Family Outcomes in Autism Spectrum Disorders

自闭症谱系障碍的家庭结局

基本信息

  • 批准号:
    9223757
  • 负责人:
  • 金额:
    $ 39.93万
  • 依托单位:
  • 依托单位国家:
    美国
  • 项目类别:
  • 财政年份:
    2013
  • 资助国家:
    美国
  • 起止时间:
    2013-06-01 至 2020-02-29
  • 项目状态:
    已结题

项目摘要

DESCRIPTION (provided by applicant): It is now estimated that one in 88 children in the U.S. are diagnosed with an autism spectrum disorder (ASD). Few disabilities are more stressful on parents than ASD. There is theoretical and empirical evidence to suggest that chronic parenting stress affects marital adjustment. The overarching goal of this project is to examine the within-family associations between the autism symptoms and behavior problems of children with ASDs and marital adjustment as these processes unfold in naturalistic contexts and across three years. The specific study aims are: 1) Compare the self-reported and observed marital adjustment of couples of children with ASDs as compared to couples who have children without disabilities. 2) Test the within-family day-to-day temporal effects of child symptoms and behavior problems on couple interactions. 3) Examine the trajectories of global self-reported and observed marital adjustment across four waves of data collection spanning three years. In total, 175 married couples who have a child with an ASD aged five to 12 years will participate in the study. Study variables will be assessed through self-reported and teacher-reported measures and direct observations across four waves of data collection spanning three years. A matched comparison group of 150 married couples of children without a disability will also participate at Time 1 to understand how the processes in families of children with ASDs differ from normative experiences. Associations between marital adjustment and child symptoms and behavior problems will be examined using both a micro-level scale (14-day daily diary at Time 1), to examine the unfolding of real time day-to-day associations in their natural and spontaneous context, and a macro-level scale (four waves of data collection spanning three years), to examine the longer-term time-order pathways between these variables. Our primary unit of analysis is the couple, with individuals (husbands and wives) nested within couples. Multivariate multilevel modeling will be used to handle the inter-dependence of spouses' data collected at multiple time points (Raudenbush & Bryk, 2002).
描述(由申请人提供):据估计,美国每88名儿童中就有1名被诊断患有自闭症谱系障碍(ASD)。很少有残疾比自闭症谱系障碍对父母的压力更大。有理论和实证证据表明,长期的父母压力影响婚姻调整。这个项目的首要目标是研究自闭症儿童的自闭症症状和行为问题与婚姻调整之间的家庭内部联系,因为这些过程在自然环境下和三年的时间里展开。具体的研究目的是:1)比较有asd儿童的夫妇与无asd儿童的夫妇自我报告和观察到的婚姻适应情况。2)测试家庭内部儿童症状和行为问题对夫妻互动的日常时间效应。3)在跨越3年的四波数据收集中,检验全球自我报告和观察到的婚姻调整轨迹。共有175对已婚夫妇将参与这项研究,他们的孩子患有自闭症,年龄在5到12岁之间。研究变量将通过自我报告和教师报告的方法进行评估,并在跨越三年的四波数据收集中进行直接观察。另一个匹配的对照组是150对没有残疾孩子的已婚夫妇,他们也将参加第一次活动,以了解自闭症儿童家庭的过程与正常经历有何不同。将使用微观水平量表(时间1的14天每日日记)和宏观水平量表(跨越三年的四波数据收集)来检查婚姻调整与儿童症状和行为问题之间的关联,以检查在其自然和自发背景下实时日常关联的展开,以检查这些变量之间的长期时间顺序路径。我们的主要分析单元是夫妇,个体(丈夫和妻子)嵌套在夫妇中。多元多层模型将用于处理在多个时间点收集的配偶数据的相互依赖性(Raudenbush & Bryk, 2002)。

项目成果

期刊论文数量(2)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
Mothers' and Fathers' Prescription Drug Misuse in Family Contexts: Implications for the Adjustment of Parents of Children With and Without Autism.
母亲和父亲在家庭背景下滥用处方药:对患有和不患有自闭症儿童的父母的调整的影响。
  • DOI:
    10.1080/16066359.2017.1351552
  • 发表时间:
    2018
  • 期刊:
  • 影响因子:
    2.9
  • 作者:
    Papp,LaurenM;Hartley,SiganL
  • 通讯作者:
    Hartley,SiganL
Child-present and child-themed marital conflict in daily life of parents of children with and without autism spectrum disorder.
有或没有自闭症谱系障碍儿童的父母日常生活中存在儿童和以儿童为主题的婚姻冲突。
  • DOI:
    10.1037/dev0000631
  • 发表时间:
    2019
  • 期刊:
  • 影响因子:
    4
  • 作者:
    Papp,LaurenM;Hartley,SiganL
  • 通讯作者:
    Hartley,SiganL
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Sigan L Hartley其他文献

Prediction of amyloid and tau brain deposition and cognitive decline in people with Down syndrome using plasma biomarkers: a longitudinal cohort study
利用血浆生物标志物预测唐氏综合征患者的淀粉样蛋白和tau 蛋白脑沉积及认知能力下降:一项纵向队列研究
  • DOI:
    10.1016/s1474-4422(25)00158-9
  • 发表时间:
    2025-07-01
  • 期刊:
  • 影响因子:
    45.500
  • 作者:
    Shorena Janelidze;Lyduine E Collij;Niklas Mattsson-Carlgren;Alex Antill;Charles M Laymon;Ira Lott;H Diana Rosas;Davneet S Minhas;Weiquan Luo;Shahid Zaman;Alzheimer's Biomarker Consortium–Down Syndrome investigators;Mark Mapstone;Elizabeth Head;Florence Lai;Sigan L Hartley;Beau M Ances;Sharon J Krinsky-McHale;Joseph H Lee;Rik Ossenkoppele;Bradley T Christian;Benjamin L Handen;Oskar Hansson
  • 通讯作者:
    Oskar Hansson
Timeline to symptomatic Alzheimer's disease in people with Down syndrome as assessed by amyloid-PET and tau-PET: a longitudinal cohort study
唐氏综合征患者症状性阿尔茨海默病的时间线(通过淀粉样蛋白-PET 和 tau-PET 评估):一项纵向队列研究
  • DOI:
    10.1016/s1474-4422(24)00426-5
  • 发表时间:
    2024-12-01
  • 期刊:
  • 影响因子:
    45.500
  • 作者:
    Emily K Schworer;Matthew D Zammit;Jiebiao Wang;Benjamin L Handen;Tobey Betthauser;Charles M Laymon;Dana L Tudorascu;Annie D Cohen;Shahid H Zaman;Beau M Ances;Mark Mapstone;Elizabeth Head;Bradley T Christian;Sigan L Hartley;Howard Aizenstein;Beau Ances;Howard Andrews;Karen Bell;Rasmus Birn;Adam Brickman;Fan Zhang
  • 通讯作者:
    Fan Zhang

Sigan L Hartley的其他文献

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{{ truncateString('Sigan L Hartley', 18)}}的其他基金

Lifestyle and Alzheimer's Disease In Down Syndrome
生活方式与唐氏综合症中的阿尔茨海默病
  • 批准号:
    10098587
  • 财政年份:
    2020
  • 资助金额:
    $ 39.93万
  • 项目类别:
Lifestyle and Alzheimer's Disease In Down Syndrome
生活方式与唐氏综合症中的阿尔茨海默病
  • 批准号:
    10263355
  • 财政年份:
    2020
  • 资助金额:
    $ 39.93万
  • 项目类别:
Lifestyle and Alzheimer's Disease In Down Syndrome
生活方式与唐氏综合症中的阿尔茨海默病
  • 批准号:
    10474454
  • 财政年份:
    2020
  • 资助金额:
    $ 39.93万
  • 项目类别:
Lifestyle Risk and Resiliency Factors and Alzheimer’s Disease in Down syndrome
唐氏综合症中的生活方式风险和弹性因素以及阿尔茨海默病
  • 批准号:
    10669953
  • 财政年份:
    2020
  • 资助金额:
    $ 39.93万
  • 项目类别:
Lifestyle and Alzheimer's Disease In Down Syndrome
生活方式与唐氏综合症中的阿尔茨海默病
  • 批准号:
    10696137
  • 财政年份:
    2020
  • 资助金额:
    $ 39.93万
  • 项目类别:
Lifestyle and Alzheimer’s Disease In Down Syndrome- Life Stressors Supplement
生活方式和唐氏综合症中的阿尔茨海默病 - 生活压力补充剂
  • 批准号:
    10839520
  • 财政年份:
    2020
  • 资助金额:
    $ 39.93万
  • 项目类别:
Family Outcomes in Autism Spectrum Disorders
自闭症谱系障碍的家庭结局
  • 批准号:
    8524248
  • 财政年份:
    2013
  • 资助金额:
    $ 39.93万
  • 项目类别:
Family Outcomes in Autism Spectrum Disorders
自闭症谱系障碍的家庭结局
  • 批准号:
    8666667
  • 财政年份:
    2013
  • 资助金额:
    $ 39.93万
  • 项目类别:
Family Outcomes in Autism Spectrum Disorders
自闭症谱系障碍的家庭结局
  • 批准号:
    8806603
  • 财政年份:
    2013
  • 资助金额:
    $ 39.93万
  • 项目类别:
Post-Doctoral Training in Intellectual and Developmental Disabilities Research
智力和发育障碍研究博士后培训
  • 批准号:
    10395978
  • 财政年份:
    1995
  • 资助金额:
    $ 39.93万
  • 项目类别:

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