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Clinical and Translational Science Institute

临床与转化科学研究所

基本信息

批准号：
9317561
负责人：
Jennifer Rubin Grandis
金额：
$ 1702.44万
依托单位：
UNIVERSITY OF CALIFORNIA, SAN FRANCISCO
依托单位国家：
美国
项目类别：
财政年份：
2016
资助国家：
美国
起止时间：
2016-07-18 至 2021-05-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/9317561
关键词：
Achievement Area Biological Markers Biometry California Caring Child Clinical Clinical Data Clinical Research Clinical Sciences Clinical Trials Clinical Trials Unit Collaborations Communities Consent Consultations Data Data Sources Development Devices Diagnostic Diverse Workforce Elderly Electronic Health Record Emerging Technologies Enrollment Ensure Ethics Faculty Foundations Funding Goals Good Clinical Practice Health Human Resources Improve Access Incentives Individual Informatics Institutes Institutional Review Boards Knowledge Link Longevity Measurable Measurement Medical Mentors Methodology Nursing Research Operations Research Participant Policies Population Population Heterogeneity Precision Medicine Initiative Procedures Process Recruitment Activity Research Research Design Research Infrastructure Research Methodology Resources San Francisco Science Services System Technology Therapeutic Time Training Training Programs Training Support Translational Research Universities Vulnerable Populations Work Workforce Development base biobank cost cost effective digital epidemiology study evidence base flexibility health application health equity improved innovation mHealth meetings multidisciplinary named group population health precision medicine product development programs responsible research conduct safety net sensor social translational study

项目摘要

Contact PD/PI: Grandis, Jennifer Rubin Part 1 Overall Abstract The UCSF Clinical and Translational Science Institute (CTSI) has built a coordinated platform for clinical and translational research, successfully improved, integrated, and extended research services and infrastructure, and created comprehensive training programs. The program has expanded services and infrastructure by collaborating with regional partners, notably the 5 University of California CTSAs (UC BRAID), and measurably improved the health of vulnerable residents in the San Francisco Bay Area. Building on this foundational work, the CTSI now proposes to leverage these strengths by developing and linking emerging technologies to improve the quality, efficiency, and cost of conducting interdisciplinary, multisite clinical and translational research. This overarching goal will be achieved by coordinating informatics and technology with traditional research infrastructure, supported by highly effective training programs, and a traditionally strong focus on team science. These activities will also integrate expertise from and scale to CTSI's regional partners, UC BRAID, the CTSA national network, and PCORnet. The UCSF CTSI Overall Specific Aims will focus on: 1. Informatics and Research Innovation; 2. Community Engagement and Team Science; 3. Translational Workforce Development and Pilot Translational and Clinical Studies; 4. Expert Consultation and Regulatory Knowledge and Support; 5. Integrating Special Populations and Participant and Clinical Interactions; 6. Providing Liaison to NCATS' Trial and Recruitment Innovation Centers; 7. Product Development, and 8. Precision Medicine. Project Summary/Abstract Page 267 Contact PD/PI: Grandis, Jennifer Rubin

联系人 PD/PI：Grandis、Jennifer Rubin 第 1 部分总体摘要 UCSF 临床与转化科学研究所 (CTSI) 为临床和转化建立了一个协调平台转化研究，成功改进、整合和扩展研究服务和基础设施，并制定了全面的培训计划。该计划通过以下方式扩展了服务和基础设施与区域合作伙伴合作，特别是 5 个加州大学 CTSA (UC BRAID)，并可衡量改善了旧金山湾区弱势居民的健康。在此基础工作的基础上， CTSI 现在建议通过开发新兴技术并将其与以下领域联系起来来利用这些优势：提高进行跨学科、多地点临床和转化的质量、效率和成本研究。这一总体目标将通过协调信息学和技术与传统方法来实现研究基础设施，由高效的培训计划支持，以及传统上的强烈关注团队科学。这些活动还将整合 CTSI 区域合作伙伴 UC 的专业知识并扩大规模 BRAID、CTSA 国家网络和 PCORnet。 UCSF CTSI 总体具体目标将侧重于： 1. 信息学与研究创新； 2. 社区参与和团队科学； 3. 转化劳动力发展以及试点转化和临床研究； 4. 专家咨询和监管知识与支持； 5. 整合特殊人群以及参与者和临床互动； 6. 与 NCATS 的试验和招聘创新中心进行联络； 7. 产品开发，以及 8.精准医学。项目总结/摘要第 267 页联系人 PD/PI：Grandis、Jennifer Rubin