试验或临床研究网络的协调中心。具体而言，目标是1）教育和建立一个可持续的视觉科学劳动力在比较有效性研究; 2）确定需要证据的目标领域; 3）准备和保持最新的系统评价解决目标问题; 4）进行研究的方法，以确定证据差距; 5）建立一个基于研究的，公开的视力试验登记册; 6）在系统评价中进行方法学研究; 7）传播我们的研究成果。拟议的研究由科克伦协作网的长期基础设施提供服务，并由训练有素的研究团队领导。 相关性：通过开展和支持比较有效性研究，培训眼科和视力从业人员和研究人员，传播健康信息，拟议工作的成果将对预防或治疗眼疾和/或视力障碍产生重大影响，并提高所有年龄段人群的生活质量。

DESCRIPTION (provided by applicant): Eye diseases leading to visual impairment and blindness are an important source of morbidity, decrease the quality of life for people of all ages, and place a substantial burden on health care resources. Eye care professionals, who diagnose vision disorders and practice sight-saving treatments, rely on findings from comparative effectiveness research to make well-informed health care decisions. Despite the critical need for better information, there are few established infrastructures for performing eyes and vision systematic reviews in the US only one, the Cochrane Collaboration's Eyes and Vision Group. US Satellite (CEVG(gUS) is subject specific, sustainable, provides education and facilitates collaboration by allowing anyone to contribute, as long as the research is high quality. CEVG@US. which has been producing reviews since 1997. ensures important eyes and vision systematic review topics are prioritized, performed, disseminated, and kept up-to-date; it educates and builds a workforce that performs high quality systematic reviews; and provides a forum for US researchers to play an instrumental role in developing methods for comparative effectiveness research. Building on CEVG's previous experiences and achievements, the over-arching objective of this proposal is to serve as a coordinating center for comparative effectiveness research, and specifically Cochrane systematic reviews, in eyes and vision in the US. This role is comparable to that of a coordinating center for a clinical trial or clinical research network. Specifically, the aims are to 1) educate and build a sustainable vision science workforce in comparative effectiveness research; 2) identify targeted areas where evidence is needed; 3) prepare and keep up-to-date systematic reviews addressing targeted questions; 4) conduct research on methods to identify evidence gaps; 5) build a study-based, publicly available vision trials register; 6) conduct methodological research in systematic reviews; 7) disseminate the results of our research. The proposed research is served by the long standing infrastructure of the Cochrane Collaboration, and is led by a highly trained research team. RELEVANCE: By conducting and supporting comparative effectiveness research, training eyes and vision practitioners and researchers, disseminating health information, the outcome of the proposed work will have substantial impact on preventing or treating eye diseases and/or visual impairment, and improving the quality of life for people of all ages.