Quantitative and Computational Biology Graduate Program

定量和计算生物学研究生课程

• 批准号: 9266207
• 负责人: JOHN D STOREY
• 金额: $ 47.37万
• 依托单位: PRINCETON UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2004
• 资助国家: 美国
• 起止时间: 2004-08-18 至 2020-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9266207
• 关键词: Computational Biology; programs

 DESCRIPTION (provided by applicant): Support is requested for the renewal of an integrated, multidisciplinary training program for pre- doctoral trainees in genomics, with the goal of providing future scientists with the quantitative and computational tools necessary for successful biological research. The genome-training program supports students in Princeton University's Graduate Program in Quantitative and Computational Biology (QCB), a joint undertaking between the Lewis-Sigler Institute for Integrative Genomics and six main partner departments (Molecular Biology, Computer Science, Chemistry, Chemical and Biological Engineering, Physics, and Ecology and Evolutionary Biology) and administered by the Institute. Genomics trainees are able to do their lab rotations and thesis research with any of 35 QCB faculties in seven departments united by common interests in quantitative and computational biology, across a wide range of research areas. We request 12 pre-doctoral positions (our current level) each year during the proposed grant period. Trainees do experimental and computational research in: functional genomics in bacteria, eukaryotic models and mammalian systems; computational projects ranging from bioinformatics and molecular evolution to large-scale data analysis and visualization; systems biology projects ranging from microbial metabolism to the biophysics of embryonic development; and theoretical projects ranging from basic dynamical modeling to modeling signal transduction in epithelia or neurons. Trainees have individualized, efficient training plans, which span on average 5.3 years, for those who received their Ph.D. in the last ten years. Formal training includes courses in genomics and genomic analysis, a seminar series, a new journal club / presentation course, responsible conduct in research training appropriate for both experimental and computational research, and other multidisciplinary activities centered in the Institute. Trainees have the opportunity to teach in a new, innovative multidisciplinary introductory program for undergraduates at Princeton. Finally, trainees and eligible faculty participate in a number of activities designed to recruit and teach individuals who are members of under-represented minority groups.

 描述（由申请人提供）：要求支持更新基因组学博士前学员的综合多学科培训计划，目标是为未来的科学家提供成功生物学研究所需的定量和计算工具。基因组培训计划支持普林斯顿大学定量和计算生物学研究生课程（QCB）的学生，这是Lewis-Sigler综合基因组学研究所与六个主要合作部门（分子生物学，计算机科学，化学，化学和生物工程，物理学，生态学和进化生物学）之间的联合项目，并由该研究所管理。基因组学的学员能够做他们的实验室轮换和论文研究与任何35个QCB学院在七个部门由共同利益团结在定量和计算生物学，在广泛的研究领域。我们要求12个博士前职位（我们目前的水平），每年在拟议的补助金期间。受训人员在以下方面进行实验和计算研究：细菌，真核模型和哺乳动物系统的功能基因组学;从生物信息学和分子进化到大规模数据分析和可视化的计算项目;从微生物代谢到胚胎发育生物物理学的系统生物学项目;以及从基本动力学建模到上皮细胞或神经元信号转导建模的理论项目。学员有个性化的，有效的培训计划，平均跨度为5.3年，对于那些谁获得博士学位。在过去的十年里。正式培训包括基因组学和基因组分析课程，系列研讨会，新的期刊俱乐部/演示课程，适合实验和计算研究的负责任的研究培训行为，以及研究所集中的其他多学科活动。学员有机会在一个 普林斯顿大学为本科生开设的一个新的、创新的多学科入门课程。最后，受训人员和符合条件的教员参加一些活动，这些活动的目的是招聘和教授代表性不足的少数群体成员。