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Mindfulness Meditation for the treatment of women with PTSD and SUD

正念冥想治疗患有 PTSD 和 SUD 的女性

基本信息

批准号：
9324991
负责人：
THERESE K KILLEEN
金额：
$ 36.18万
依托单位：
MEDICAL UNIVERSITY OF SOUTH CAROLINA
依托单位国家：
美国
项目类别：
财政年份：
2015
资助国家：
美国
起止时间：
2015-09-15 至 2020-07-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/9324991
关键词：
Address Adoption Affective Aftercare Alcohol consumption Alcohol or Other Drugs use Alcohols Area Awareness Back Behavior Therapy Behavioral Mechanisms Client satisfaction Cognitive Communities Comorbidity Confidence Intervals Data Detection Diagnosis Disease Drug abuse Drug usage Early Intervention Enrollment Equipment and supply inventories Evaluation Focus Groups Frequencies Grant Group Therapy Hybrids Individual Intervention Kentucky Legal Maintenance Manuals Measures Modification Monitor NIH Program Announcements Obsessive compulsive behavior Outcome Outcome Measure Outpatients Patient Self-Report Patients Pharmacology Pilot Projects Population Post-Traumatic Stress Disorders Preclinical Drug Evaluation Preventive Intervention Procedures Process Provider Randomized Randomized Controlled Trials Risk Sample Size Sampling Sampling Studies Schedule Severities Social Functioning Substance Use Disorder Suggestion Suicide attempt Supervision Symptoms TimeLine Training Trauma Treatment outcome Urine Violence Woman Women&apos s Group base behavior change clinically relevant disorder later incidence prevention drinking effective therapy emotion dysregulation emotion regulation epidemiology study follow-up interest men mindfulness mindfulness meditation novel physical abuse post intervention primary outcome programs public health relevance randomized trial safety and feasibility safety testing satisfaction substance abuse treatment symptomatology therapy development treatment adherence treatment as usual treatment effect treatment program

项目摘要

DESCRIPTION (provided by applicant): This study is a stage 1b behavioral therapy development grant exploring the use of Mindfulness Based Relapse Prevention (MBRP), an efficacious eight session group therapy for the treatment of individuals with substance use disorders, in women with comorbid PTSD and SUD enrolled in community substance abuse treatment. The MBRP manual will be adapted to address PTSD, specifically emotional dysregulation and reactivity. PTSD symptoms contributes to the onset and maintenance of substance use so addressing both disorders in an integrated fashion is indicated for successful outcomes. Women with comorbid PTSD and SUD represent a large proportion of patients treated in community substance abuse treatment. The revised manual will be piloted in a randomized control study with 80 women enrolled in women's intensive outpatient treatment. PTSD symptoms severity, substance use outcomes and measures of mindfulness and emotional regulation will be assessed at baseline, weekly throughout the intervention, post intervention and at 3-, and 6- month follow- ups. Women will be randomized to either MBRP plus treatment as usual (TAU) or TAU alone in a 2 (MBRP) to 1 (control) randomization schedule. The MBRP group will replace a trauma focused group routinely conducted in TAU. Outcomes process evaluation during the course of the project will guide the refinement of the manual to address issues related to PTSD. This proposed study addresses several of the program announcement specific areas of interest: 1) drug abuse treatment interventions, including interventions for patients with comorbidities, in diverse settings, 2) understanding the essential components and mechanism of behavior change using MBRP intervention, 3) treatment training and supervision to include procedures for adapting the intervention and fidelity measures for feasibility to be disseminated to community providers. Patient satisfaction and provider acceptability, feasibility and ease of implementation will be monitored to increase the potential for program adoption. If data gathered in this project is promising with an effect size estimation obtained, a larger randomized controlled study will be developed.