CRCNS: Neurocomputational substrates of monetary exchange

CRCNS：货币交换的神经计算基础

• 批准号: 9243339
• 负责人: Ming Hsu
• 金额: $ 11.6万
• 依托单位: UNIVERSITY OF CALIFORNIA BERKELEY
• 依托单位国家: 美国
• 财政年份: 2016
• 资助国家: 美国
• 起止时间: 2016-09-01 至 2019-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9243339
• 关键词: Address; Affect; Area; Behavior; Behavioral; Belief; Biological Sciences; Brain; Complex; Computer Simulation; Decision Making; Drug Addiction; Drug abuse; Economics; Environment; Foundations; Functional Magnetic Resonance Imaging; Game Theory; Goals; Human; Institution; Instruction; Journals; Knowledge; Learning; Learning Module; Lesion; Light; Marketing; Methodology; Methods; Mind; Mission; Modeling; Morphologic artifacts; National Institute of Drug Abuse; Nature; Neurobiology; Neurocognitive; Patients; Process; Psychological reinforcement; Publications; Research; Research Proposals; Rewards; Social Sciences; Structure; System; Techniques; Testing; Theoretical model; Uncertainty; Work; base; built environment; cognitive process; cohort; decision-making capacity; focal brain damage; interdisciplinary approach; interest; neural circuit; neural correlate; neuroeconomics; neuroimaging; neuromechanism; novel; relating to nervous system; research study; reward processing; social; social situation; symposium; theories

The research proposal focuses on studying how objects come to acquire value. In particular, we focus on the fact that humans have an unparalleled capacity come to value objects, including those like money which have no "intrinsic" value. Specifically, we seek elucidate the set of cognitive processes that have made money-emergence possible, as well as investigate their neural underpinnings. We will do so using a game-theoretic model of money emergence and carry out experiments using complementary methodologies -functional neuroimaging (fMRI) and focal lesion patients studies. Our hypothesis is that the neural circuitry involved in strategic learning in our money emergence environments builds upon those underlying learning about rewards, but engages additional computations related to belief-formation and mentalization. Disturbances in reward processing and decision-making are a hallmark of drug abuse and addiction. As such, a deeper understanding of the neural mechanisms supporting decision-making capacity has the promise to shed new light on questions of relevance to the mission of NIDA. RELEVANCE (See instructions): Disturbances in reward processing and decision-making are a hallmark of drug abuse and addiction. By studying how people come to value objects, we aim to provide a deeper understanding of the behavioral and neural processes that are affected in drug abuse and addiction.

该研究计划的重点是研究对象如何获得价值。我们特别关注 事实上，人类有一个无与伦比的能力来评估对象，包括那些像钱， 没有“内在”价值。具体来说，我们寻求阐明的认知过程，使 钱出现的可能性，以及调查他们的神经基础。我们将使用 货币出现的博弈论模型，并使用补充方法进行实验 - 功能性神经成像（fMRI）和局灶性病变患者研究。我们的假设是神经回路 在我们的货币涌现环境中，参与战略学习的人， 关于奖励，但涉及与信念形成和心智化相关的额外计算。 奖赏处理和决策的紊乱是药物滥用和成瘾的标志。作为 因此，更深入地了解支持决策能力的神经机制， 这将有助于对与NIDA的使命相关的问题进行新的阐述。 相关性（参见说明）： 奖赏处理和决策的紊乱是药物滥用和成瘾的标志。通过 通过研究人们如何评价物品，我们的目标是更深入地了解人们的行为， 和神经过程的影响，在药物滥用和成瘾。