University of Wisconsin Regional Coordinating Center (UW RCC)

威斯康星大学区域协调中心 (UW RCC)

• 批准号: 9118381
• 负责人: ROBERT J DEMPSEY
• 金额: $ 37.63万
• 依托单位: UNIVERSITY OF WISCONSIN-MADISON
• 依托单位国家: 美国
• 财政年份: 2013
• 资助国家: 美国
• 起止时间: 2013-09-25 至 2018-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9118381
• 关键词: Automobile Driving; Awareness; Biometry; Blood Vessels; Caring; Catchment Area; Clinical; Clinical Trials; Collaborations; Communities; Community Health; Complex; Correlation Studies; Country; Data; Data Correlations; Degree program; Disease; Education; Elderly; Emergency Medicine; Enrollment; Equipment; Faculty; Family; Fostering; Funding; Goals; Health; Health Expenditures; Health system; Healthcare; Hospital Planning; Hospital Referrals; Hospitals; Housing; Human Resources; Information Networks; Institutes; Institutional Review Boards; Intensive Care; Intervention; Investigator-Initiated Research; Measures; Mentors; National Institute of Neurological Disorders and Stroke; Native Americans; Neurology; Outpatients; Patients; Pediatric Neurology; Performance; Phase; Physicians; Population; Prevention; Productivity; Protocols documentation; Provider; Public Health; Recovery; Recruitment Activity; Research; Research Infrastructure; Research Methodology; Research Personnel; Research Training; Resources; Rural; Satellite Hospitals; Services; Stroke; Stroke prevention; System; Time; Training; Translational Research; Translations; United States National Institutes of Health; Universities; Visit; Wisconsin; Work; acute stroke; base; certificate program; data management; effectiveness research; emergency service responder; experience; health disparity; health equity; implementation research; improved; innovation; meetings; member; neuroimaging; neurosurgery; outreach; patient population; preclinical trial; programs; public health relevance; stroke intervention; stroke rehabilitation; stroke symptom; success; trial design

DESCRIPTION (provided by applicant): The University of Wisconsin-Madison Regional Coordinating Stroke Center (UW RCC) wiii support the regional organization of national NIH Stroke Trials. This will include prevention, treatment, and recovery. This RCC infrastructure will be based on the already established Wisconsin Network for Health Research (WiNHR), an NIH-sponsored research consortium including academic, urban, rural, and underserved and health disparity populations. It includes four major health systems with a total of 12.7 million outpatient visits per year. In addition to the WiNHR network, 26 additional health entities have been recruited for participation in this RCC including Native American communities. Experience in data correlation, study coordination, and CTSA infrastructure, will assure innovative training and success in the effort. Our experience in collaborative research will foster translation of preclinical and clinical trials, as well as a proven ability to recruit stroke patients. This integration of neurosurgery, vascular neurology, neurosurgery, interventional neuroradiology, neuro-intensive care, stroke rehabilitation, emergency medicine, pediatric neurology, and innovative neuro- imaging will enhance productivity. Through investigator initiated stroke research, training and trial design, we propose to enhance the overall national programs in stroke research rather than simply manage trials. Our plan is: 1) to improve the pre-hospital plan for acute stroke through collaborations with satellite hospitals. 2) To utilize established networks such as the Wisconsin Network for Health Research (WiNHR), Collaborative Center for Health Equity (CCHE), Community Health Connections (CHC), and expanding Telestroke never for enjoyment of our diverse patient population in clinical trials. 3) To educate providers across the care spec aim at the pre-hospital, satellite hospital, and tertiary referral hospital setting. 4) To improve clinical, IRB,-and data management infrastructure for satellite hospitals through trial protocol and data management experts available within existing infrastructure at the University of Wisconsin including the Institute for Collaborative and Transitional Research (ICTR), Office of Clinical Trials (OCT), and the Mobile Research Team (MRT).

描述（由申请人提供）：威斯康星大学麦迪逊分校地区卒中协调中心 (UW RCC) 将支持国家 NIH 卒中试验的地区组织。这将包括预防、治疗和康复。该 RCC 基础设施将基于已经建立的威斯康星州健康研究网络 (WiNHR)，这是一个由 NIH 赞助的研究联盟，包括学术、城市、农村、服务不足和健康差距人群。它包括四大卫生系统，每年门诊量总计 1270 万人次。除了 WiNHR 网络之外，还招募了另外 26 个卫生实体参与该 RCC，其中包括美洲原住民社区。数据关联、研究协调和 CTSA 基础设施方面的经验将确保创新培训和工作的成功。我们在合作研究方面的经验将促进临床前和临床试验的转化，以及招募中风患者的经过验证的能力。神经外科、血管神经病学、神经外科、介入神经放射学、神经重症监护、中风康复、急诊医学、儿科神经病学和创新神经影像学的整合将提高生产力。通过研究者发起的中风研究、培训和试验设计，我们建议加强中风研究的整体国家计划，而不是简单地管理试验。我们的计划是：1）通过与卫星医院合作，完善急性脑卒中院前预案。 2) 利用已建立的网络，例如威斯康星州健康研究网络 (WiNHR)、健康公平合作中心 (CCHE)、社区健康连接 (CHC) 和不断扩大的远程中风，以便在临床试验中享受我们多样化的患者群体。 3) 对院前、卫星医院和三级转诊医院的医疗服务提供者进行护理规范教育。 4) 通过威斯康星大学现有基础设施（包括协作和过渡研究研究所 (ICTR)、临床试验办公室 (OCT) 和移动研究团队 (MRT)）内的试验方案和数据管理专家，改善卫星医院的临床、IRB 和数据管理基础设施。