CRCNS: Neurocomputational substrates of monetary exchange

该研究方案侧重于研究物品如何获得价值。特别是，我们的重点是 事实上，人类拥有无与伦比的能力来对物品进行价值评估，包括那些 没有“内在”价值。具体地说，我们试图阐明一组认知过程，这些过程使 有可能产生货币，并研究它们的神经基础。我们将使用 货币涌现的博弈论模型，并使用互补的方法进行实验 -功能神经成像(FMRI)和局灶性病变患者研究。我们的假设是，神经回路 在我们的货币涌现环境中参与战略学习建立在这些基础学习的基础上 关于奖励，但涉及与信念形成和心灵化相关的额外计算。 奖赏处理和决策过程中的障碍是药物滥用和成瘾的一个标志。AS 这样，对支持决策能力的神经机制有更深的理解 承诺在与NIDA使命相关的问题上提供新的线索。 相关性(请参阅说明)： 奖赏处理和决策过程中的障碍是药物滥用和成瘾的一个标志。通过 研究人们是如何对物品进行价值评估的，我们的目的是提供对行为的更深层次的理解 以及在药物滥用和成瘾过程中受到影响的神经过程。

The research proposal focuses on studying how objects come to acquire value. In particular, we focus on the fact that humans have an unparalleled capacity come to value objects, including those like money which have no "intrinsic" value. Specifically, we seek elucidate the set of cognitive processes that have made money-emergence possible, as well as investigate their neural underpinnings. We will do so using a game-theoretic model of money emergence and carry out experiments using complementary methodologies -functional neuroimaging (fMRI) and focal lesion patients studies. Our hypothesis is that the neural circuitry involved in strategic learning in our money emergence environments builds upon those underlying learning about rewards, but engages additional computations related to belief-formation and mentalization. Disturbances in reward processing and decision-making are a hallmark of drug abuse and addiction. As such, a deeper understanding of the neural mechanisms supporting decision-making capacity has the promise to shed new light on questions of relevance to the mission of NIDA. RELEVANCE (See instructions): Disturbances in reward processing and decision-making are a hallmark of drug abuse and addiction. By studying how people come to value objects, we aim to provide a deeper understanding of the behavioral and neural processes that are affected in drug abuse and addiction.