CENTERS OF EXCELLENCE FOR INFLUENZA RESEARCH AND SURVEILLANCE (CEIRS)

流感研究和监测卓越中心 (CEIRS)

• 批准号: 9463736
• 负责人: Adolfo Garcia-Sastre
• 金额: $ 719.55万
• 依托单位: ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI
• 依托单位国家: 美国
• 财政年份: 2014
• 资助国家: 美国
• 起止时间: 2014-04-01 至 2021-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9463736
• 关键词: Animals; Avian Influenza; Basic Science; Environmental Risk Factor; Evolution; Immune; Immune response; Influenza; Molecular; Pathogenicity; Research; improved; influenzavirus; pandemic disease; transmission process

To determine the molecular, ecologic and/or environmental factors that influence the evolution, emergence, transmission and pathogenicity of influenza viruses, including studies on animal influenza viruses with pandemic potential and to characterize the immune response to influenza infection to improve understanding of the immune correlates of protection and cross-protection.

确定影响流感病毒进化、出现、传播和致病性的分子、生态和/或环境因素，包括对具有大流行潜力的动物流感病毒的研究，并描述对流感感染的免疫反应，以提高对保护和交叉保护的免疫相关性的理解。